Results 51 to 60 of about 7,599 (254)
Unlocking Lactonase Enzymes as Biocatalysts for the Deracemisation of Chiral γ‐Thiolactones
Angewandte Chemie, Volume 137, Issue 29, July 14, 2025.The application of lactonase enzymes as biocatalysts still remains underexplored. This study discloses the biocatalytic activity of two lactonases in the deracemisation of chiral C3‐substituted‐γ‐thiolactones. The biocatalyst GcL catalyses the enzymatic kinetic resolution (EKR) of C3‐amide‐thiolactones, while the rationally engineered biocatalyst N9 ...
Jingyue Wu +7 more
wiley +2 more sources
Functional Trade-Offs in Promiscuous Enzymes Cannot Be Explained by Intrinsic Mutational Robustness of the Native Activity. [PDF]
, 2016 The extent to which an emerging new function trades off with the original function is a key characteristic of the dynamics of enzyme evolution. Various cases of laboratory evolution have unveiled a characteristic trend; a large increase in a new ...
Emond, S +3 more
core +4 more sources
Protein glycosylation in lung cancer from a mass spectrometry perspective
Mass Spectrometry Reviews, Volume 45, Issue 3, Page 455-475, May/June 2026.ABSTRACT Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi +2 more
wiley +1 more source
The relationship between serum ferritin levels and serum lipids and HDL function with respect to age and gender [PDF]
The Ukrainian Biochemical Journal, 2016 Elevated serum ferritin (SFer) levels have been associated with chronic diseases such as coronary heart disease and diabetes mellitus type 2. The aim of this study was to examine the relationship between SFer levels and serum lipid parameters, and how ...
Hamit Yasar Ellidag +5 more
doaj +1 more source
Purification of Bovine Plasma Arylesterase
Journal of Dairy Science, 1967 Abstract Bovine plasma arylesterase was purified by: 1) precipitation between 50 and 75% saturation with (NH 4 ) 2 SO 4 at 0C, 2) chromatography of a solution of the precipitate on Sephadex G-200, 3) rechromatography of the pooled enzyme fractions on DEAE-cellulose at pH 7.8, and 4) removal of a precipitate formed when the pooled fractions from (3 ...
S.S. Choi, T.L. Forster
openaire +1 more source
Proteomic diversity of high-density lipoprotein explains its association with clinical outcome in patients with heart failure [PDF]
, 2017 Aims: Previously, low high-density lipoprotein (HDL) cholesterol was found to be one of the strongest predictors of mortality and/or heart failure (HF) hospitalisation in patients with HF.
Adams +26 more
core +5 more sources
Prostate International, 2017 Background Oxidative stress and antioxidants have been implicated in many diseases including prostate cancer and benign prostatic hyperplasia (BPH). Lipid peroxidation contributes to oxidative stress.
G. Asare +6 more
semanticscholar +1 more source
Advanced Science, Volume 13, Issue 22, 17 April 2026.In this study, a highly robust N‐glycoproteomics (HRN) platform with a newly developed match‐between‐run scheme is used for biomarker discovery. This study proposes a protein‐centric strategy to prioritize proteins susceptible to aberrant glycosylation.
Lei Liu +15 more
wiley +1 more source
Comparison of four different algorithms for the calculation of radioimmunoassay standard curves [PDF]
, 1980 Peer ...
Herndl, R. +2 more
core +2 more sources
Türk Kardiyoloji Derneği Arşivi, 2017 Objective: Oxidative stress is increased in patients with acute myocardial infarction (AMI). Statins reduce oxidative stress independent of their effect in reducing low-density lipoprotein cholesterol (LDL-C).
Celal Kilit +2 more
doaj +1 more source