Results 21 to 30 of about 20,129 (222)

Aspartame and Its Metabolites Cause Oxidative Stress and Mitochondrial and Lipid Alterations in SH-SY5Y Cells

open access: yesNutrients, 2023
Due to a worldwide increase in obesity and metabolic disorders such as type 2 diabetes, synthetic sweeteners such as aspartame are frequently used to substitute sugar in the diet.
L. V. Griebsch   +13 more
semanticscholar   +1 more source

Consumption of aspartame and other artificial sweeteners and risk of cancer in the Spanish multicase‐control study (MCC‐Spain)

open access: yesInternational Journal of Cancer, 2023
Use of artificial sweeteners (AS) such as aspartame, cyclamate, saccharin and sucralose is widespread. We evaluated the association of use of aspartame and other AS with cancer.
A. Palomar-Cros   +35 more
semanticscholar   +1 more source

Long-term aspartame and saccharin intakes are related to greater volumes of visceral, intermuscular, and subcutaneous adipose tissue: the CARDIA study

open access: yesInternational Journal of Obesity, 2023
Artificial sweetener (ArtSw) intakes have been previously associated with higher BMI in observational studies and may promote visceral and skeletal muscle adipose tissue (AT) accumulation.
B. Steffen   +9 more
semanticscholar   +1 more source

Effects of Tapak Dara Leaves Extract on Kidney Histology of Aspartame-Induced Mice

open access: yesBiosfer: Jurnal Tadris Biologi, 2021
This study aimed to determine the effect of Catharanthus roseus leaves extract on kidney histology of mice aspartame-induced. Mice were divided into 4 groups, namely the negative control group (K-) without treatment, the positive control (K+) given ...
Eva Tyas Utami   +2 more
doaj   +1 more source

Aspartame—True or False? Narrative Review of Safety Analysis of General Use in Products

open access: yesNutrients, 2021
Aspartame is a sweetener introduced to replace the commonly used sucrose. It was discovered by James M. Schlatter in 1965. Being 180–200 times sweeter than sucrose, its intake was expected to reduce obesity rates in developing countries and help those ...
Kamila Czarnecka   +6 more
semanticscholar   +1 more source

Does low-energy sweetener consumption affect energy intake and body weight? A systematic review, including meta-analyses, of the evidence from human and animal studies [PDF]

open access: yes, 2015
By reducing energy density, low-energy sweeteners (LES) might be expected to reduce energy intake (EI) and body weight (BW). To assess the totality of the evidence testing the null hypothesis that LES exposure (versus sugars or unsweetened alternatives ...
de Graaf, C   +10 more
core   +5 more sources

Daily Early-Life Exposures to Diet Soda and Aspartame Are Associated with Autism in Males: A Case-Control Study

open access: yesNutrients, 2023
Since its introduction, aspartame—the leading sweetener in U.S. diet sodas (DS)—has been reported to cause neurological problems in some users. In prospective studies, the offspring of mothers who consumed diet sodas/beverages (DSB) daily during ...
Sharon P Fowler   +5 more
semanticscholar   +1 more source

Perspectives on recent reviews of aspartame cancer epidemiology

open access: yesGlobal Epidemiology, 2023
Aspartame is a dipeptide non-sugar sweetener that was first marketed in the US in carbonated beverages in 1983, before gaining prominence globally. The Joint Food and Agriculture Organization of the United Nations (FAO)/World Health Organization (WHO ...
J. Goodman, D. Boon, Maia M. Jack
semanticscholar   +1 more source

Using PDMS Plasma Cavity SERS Substrate for the Detection of Aspartame

open access: yesJournal of Spectroscopy, 2020
Surface-enhanced Raman spectroscopy (SERS) was used to simply and sensitively detect the artificial sweetener aspartame added to purified water. In this paper, a cavity formed spontaneously by silver ion droplets, and liquid polydimethylsiloxane (PDMS ...
Lvming Chen   +10 more
doaj   +1 more source

The neuroprotective potential of turmeric rhizome and bitter melon on aspartame-induced spatial memory impairment in rats

open access: yesHeliyon, 2023
Aspartame is widely used artificial sweetener. However, chronic exposure to aspartame led to spatial memory impairment and elevated oxidative stress in the brain.
Vicko Suswidiantoro   +5 more
doaj   +1 more source

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