Retrospective Evaluation of Clinical Experience With Intravenous Ascorbic Acid in Patients With Cancer. [PDF]
BACKGROUND: Intravenous ascorbic acid (IV AA) has been used extensively in cancer patients throughout the United States. Currently, there are limited data on the safety and clinical effects of IV AA.
Bazzan, Anthony J. +4 more
core +2 more sources
Changes of protein fractions in wheat flour caused by additives
The influence of different combinations of reducing and oxidising agents (L-cysteine hydrochloride monohydrate + L-ascorbic acid, inactivated dry yeast + L-ascorbic acid, L-threonine + L-ascorbic acid, L-tryptophan + L-ascorbic acid) on the change in the
Pavlína Pečivová +2 more
doaj +1 more source
Ascorbic acid: A useful reductant to avoid oxidation of catecholamines in electrophysiological experiments in vitro? [PDF]
The actions of the reductant ascorbic acid on rat neocortical neurons in vitro was investigated by means of intracellular recordings. At a concentration (500 μM), which reduced the magnitude of dopamine degradation in oxygen-saturated saline solutions by
Sutor, Bernd, Ten Bruggencate, Gerrit
core +1 more source
Ascorbic acid and copper in linoleate oxidation. II. Ascorbic acid and copper as oxidation catalysts
Both ascorbic acid and copper were strong prooxidants in the oxidation of linoleate in a buffered (pH 7.0) aqueous dispersion at 37°C. Minimum concentrations at which catalytic activity was detected were 1.3 × 10-7m for copper and 1.8 × 10-6m for ...
Gottfried Haase, W.L. Dunkley
doaj +1 more source
Effects of Ascorbic Acid Deficiencies on Larvae of \u3ci\u3eLymantria Dispar\u3c/i\u3e (Lepidoptera: Lymantriidae) [PDF]
We assessed the effects of ascorbic acid and total vitamin deficiencies on growth, food processing efficiencies and survival of larval gypsy moths. Artificial diet lacking ascorbic acid did not alter performance of fourth instars, whereas diet lacking a ...
Lindroth, Richard L, Weiss, Anthony P
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Trolox and ascorbic acid reduce direct and indirect oxidative stress in the IPEC-J2 cells, an in vitro model for the porcine gastrointestinal tract [PDF]
Oxidative stress in the small intestinal epithelium is a major cause of barrier malfunction and failure to regenerate. This study presents a functional in vitro model using the porcine small intestinal epithelial cell line IPEC-J2 to examine the effects ...
De Smet, Stefaan +7 more
core +6 more sources
L-Ascorbic Acid: A Multifunctional Molecule Supporting Plant Growth and Development
L-Ascorbic acid (vitamin C) is as essential to plants as it is to animals. Ascorbic acid functions as a major redox buffer and as a cofactor for enzymes involved in regulating photosynthesis, hormone biosynthesis, and regenerating other antioxidants ...
Daniel R. Gallie
doaj +1 more source
Objective: To improve in vitro embryo production in buffalo by supplementation of L-ascorbic acid during maturation and development (experiment 1) and combination with another antioxidant as cysteamine (experiment 2).Methods: Two experiments were ...
Al-shimaa Al-H H l-Naby +4 more
doaj +1 more source
Diverse antitumor effects of ascorbic acid on cancer cells and the tumor microenvironment
Ascorbic acid has attracted substantial attention for its potential antitumor effects by acting as an antioxidant in vivo and as a cofactor in diverse enzymatic reactions.
Takeru Maekawa +3 more
doaj +1 more source
Phase I safety trial of intravenous ascorbic acid in patients with severe sepsis [PDF]
Background Parenterally administered ascorbic acid modulates sepsis-induced inflammation and coagulation in experimental animal models. The objective of this randomized, double-blind, placebo-controlled, phase I trial was to determine the safety of ...
Aamer A Syed +13 more
core +2 more sources

