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The aryl hydrocarbon receptor: A comparative perspective
Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology, 1998The aryl hydrocarbon receptor (Ah receptor or AHR) is a ligand-activated transcription factor involved in the regulation of several genes, including those for xenobiotic-metabolizing enzymes such as cytochrome P450 1A and 1B forms. Ligands for the AHR include a variety of aromatic hydrocarbons, including the chlorinated dioxins and related halogenated ...
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Dexlansoprazole is an aryl hydrocarbon receptor agonist
Food and Chemical ToxicologyDexlansoprazole, a proton pump inhibitor, is commonly used to treat gastro-esophageal reflux disease and erosive esophagitis. The activated aryl hydrocarbon receptor (AhR) functions as a transcription factor by binding to the aryl hydrocarbon response element (AHRE) of its target genes, with cytochrome P450 (CYP) 1A1 being the most well-known target ...
Kuo-Liang Wei +6 more
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Aryl Hydrocarbon Receptor-Interacting Protein and Acromegaly
Hormone Research in Paediatrics, 2007<i>Background:</i> Recently, researchers at the Oulu University Hospital and the University of Helsinki identified a large pedigree segregating prolactinomas and somatotropinomas. Results suggest that this family from Northern Finland has a possible low penetrance of hereditary predisposition to development of pituitary adenoma, and in ...
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Clozapine and the aryl hydrocarbon receptor
Journal of Psychopharmacology, 2022openaire +2 more sources
Nuclear receptors, the aryl hydrocarbon receptor, and macrophage function
Molecular Aspects of Medicine, 2021Sara Lamorte +2 more
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Aryl hydrocarbon receptor ligands in cancer: friend and foe
Nature Reviews Cancer, 2014Gary H Perdew +2 more
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