Results 71 to 80 of about 3,977 (203)

EFFECT OF CARBON TETRACHLORIDE UPON ARYLESTERASES IN MICE

Japanese Journal of Pharmacology, 1970
Early works by Augustinsson (1-4) demonstrated that three types of esterases exist in vertebrate plasma in regard to substrate specificity and susceptibility to selective inhibitors, and he classified them into arylesterases [EC 3. 1. 1. 2], aliesterases (carboxylesterases) [EC 3.1.1.1] and cholinesterases [EC 3.1.1.8].
TAKAHASHI, NORIMIRTSU, NAKAZAWA, MASAO, WATANABE, TADASHI   +2 more
openaire   +3 more sources

The Proteomic Landscape of the Coronary Accessible Heart Cell Surfaceome

PROTEOMICS, Volume 25, Issue 7, April 2025.
ABSTRACT Cell surface proteins (surfaceome) represent key signalling and interaction molecules for therapeutic targeting, biomarker profiling and cellular phenotyping in physiological and pathological states. Here, we employed coronary artery perfusion with membrane‐impermeant biotin to label and capture the surface‐accessible proteome in the neo ...
Iasmin Inocencio, Alin Rai, Daniel Donner, David W. Greening   +3 more
wiley   +1 more source

Investigation of the Molecular Mechanisms of Paraoxonase‐2 Mediated Radiotherapy and Chemotherapy Resistance in Oral Squamous Cell Carcinoma

Clinical and Translational Science, Volume 18, Issue 4, April 2025.
ABSTRACT Oral squamous cell carcinoma (OSCC) is a common form of cancer, with 390,000 new cases estimated for 2022. OSCC has a poor prognosis, largely due to a high recurrence rate and resistance to therapy. Cancer cells develop resistance to standard therapy owing to various factors, such as genetic predispositions, alterations in the apoptotic ...
Mehta Vedant Kamal, Krishnananda Prabhu, Krishna Sharan, Ananth Pai, Sanjiban Chakrabarty, Rama Rao Damerla, Preethi S. Shetty, Vijetha Shenoy Belle, Mahadev Rao, Naveena A. N. Kumar   +9 more
wiley   +1 more source

Relationship of Serum Paraoxonase Enzyme Activity and Thermal Burn Injury

Eurasian Journal of Medicine, 2012
Objective: This study investigated changes in serum oxidative stress parameters in burn cases compared to healthy controls. Materials and Methods: This study was performed in 41 burn patients with mild to severe thermal burn injuries and 38 healthy ...
Serap Yildirim, Songul Doganay, Abdulkadir Yildirim, Osman Enver Aydin, Akar Karakoc, Esra Laloglu   +5 more
doaj  

Modulation of paraoxonase 1 and 3 expression after moderate exercise training in the rat

Journal of Lipid Research, 2009
Paraoxonases (PONs) are a small family of antioxidant enzymes whose antiatherogenic activity is well known. The aim of the present study was the evaluation of the effects of moderate aerobic training on their expression using a rat model.
Rita Romani, Gianna Evelina De Medio, Simona di Tullio, Rosa Lapalombella, Irene Pirisinu, Vittoria Margonato, Arsenio Veicsteinas, Marina Marini, Gabriella Rosi   +8 more
doaj   +1 more source

Connection between oral health and chronic diseases

MedComm, Volume 6, Issue 1, January 2025.
Mechanisms linking oral health to chronic diseases. The figure highlights oral health connections to diabetes, cardiovascular diseases, rheumatoid arthritis, and respiratory diseases. Key mechanisms include inflammation, microbial dysbiosis, oxidative stress, and immune dysregulation, emphasizing the systemic impacts of oral diseases like periodontitis.
Di Fu, Xingyue Shu, Ge Zhou, Mengzhen Ji, Ga Liao, Ling Zou   +5 more
wiley   +1 more source

Levels of paraoxonase and arylesterase activities and malondialdehyde in workers exposed to ionizing radiation

, 2003
We examined levels of malondialdehyde (MDA) (an end-product of lipid peroxidation) and paraoxonase (PON1) (an antioxidant enzyme) activity and PON1 phenotypes in people who were exposed to ionizing radiation for different time periods and doses.
Serhatlıoğlu, S, Gödekmerdan, A, Gülcü, F, Gürsu, MF, Canatan, Halit   +4 more
core   +1 more source

Serum Paraoxonase and Arylesterase Activities in Hemodialysis Patients

Journal of Atherosclerosis and Thrombosis, 2000
Cardiac death from atherosclerosis is common in hemodialysis patients. Human serum paraoxonase (PON1), an esterase, is associated with high-density lipoprotein and inhibits the susceptibility to oxidization of low-density lipoprotein (LDL). The PON1 genetic polymorphisms of 192 Gln/Arg and 55 Leu/Met in the amino acid sequence are partly involved in ...
Itahara, Takashi, Suehiro, Tadashi, Ikeda, Yukio, Inoue, Mari, Nakamura, Toshihiro, Kumon, Yoshitaka, Kawada, Masui, Hashimoto, Kozo   +7 more
openaire   +3 more sources

Determination of the possibility of usage of arylesterase types in the description of quail lines

, 1999
Çalışılan 4 farklı Japon bıldırcını hattında arilesteraz tipleri belirlenmiş ve EsA* fenotiplerinin frekansları yüksek bulunmuştur. Log-doğrusal model kullanılarak bıldırcın populasyonlarında fenotip ve genotip gruplarının belirlenmesinde arilesteraz ...
Çamdeviren, Handan, Yıldız, Ali Mehmet, Kesici, Tahsin   +2 more
core  

Human paraoxonases (PON1, PON2, and PON3) are lactonases with overlapping and distinct substrate specificities

Journal of Lipid Research, 2005
The paraoxonase (PON) gene family in humans has three members, PON1, PON2, and PON3. Their physiological role(s) and natural substrates are uncertain. We developed a baculovirus-mediated expression system, suitable for all three human PONs, and optimized
Dragomir I. Draganov, John F. Teiber, Audrey Speelman, Yoichi Osawa, Roger Sunahara, Bert N. La Du   +5 more
doaj   +1 more source