Results 31 to 40 of about 22,861 (258)
Molecules, 2022 In the present study, pyrazole-thiophene-based amide derivatives were synthesized by different methodologies. Here, 5-Bromothiophene carboxylic acid (2) was reacted with substituted, unsubstituted, and protected pyrazole to synthesize the amide.
Iram Kanwal +8 more
doaj +1 more source
Gold-Catalyzed Alkenylation and Arylation of Phosphorothioates [PDF]
, 2023 Reported herein is the gold-catalyzed alkenylation and arylation of phosphorothioates using alkenyl and aryl iodides. The facile transmetalation between Ag-sulfur complex and Au(III) intermediate formed after oxidative addition is the key to the success ...
Urvashi, Urvashi +2 more
core +2 more sources
Catalytic C-F Bond Activation at Room Temperature: Enolate Cross-Couplings Enabled by [Pd(1-MeNAP)TFA]<sub>2</sub> and LiHMDS. [PDF]
Angew Chem Int Ed EnglCatalysts generated from the trifluoroacetate‐bridged methylnaphthyl‐palladium dimer [Pd(1‐MeNAP)TFA]2 and biarylphosphine ligands in combination with the base LiHMDS promote α‐arylation reactions of various enolates with non‐activated aryl fluorides at room temperature.
Krüger N +4 more
europepmc +2 more sources
Synthesis of Morphinans through Anodic Aryl‐Aryl Coupling
The Chemical Record, 2021 AbstractThe morphinans are an important class of structurally fascinating and physiologically important natural products as exemplified by the famous opium alkaloids of the morphine family. Although this class of secondary metabolites from the juice of the opium poppy capsule was already used for medicinal purposes thousands of years ago, chemical ...
Nina Vierengel +3 more
openaire +4 more sources
Insights into the Mechanism and Regioselectivity of Palladium-Catalyzed Arylation of α,β-Unsaturated Ketones [PDF]
, 2023 Transition-metal catalyzed coupling reactions of carbonyl compounds using simple chemical feedstocks have become a cornerstone of modern synthetic organic chemistry.
Xiaoxi, Su +3 more
core +2 more sources
Angewandte Chemie, EarlyView.A new type of Si─Me bond activation enabling catalytic alkyl exchange at Si was developed. It involves a P‐directing group and Pd─Lewis acid cooperation. It enables the conversion of Me3SiCl into silanols with three different organic substituents. ABSTRACT A novel mode of Si─Me bond activation has been unveiled through the cooperative action of a P ...
Hajime Kameo +5 more
wiley +2 more sources
Heck Transformations of Biological Compounds Catalyzed by Phosphine-Free Palladium
Molecules, 2018 The development and optimization of synthetic methods leading to functionalized biologically active compounds is described. Two alternative pathways based on Heck-type reactions, employing iodobenzene or phenylboronic acid, were elaborated for the ...
Stanisława Tarnowicz-Ligus +1 more
doaj +1 more source
Beilstein Journal of Organic Chemistry, 2020 An efficient synthesis of tetrabenzo[a,d,j,m]coronene derivatives having alkyl and alkoxy substituents at the 3, 6, 13, and 16-positions was achieved based on the ruthenium-catalyzed coupling reactions of anthraquinone derivatives with arylboronates via ...
Seiya Terai +3 more
doaj +1 more source
Angewandte Chemie, EarlyView.Pd‐catalyzed C–H arylation of polycyclic aromatic hydrocarbons (PAHs) with various aryltrimethylsilanes enables the preparation of structurally complicated arylated PAHs, which can be further transformed to nanographenes in a manner of two‐step annulative π‐extension (APEX) reaction.
Honami Katsuragawa +5 more
wiley +2 more sources
Sulfur Mediated Allylic C-H Arylation, Epoxidation and Aziridination [PDF]
, 2019 Transition-metal-free, sulfur mediated allylic C-H arylation, epoxidation and aziridination were realized through one-pot procedures. The reaction design involved initial addition between olefins and triflic anhydride activated sulfoxides, followed by ...
Gang, Hu, Hang, Luo, Pingfan, Li
core +1 more source