Results 51 to 60 of about 25,056,579 (316)
Radioimmunoassay for arylsulfatase A in urine.
Clinical Chemistry, 1985 Abstract Purified arylsulfatase A (EC 3.1.6.1) from human urine was radioiodinated under conditions that caused no significant loss of antigenic activity. We used this labeled arylsulfatase A (specific radioactivity 4-7.5 Ci/g) together with nonlabeled enzyme and rabbit antiserum produced against homogeneous enzyme to develop a ...
R L Van Etten +4 more
openaire +3 more sources
Journal of Neuroscience, 2014 Enzyme replacement therapy (ERT) is a treatment option for lysosomal storage disorders (LSDs) caused by deficiencies of soluble lysosomal enzymes. ERT depends on receptor-mediated transport of intravenously injected recombinant enzyme to lysosomes of ...
Annika Böckenhoff +7 more
semanticscholar +1 more source
The BM@N spectrometer at the NICA accelerator complex [PDF]
arXiv, 2023 BM@N (Baryonic Matter at Nuclotron) is the first experiment operating and taking data at the Nuclotron/NICA ion-accelerating complex.The aim of the BM@N experiment is to study interactions of relativistic heavy-ion beams with fixed targets. We present a technical description of the BM@N spectrometer including all its subsystems.
arxiv
Pseudomonas aeruginosa arylsulfatase: a purified enzyme for the mild hydrolysis of steroid sulfates.
Drug Testing and Analysis, 2015 The hydrolysis of sulfate ester conjugates is frequently required prior to analysis for a range of analytical techniques including gas chromatography-mass spectrometry (GC-MS). Sulfate hydrolysis may be achieved with commercial crude arylsulfatase enzyme
B. Stevenson +6 more
semanticscholar +1 more source
Computational analysis of bacterial sulfatases and their modifying enzymes [PDF]
, 1998 The sequence analysis of enzymes that might modify bacterial sulfatases should be useful in the task of identifying the human sulfatase-modifying homologs — enzymes that are defective in the rare inherited disease multi-sulfatase ...
Kolter, Roberto, Schirmer, Andreas
core +1 more source
Central Precocious Puberty in a Child With Metachromatic Leukodystrophy
Frontiers in Endocrinology, 2018 Metachromatic leucodystrophy (MLD) is a rare inherited lysosomal disorder caused by reduced activity of the enzyme arylsulfatase A with accumulation of sulfatides in the nervous system.
Gilda Belli +6 more
doaj +1 more source
Nonclinical comparability studies of recombinant human arylsulfatase A addressing manufacturing process changes. [PDF]
PLoS ONE, 2018 Recombinant human arylsulfatase A (rhASA) is in clinical development for the treatment of patients with metachromatic leukodystrophy (MLD). Manufacturing process changes were introduced to improve robustness and efficiency, resulting in higher levels of ...
Teresa Wright +6 more
doaj +1 more source
Localization of arylsulfatase in Pseudomonas C12B [PDF]
Applied and Environmental Microbiology, 1977 Arylsulfatase was released almost completely from intact cells of Pseudomonas C12B after osmotic shock or after treatment with lysozyme. These results suggest that the enzyme is cell wall associated in this soil isolate.
J R George, J W Fitzgerald
openaire +3 more sources
Faithful flatness of Hopf algebras over coideal subalgebras with a conditional expectation [PDF]
arXiv, 2023 Let $H$ be a Hopf algebra and let $A\subset H$ be a right coideal subalgebra. We show that if $A$ is a direct summand in $H$ as a right $A$-module, then $H$ is faithfully flat as a right $A$-module.
arxiv
Genomic blueprints of sponge-prokaryote symbiosis are shared by low abundant and cultivatable Alphaproteobacteria [PDF]
, 2019 Marine sponges are early-branching, filter-feeding metazoans that usually host complex microbiomes comprised of several, currently uncultivatable symbiotic lineages.
Cox, Cymon +6 more
core +4 more sources