Results 61 to 70 of about 7,533 (241)
Paraoxonase Activity and Genotype Predispose to Successful Aging [PDF]
The paraoxonase 1 codon 192 R allele has been previously reported to have a role in successful aging. The relationship between PON1 genotypes, enzymatic activity, and mass concentration was evaluated in a group of 229 participants from 22 to 104 years of
Boemi, Massimo +9 more
core
Proteomic diversity of high-density lipoprotein explains its association with clinical outcome in patients with heart failure [PDF]
Aims: Previously, low high-density lipoprotein (HDL) cholesterol was found to be one of the strongest predictors of mortality and/or heart failure (HF) hospitalisation in patients with HF.
Adams +26 more
core +5 more sources
Protein glycosylation in lung cancer from a mass spectrometry perspective
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi +2 more
wiley +1 more source
Serum arylesterase and paraoxonase activities in patients with ovarian tumors
Objective: High levels of toxic reactive oxygen species have been found in many types of cancer cells. Serum arylesterase (ARE) and paraoxonase (PON) are esterase enzymes that have strong antioxidant characteristics.
Slawomir Michalak +4 more
doaj +1 more source
The Structure and Function of Paraoxonase-1 and Its Comparison to Paraoxonase-2 and -3
Serum paraoxonase-1 (PON1) is the most studied member of the group of paraoxonases (PONs). This enzyme possesses three enzymatic activities: lactonase, arylesterase, and paraoxonase activity.
Ajda Taler-Verčič +2 more
doaj +1 more source
Aim: The aims of this study are to evaluate the serum levels of paraoxonase (PON) and arylesterase (ARE) in breast cancer (BC) patients; to determine their relationship with chemotherapy requirements in BC; and to find a cut-off value to assess subjects ...
Y. Okuturlar +7 more
semanticscholar +1 more source
Serum paraoxonase-1 activity and risk of incident cardiovascular disease:The PREVEND study and meta-analysis of prospective population studies [PDF]
Background: Paraoxonase-1 (PON-1) has been suggested to be associated with cardiovascular disease (CVD) risk, however, aspects of the association, such as shape and independence from conventional risk factors are still uncertain.
Bakker, Stephan J L +3 more
core +2 more sources
Mass spectrometry in ocular drug research
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo +6 more
wiley +1 more source
Pur po se: The aim was to compare total oxidative stress (TOS), total antioxidant capacity (TAC), and paraoxonase (PON1), arylesterase (ARE), and lipid peroxidase (LPO) levels in the aqueous humor and concurrent venous blood serum and to evaluate the ...
Cengiz Caner +6 more
doaj +1 more source
Blood and semen paraoxonase—arylesterase activities in normozoospermic and azoospermic men
Paraoxonase and arylesterase enzymes are corner stones of antioxidant defence. We aimed to compare azoospermic infertile men and normozoospermic individuals with respect to total antioxidant status (TAS), total oxidant status (TOS), oxidative stress ...
M. Gulum +7 more
semanticscholar +1 more source

