Deciphering the role of human arylamine N-acetyltransferase 1 (NAT1) in breast cancer cell metabolism using a systems biology approach. [PDF]
, 2018 Background: Human arylamine N-acetyltransferase 1 (NAT1) is a phase II xenobiotic metabolizing enzyme found in almost all tissues. NAT1 can additionally hydrolyze acetyl-coenzyme A (acetyl-CoA) in the absence of an arylamine substrate.
Carlisle, Samantha Marie
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Inhibitory Actions of Berberine on Growth and Arylamine N-Acetyltransferase Activity in Strains of Helicobacter Pylori from Peptic Ulcer Patients [PDF]
, 1999 Jing‐Gung Chung +6 more
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N-Acetyltranserase 2 (NAT2) genotype polymorphism in cryopreserved human hepatocytes and Chinese hamster ovary (CHO) cells. [PDF]
, 2020 Arylamine N-acetyltransferases, NAT1 and NAT2, catalyze the detoxification and/or activation of drugs and aromatic amine carcinogens. Single nucleotide polymorphisms or SNPs result in different human NAT2 genotypes thus dividing the population into rapid,
Habil, Mariam Refaat Zaky
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Genetic association studies of schizophrenia using the 8p21-22 genes: prepronociceptin (PNOC), neuronal nicotinic cholinergic receptor alpha polypeptide 2 (CHRNA2) and arylamine N-acetyltransferase 1 (NAT1) [PDF]
, 2001 Ekaterini Blaveri +12 more
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Metabolomics of transformed MDA-MB-231 cell lines expressing different levels of human arylamine N-acetyltransferase 1 (NAT1). [PDF]
, 2015 Human arylamine N-acetyltransferase 1 (NAT1) is a phase II xenobiotic metabolizing enzyme that is found in almost all tissues of the body. Expression of NAT1 is commonly elevated in several cancers including breast cancer. However, the exact mechanism by
Carlisle, Samantha Marie
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Functional analysis of N-acetyltransferase (NAT1*14B and NAT1*10) in complete NATb and NATa mRNA. [PDF]
, 2011 N-acetyltransferase 1 (NAT1) is a phase II metabolic enzyme responsible for the biotransformation of aromatic and heterocyclic amine carcinogens such as 4-aminobiphenyl (ASP).
Millner, Lori Michele
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NAT— from bugs to brains An overview of the 2nd International Workshop on the arylamine N-acetyltransferases [PDF]
, 2002 Fernando Rodrigues‐Lima +3 more
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Expression of the genes for arylamine N-acetyltransferases in mice [PDF]
, 2002 Arylamine N-acetyltransferases (NATs) are polymorphic enzymes involved in the metabolism of arylamine and hydrazine xenobiotics. Murine NAT isoenzymes are encoded by three Nat genes.
Boukouvala, Sotiria +1 more
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Acinar Distribution of Rat Liver Arylamine N‐Acetyltransferase: Effect of Chronic Ethanol and Endotoxin Exposure [PDF]
, 2002 P.S. Pronko +2 more
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NAT2 gene polymorphisms and plasma isoniazid concentration in Vietnamese tuberculosis patients
Walailak Journal of Science and Technology, 2019 Background: Isoniazid (INH) is one of the most common drug for tuberculosis (TB) treatment and INH acetylation catalysed by non-inducible hepatic enzyme arylamine N-acetyltransferase type 2 (NAT2).
Anh Tuan Le +4 more
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