Arylesterase Phenotype-Specific Positive Association Between Arylesterase Activity and Cholinesterase Specific Activity in Human Serum [PDF]
International Journal of Environmental Research and Public Health, 2014 Context: Cholinesterase (ChE) specific activity is the ratio of ChE activity to ChE mass and, as a biomarker of exposure to cholinesterase inhibitors, has a potential advantage over simple ChE activity. Objective: To examine the association of several potential correlates (serum arylesterase/paraoxonase activity, serum albumin, sex, age, month of blood
Aoki, Yutaka +2 more
openaire +2 more sources
Depletion of B-cells with rituximab improves endothelial function and reduces inflammation among individuals with rheumatoid arthritis. [PDF]
, 2014 BackgroundIndividuals with rheumatoid arthritis (RA) are at increased risk for cardiovascular disease, partly due to systemic inflammation and endothelial dysfunction.
Del Puerto, Gus +10 more
core +2 more sources
Separation and quantitative recovery of mouse serum arylesterase and carboxylesterase activity
Journal of Lipid Research, 2004 Paraoxonase-1 (PON1) is known to be associated with high density lipoproteins. We optimized buffer conditions to obtain quantitative recovery of PON1 (arylesterase) activity and analyzed the distribution of PON1 in mice using a combination of size ...
Philip W. Connelly +2 more
doaj +1 more source
Frontiers in Medicine, 2020 Background: High-density lipoprotein (HDL) plays an essential role in the immune system and shows effective antioxidative properties. We investigated correlations of lipid parameters with the sequential organ failure assessment (SOFA) score and the ...
A. Reisinger +10 more
semanticscholar +1 more source
Clinics, 2010 INTRODUCTION: Laparoscopic cholecystectomy is the gold standard for the treatment of gallstone disease; however, adverse hemodynamic changes induced by increased intraabdominal pressure due to pneumoperitoneum are known to occur.
Hande Koksal, Sevil Kurban
doaj +1 more source
PON1 status does not influence cholinesterase activity in Egyptian agricultural workers exposed to chlorpyrifos. [PDF]
, 2012 Animal studies have shown that paraoxonase 1 (PON1) genotype can influence susceptibility to the organophosphorus pesticide chlorpyrifos (CPF). However, Monte Carlo analysis suggests that PON1 genotype may not affect CPF-related toxicity at low exposure ...
Bonner, Matthew R +6 more
core +1 more source
Türk Biyokimya Dergisi, 2023 We aimed to evaluate PON1 QR192 polymorphism’s (rs662) effects on levels of triglyceride, total cholesterol, high-density lipoprotein-cholesterol, low-density lipoprotein-cholesterol, glucose, and c-reactive protein, and paraoxonase-arylesterase ...
Akbalik Hasim +6 more
doaj +1 more source
Effects of cumin extract on oxLDL, paraoxanase 1 activity, FBS, total cholesterol, triglycerides, HDL-C, LDL-C, Apo A1, and Apo B in in the patients with hypercholesterolemia. [PDF]
, 2014 OBJECTIVES Paraoxanase 1 (PON1) plays a protective role against the oxidative modification of plasma lipoproteins and hydrolyzes lipid peroxides in human atherosclerotic lesions.
Farrokhi, E., Ghatreh Samani, K.
core +3 more sources
Relationship of Serum Paraoxonase Enzyme Activity and Thermal Burn Injury
Eurasian Journal of Medicine, 2019 Objective: This study investigated changes in serum oxidative stress parameters in burn cases compared to healthy controls. Materials and Methods: This study was performed in 41 burn patients with mild to severe thermal burn injuries and 38 healthy ...
Serap Yildirim +5 more
doaj +1 more source
Functional Trade-Offs in Promiscuous Enzymes Cannot Be Explained by Intrinsic Mutational Robustness of the Native Activity. [PDF]
, 2016 The extent to which an emerging new function trades off with the original function is a key characteristic of the dynamics of enzyme evolution. Various cases of laboratory evolution have unveiled a characteristic trend; a large increase in a new ...
Emond, S +3 more
core +4 more sources