Results 91 to 100 of about 5,480 (216)

Effectiveness and safety of BCD180, anti-TRBV9⁺ T-lymphocytes monoclonal antibody in patients with active radiographic axial spondyloarthritis: 36-week results of double-blind randomized placebo-controlled phase II clinical study ELEFTA

Научно-практическая ревматология
The aim – to evaluate the clinical effectiveness, safety, pharmacokinetics, pharmacodynamics, and immunogenicity of seniprutug (BCD-180) in patients with radiographic active axial spondyloarthritis (r-axSpA, or ankylosing spondylitis).Subjects and ...
E. L. Nasonov, V. I. Mazurov, A. M. Lila, T. V. Dubinina, I. Z. Gaydukova, S. A. Lapshina, A. A. Klimenko, D. V. Somov, S. A. Lukianov, D. M. Chudakov, I. V. Zvyagin, O. V. Britanova, M. A. Korolev, D. I. Abdulganieva, D. G. Krechikova, A. A. Kastanayan, L. V. Eliseeva, R. R. Samigullina, T. V. Povarova, O. V. Antipova, S. A. Smakotina, V. N. Soboleva, O. B. Nesmeyanova, T. V. Plaksina, N. F. Soroka, I. B. Vinogradova, A. P. Rebrov, T. V. Kropotina, A. L. Maslyanskiy, A. V. Zinkina-Orikhan, Yu. N. Lin’kova, P. S. Pukhtinskaia, M. A. Morozova, G. A. Vinderskaya   +33 more
doaj   +1 more source

Data Study Group Final Report: ASDA

, 2022
Data Study Groups are week-long events at The Alan Turing Institute bringing together some of the country’s top talent from data science, artificial intelligence, and wider fields, to analyse real-world data science challenges. Exploring and quantifying the effect of weather on sales ASDA, one of the biggest supermarket chains in the UK, is interested ...
openaire   +1 more source

Disease Activity and Patient-Reported Health Measures in Relation to Cytokine Levels in Ankylosing Spondylitis

Rheumatology and Therapy, 2019
Introduction Ankylosing spondylitis (AS) is a lifelong condition where spinal inflammation causes chronic back pain and restriction of spinal function.
Johannes C. Nossent, Sylvia Sagen-Johnsen, Gunnstein Bakland   +2 more
doaj   +1 more source

Targeting inflammatory pathways in axial spondyloarthritis. [PDF]

, 2019
The triggers and pathogenesis of axial spondyloarthritis (axSpA) are not yet completely understood. However, therapeutic agents targeting tumor necrosis factor-α and interleukin-17 inflammatory pathways have proven successful in suppressing many of the ...
Furst, Daniel E, Louie, James S
core  

Efficacy of Ixekizumab in Chinese Patients with Radiographic Axial Spondyloarthritis by Baseline C-Reactive Protein Level

Rheumatology and Therapy
Introduction Ixekizumab, an interleukin 17A inhibitor, improved the Assessment of SpondyloArthritis international Society 40 (ASAS40) response rates irrespective of baseline inflammation in international populations with radiographic axial ...
Ning Kong, Jiankang Hu, Dongzhou Liu, Jingyang Li, Huaxiang Wu, Lingyun Sun, Dai Lie, Chunyu Tan, Zhijun Li, Zhengyu Xiao, Cibo Huang, Jian Xu, Yan Yan, Hongying Li, Hejian Zou   +14 more
doaj   +1 more source

Impact of patient characteristics on ASDAS disease activity state cut-offs in axial spondyloarthritis: results from nine European rheumatology registries

RMD Open
Objectives To re-evaluate cut-offs for disease activity states according to the Axial Spondyloarthritis Disease Activity Score (ASDAS), and study the impact of sex, age, calendar time, disease and symptom duration on ASDAS and ASDAS cut-offs in a large ...
Bente Glintborg, Merete Lund Hetland, Tore K Kvien, Brigitte Michelsen, Dan Nordström, Karel Pavelka, Ziga Rotar, Maria Jose Santos, Anne Gitte Loft, Ana Rodrigues, Mikkel Østergaard, Jakub Zavada, Olafur Palsson, Bjorn Gudbjornsson, Adrian Ciurea, Michael J Nissen, Dilek Solmaz, Stylianos Georgiadis, Lykke M Ørnbjerg, Johan K Wallman, Anna Mari Hokkanen, Gökçe Kenar, Katja Perdan Pirkmajer, Simon Rasmussen, Daniela Di Guiseppe   +24 more
doaj   +1 more source

Sex-specific disparities in disease activity scores among patients with axial spondyloarthritis and their implications for evaluating the response to tumor necrosis factor alpha inhibitor therapy

Arthritis Research & Therapy
Background We aimed to investigate whether there are sex differences in disease activity measures among patients with axial spondyloarthritis (axSpA) and to determine any potential impact on the assessment of treatment responses to tumor necrosis factor ...
Seulkee Lee, Seonyoung Kang, Hyungjin Kim, Jaejoon Lee, Min-Ji Kim, Hoon-Suk Cha   +5 more
doaj   +1 more source

Evaluation of the presence of neuropathic pain and/or central sensitization in patients with radiographic axial spondyloarthritis followed at a tertiary hospital

Advances in Rheumatology
Background Chronic pain (CP) in radiographic Axial Spondyloarthritis (r-axSpA) is primarily peripheral nociceptive pain. However, many patients experience persistent pain despite treatment, suggesting other underlying mechanisms, such as central ...
Débora de Jesus Sena, Maria Nathalia Gabriela Rocha Pontes de Oliveira, Maria Roberta Melo Pereira Soares, Luís Fábio Barbosa Botelho, Alessandra de Sousa Braz   +4 more
doaj   +1 more source

Clinical Tools to Assess and Monitor Spondyloarthritis [PDF]

, 2015

core   +1 more source

Psychometric Properties of the Persian Version of the Evaluation of Ankylosing Spondylitis Quality of Life (EASi‐QoL) and Ankylosing Spondylitis Disease Activity Score (ASDAS) Questionnaires: A Cross‐Sectional Study

Health Science Reports
Background and Aims Ankylosing spondylitis (AS) is a chronic inflammatory disease that affects quality of life (QoL) due to its impact on physical and emotional well‐being.
Maryam Hosseini, Amirmasoud Kazemzadeh Houjaghan, Ghazal Behzad, Sahar Ghorbanpour, Seyede Zahra Emami Razavi, Mohaddeseh Azadvari, Shafieh Movaseghi, Negar Salaminour   +7 more
doaj   +1 more source