Biochemical Characterization of Arylamine N-acetyltransferases From Vibrio vulnificus [PDF]
Xinning Liu +11 more
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Effect of Rifampin on Thyroid Function Test in Patients on Levothyroxine Medication [PDF]
BackgroundLevothyroxine (LT4) and rifampin (RIF) are sometimes used together; however, no clinical studies have assessed the effects of these drugs on thyroid function or the need to adjust LT4 dose.MethodsWe retrospectively reviewed the records of 71 ...
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Indonesia is the second highest country with TB patients in the world. Diabetes mellitus (DM) is a comorbid of TB. Arylamine N-acetyltransferase 2 (NAT2), encoded by the NAT2 gene, is an enzyme that metabolizes isoniazid (INH).
Alvinsyah Adhityo Pramono +5 more
doaj +1 more source
Breast Cancer and Active and Passive Smoking: The Role of the N-Acetyltransferase 2 Genotype [PDF]
The association of breast cancer with passive and active smoking was investigated in slow and fast acetylators of aromatic amines in a Geneva, Switzerland, study in 1996-1997.
Bernstein, M. S. +4 more
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Tackling tuberculosis: insights from an international TB Summit in London [PDF]
Tuberculosis (TB) poses a grave predicament to the world as it is not merely a scientific challenge but a socio-economic burden as well. A prime cause of mortality in human due to an infectious disease; the malady and its cause, Mycobacterium ...
Anuradha HK +14 more
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CYP2E1 genotype and isoniazid-induced hepatotoxicity in patients treated for latent tuberculosis [PDF]
Objective: To determine whether pharmacogenetic tests such as N-acetyltransferase 2 (NAT2) and cytochrome P4502E1 (CYP2E1) genotyping are useful in identifying patients prone to antituberculosis drug-induced hepatotoxicity in a cosmopolite population ...
Chiappe, Alberto +8 more
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The case for hypervirulence through gene deletion in Mycobacterium tuberculosis.
Deletion of genes in a pathogen is commonly associated with a reduction in its ability to cause disease. However, some rare cases have been described in the literature whereby deletion of a gene results in an increase in virulence.
Bancroft, Gregory J +4 more
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Quantification of global transcription patterns in prokaryotes using spotted microarrays [PDF]
We describe an analysis, applicable to any spotted microarray dataset produced using genomic DNA as a reference, that quantifies prokaryotic levels of mRNA on a genome-wide scale.
Bacon, J +12 more
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Phenotyping of N -acetyltransferase type 2 and xanthine oxidase with caffeine: when should urine samples be collected? [PDF]
Objectives: Individual activities of N-acetyltransferase 2 (NAT2) and of xanthine oxidase (XO) can be assessed using ratios of urinary caffeine metabolites.
Fuhr, Uwe +5 more
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Evidence that TRPM8 is an androgen-dependent Ca2+ channel required for the survival of prostate cancer cells [PDF]
615 CHESTNUT ST, 17TH FLOOR, PHILADELPHIA, USA, PA, 19106 ...
Barritt, Gregory John, Zhang, L
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