Aryl hydrocarbon receptor in club cells drives Th17-mediated lung injury following inhalation exposure to environmentally persistent free radicals. [PDF]
Pathak R +4 more
europepmc +1 more source
Using fish models to understand the role of aryl hydrocarbon receptor (AHR)-interacting protein (AIP) in controlling sensitivity and resistance to dioxin-like compounds in vivo. [PDF]
Karchner SI +14 more
europepmc +1 more source
E-cigarette exposure impairs skeletal muscle mitochondrial function in male mice. [PDF]
Mazirka P +9 more
europepmc +1 more source
Targeting the Aryl Hydrocarbon Receptor: The Potential of Indole Compounds in the Treatment of Cystic Fibrosis. [PDF]
Hou S, Yue Q, Hou X, Wu Q.
europepmc +1 more source
Activation of the aryl hydrocarbon receptor with structurally diverse ligands suppresses class switch to immunoglobulin A. [PDF]
Costa AB, DeKrey GK.
europepmc +1 more source
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Etoricoxib enhances aryl hydrocarbon receptor activity
Toxicology, 2023Etoricoxib is a nonsteroidal anti-inflammatory drug (NSAID) that possesses properties that include reducing inflammation and relieving pain and fever. Etoricoxib is an oral medication that selectively inhibits cyclooxygenase-2 with high efficacy. Controversies about its cardiovascular side effects have long existed.
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Aryl hydrocarbon receptor and colitis
Seminars in Immunopathology, 2013The aryl hydrocarbon receptor (AhR), a transcription factor activated by a large variety of natural and synthetic ligands, has recently become the object of great interest among researchers since it represents an important link between environment and immune-mediated pathologies.
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The Aryl Hydrocarbon Receptor Complex
Annual Review of Pharmacology and Toxicology, 1995The heteromeric unliganded aryl hydrocarbon receptor complex (AHRC) contains the aryl hydrocarbon receptor monomer (AHR). Binding of polycyclic or halogenated aromatic hydrocarbon (PAH and HAH) ligand causes release of AHR, which then associates with the AHR nuclear translocator protein (ARNT) to generate the heterodimeric "transformed" AHRC.
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