Results 31 to 40 of about 14,723 (146)

Phagocytic Mesothelial Cells in Pericardial Effusion Following Allogeneic Peripheral Blood Stem Cell Transplantation for Chronic Active Epstein–Barr Virus Infection: A Distinctive Cytomorphological and Immunocytochemical Case Study

open access: yesDiagnostic Cytopathology, EarlyView.
ABSTRACT Phagocytic activity of mesothelial cells is a rare phenomenon requiring careful differentiation from histiocytic hemophagocytosis to ensure appropriate patient management, as these phenomena could exhibit distinct clinical implications. In this study, we report a case of phagocytic mesothelial cells found in pericardial effusion that developed
Hidetoshi Satomi   +5 more
wiley   +1 more source

Mitigating Health Risks in French Fries: Understanding Acrylamide and Hydroxymethylfurfural Management Through Potato Variety and Storage Exploration

open access: yesFuture Postharvest and Food, EarlyView.
Strategic optimization of potato variety selection and storage conditions to control harmful compounds in French fries. Through systematic evaluation of three potato varieties stored under conditions upto 45 days, which demonstrated that Kufri Frysona variety stored for 15 days provides the best balance between minimizing health‐risk compounds and ...
Vandana Verma   +3 more
wiley   +1 more source

Identifikasi Bakteri Endofit Mangrove Api-Api Putih (Avicennia marina) Penghasil Enzim L-asparaginase
[Identification of Mangrove Endophyte Bacteria of Api-Api Putih (Avicennia marina) as Producing L-asparaginase Enzyme]

open access: yesJurnal Ilmiah Perikanan dan Kelautan, 2018
Enzim L-asparaginase (E.C 3.5.1.1) adalah protein tetramer yang termasuk dalam kelompok keluarga amidohydrolases homolog. ). L-asparaginase secara selektif menghidrolisis L-aspargin (L-Asn) menjadi amonia (NH3) dan asam aspartat. Penelitian ini bertujuan
Asep Awaludin Prihanto   +3 more
doaj   +1 more source

Systemic anti‐cancer therapy associated with the occurrence of peripheral neurotoxicity and, specifically, peripheral neuropathy

open access: yesInternational Journal of Cancer, EarlyView.
What's New? While the effectiveness of systemic anticancer therapy is well documented, it commonly causes severe toxicity. This study of the 467 systemic anticancer therapy agents currently approved globally for clinical and/or research purposes found that peripheral neurotoxicity is associated with 45% of classical chemotherapies, 21% of targeted ...
Cassie Higgins   +3 more
wiley   +1 more source

A Case of Cutaneous B Lymphoblastic Lymphoma With Multiple Cutaneous Tumors

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT A 17‐year‐old Japanese male patient was referred to our hospital due to an erythematous tumor on part of the right mandible that had developed 3 months earlier, and similar tumors had appeared on the trunk and lower extremities. A complete blood count showed no specific abnormalities.
Tomomichi Shimizu   +4 more
wiley   +1 more source

A Study on L-Asparaginase of Nocardia levis MK-VL_113

open access: yesThe Scientific World Journal, 2012
An enzyme-based drug, L-asparaginase, was produced by Nocardia levis MK-VL_113 isolated from laterite soils of Guntur region. Cultural parameters affecting the production of L-asparaginase by the strain were optimized.
Alapati Kavitha, Muvva Vijayalakshmi
doaj   +1 more source

Case report: Hyperosmolar hyperglycemic syndrome secondary to PEG-asparaginase-induced hypertriglyceridemia and pancreatitis

open access: yesFrontiers in Oncology, 2023
Pegylated (PEG)-asparaginase is an established treatment for acute lymphoblastic leukemias that exhibits an antitumor effect by depleting asparagine, an amino acid essential for leukemia cell protein synthesis. Pancreatitis with hypertriglyceridemia is a
Todd William Mudd   +3 more
doaj   +1 more source

Antithrombin: Deficiency, Diversity, and the Future of Diagnostics

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Our healthcare system provides reactive sick‐care, treating patients after symptoms have appeared by prescription of generic and often suboptimal therapy. This strategy brings along high costs and high pressure which is not sustainable.
Mirjam Kruijt   +2 more
wiley   +1 more source

Production of extracellular L- asparaginase by halophilic bacterium vibrio sp.

open access: yesBiological Journal of Microorganism, 2016
Introduction: L-Asparaginase is an anti-neoplastic drug used in lymphoblastic leukemia chemotherapy. Nowadays, this enzyme derived from bacterial sources, mostly L-asparaginase II from Escherichia coli and in lesser amount L-asparaginase of Erwinia sp ...
Mahdis Zolfaghar   +2 more
doaj  

The cost-effectiveness of pegaspargase versus native asparaginase for first-line treatment of acute lymphoblastic leukaemia: a UK-based cost-utility analysis

open access: yesHealth Economics Review, 2019
Background L-asparaginase is a key component of treatment for patients with acute lymphoblastic leukaemia (ALL) in the UK. Commonly used forms of asparaginase are native E.
Xingdi Hu   +5 more
doaj   +1 more source

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