Results 61 to 70 of about 32,342 (273)

Role of Glutathione-Ascorbate Cycle and Photosynthetic Electronic Transfer in Alternative Oxidase-Manipulated Waterlogging Tolerance in Watermelon Seedlings

Horticulturae, 2021
Alternative oxidase (AOX) has been documented to mitigate the oxidative stress caused by abiotic stresses. However, it remains unknown how AOX regulates the antioxidant system and photosynthesis under waterlogging.
Jiawen Zheng, Chunying Fang, Lei Ru, Nan Sun, Yuanyuan Liu, Yunping Huang, Yuhong Wang, Zhujun Zhu, Yong He   +8 more
doaj   +1 more source

Novel insight into functions of ascorbate peroxidase in higher plants: More than a simple antioxidant enzyme

Redox Biology, 2023
As plants are sessile organisms, they are inevitably exposed to a variety of environmental stimuli that trigger rapid changes in the generation and disposal of reactive oxygen species such as hydrogen peroxide (H2O2).
Shengchun Li
doaj   +1 more source

Antioxidant Systems are Regulated by Nitric Oxide-Mediated Post-translational Modifications (NO-PTMs) [PDF]

, 2016
Nitric oxide (NO) is a biological messenger that orchestrates a plethora of plant functions, mainly through post-translational modifications (PTMs) such as S-nitrosylation or tyrosine nitration.
Juan C. Begara-Morales, Beatriz Sánchez-Calvo, Mounira Chaki, Raquel Valderrama, Capilla Mata-Pérez, María N. Padilla, Francisco J. Corpas, Juan B. Barroso   +7 more
core   +1 more source

Interaction of triacontanol and arsenic on the ascorbate-glutathione cycle and their effects on the ultrastructure in Coriandrum sativum L. [PDF]

, 2017
Exogenous application of triacontanol (TRIA) has the ability to mitigate the adverse effects of abiotic stresses by modulating a number of physio-biochemical processes in different plants.
BASILE, ADRIANA, Batool, Keramat, Elham Asadi, Karam, Hossein, Mozafarid, MARESCA, VIVIANA, SORBO, SERGIO, Zahra, Asrara   +6 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

The role of peroxiredoxins in cancer [PDF]

, 2017
Peroxiredoxins (PRDXs) are a ubiquitously expressed family of small (22-27 kDa) non-seleno peroxidases that catalyze the peroxide reduction of H2O2, organic hydroperoxides and peroxynitrite.
CAPALBO, CARLO, COPPA, Anna, D'INZEO, SONIA, GIANNINI, Giuseppe, NICOLUSSI, Arianna   +4 more
core   +1 more source

Inhibition of SLC11A1‐Mediated Lysosomal Iron Accumulation in Microglia Promotes Repair Following White Matter Stroke

Advanced Science, EarlyView.
Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu, Yajie Zhang, Yushi Tang, Hongli Hu, Ying Zhang, Junwen Xue, Hao Wang, Yecheng Wang, Chunfeng Liu, Jia Jia, Jian Cheng, Yongjun Cao   +11 more
wiley   +1 more source

Characterization of the antioxidant system during the vegetative development of pea plants

Biologia Plantarum, 2010
The antioxidative system was studied during the development of pea plants. The reduced glutathione (GSH) content was higher in shoots than in roots, but a greater redox state of glutathione existed in roots compared with shoots, at least after 7 d of ...
P. Díaz-Vivancos, G. Barba-Espín, M. J. Clemente-Moreno, J. A. Hernández   +3 more
doaj   +1 more source

Ascorbate-mediated regulation of growth, photoprotection, and photoinhibition in Arabidopsis thaliana. [PDF]

, 2018
The requirements for ascorbate for growth and photosynthesis were assessed under low (LL; 250 µmol m-2 s-1) or high (HL; 1600 µmol m-2 s-1) irradiance in wild-type Arabidopsis thaliana and two ascorbate synthesis mutants (vtc2-1 and vtc2-4) that have 30%
Alexander V Ruban, Alexandra J Townsend, Aller, Aro, Asada, Awad, Baier, Barbara Karpinska, Bartoli, Bartoli, Bashandy, Bratt, Brwa Rasool, Christine H Foyer, Cohu, Conklin, de Simone, de Simone, Demmig-Adams, Dowdle, Dutilleul, Foyer, Foyer, Foyer, Foyer, Foyer, Gallie, Giacomelli, Greenberg, Guo, Heber, Heyneke, Horling, Jahns, Jahns, Kangasjärvi, Karpinska, Karpinska, Kerchev, Kiddle, Kromdijk, Lichtenthaler, Lim, Mano, Maruta, Meyer, Miyaji, Munné-Bosch, Müller-Moulé, Müller-Moulé, Neff, Noctor, Nurhayati Razak, Osmond, Page, Pastori, Pavet, Pignocchi, Powles, Queval, Rouhier, Ruban, Ruban, Sarah Alomrani, Shaikhali, Smirnoff, Smirnoff, Tamaoki, Taylor, Tedone, Tyystjärvi, Tyystjärvi, Tóth, Vanderauwera, Wang, Ware, Wheeler, William Plumb, Yabuta, Yin, Zechmann, Zhang, Zhang   +82 more
core   +2 more sources

Suppressor of gamma response 1 modulates the DNA damage response and oxidative stress response in leaves of cadmium-exposed Arabidopsis thaliana [PDF]

, 2020
Cadmium (Cd) exposure causes an oxidative challenge and inhibits cell cycle progression, ultimately impacting plant growth. Stress-induced effects on the cell cycle are often a consequence of activation of the DNA damage response (DDR).
Cuypers, Ann, De Veylder, Lieven, Eekhout, Thomas, Hendrix, Sophie, Horemans, Nele, Huybrechts, Michiel, Iven, Verena, Keunen, Els, Pecqueur, Ingeborg, Vangronsveld, Jaco   +9 more
core   +1 more source