Results 161 to 170 of about 467,415 (311)

Artificial Intelligence‐Based Body Composition Analysis Reveals Sex‐Specific Prognostic Markers and Their Clinical Value in Gastric Cancer: A Multicenter Study

Advanced Science, EarlyView.
This study applied AI to quantify multidimensional body composition from CT images in gastric cancer and healthy controls. Distinct sex‐specific patterns and disease‐related alterations were identified and were associated with survival. Higher muscle and fat measures were linked to improved outcomes.
Tianxiang Li, Tingting Liu, Qian Yang, Zhiqing Zhang, Xiaofang Guo, Xiang Wang, Yihan Zhang, Limin Ge, Yu Su, Wenjun Wu, Weihua Guo, Zheng Wang, Lian Yang, Yanfeng Niu   +13 more
wiley   +1 more source

Biochemical Studies on the Aspartate Aminotransferase from Deinococcus radiodurans R1

, 2007
耐輻射奇異球菌（Deinococcus radiodurans R1；D. radiodurans R1）對於環境中的游離輻射、UV輻射與過氧化氫的抵抗力極高。瞭解D. radiodurans R1所擁有的特殊分子及生理層次可以幫助我們認識生物體應對輻射傷害而發展的耐受機制。本研究主要為探討耐輻射奇異球菌之天門冬胺酸轉胺酶 (Aspartate Aminotransferase；AspAT；EC 2.6.1.1）的各項性質。 天門冬胺酸轉胺酶也稱為麩胺酸-草乙酸轉胺酶（Glutamate ...
徐于婷, Hsu, Yu-Ting
core  

Recent advances in nonprotein amino acids: insights from function to biosynthesis. [PDF]

J Anim Sci Biotechnol
Zou Y, Jiang X, Li N, Zhong S, Zhang S, Ji Y, Yu H, Zeng X, Deng A, Qiao S.   +9 more
europepmc   +1 more source

SuFEx‐Enabled Reprogramming of Flavonoids for Selective α‐Glucosidase Covalent Inhibition

Advanced Science, EarlyView.
Selective inhibition of intestinal α‐glucosidase remains limited by poor enzyme specificity and off‐target metabolic effects. Here, SuFEx click chemistry is used to reprogram natural flavonoids into covalent inhibitors with enhanced α‐glucosidase selectivity and controlled reactivity. This strategy enables effective regulation of carbohydrate digestion
Fengyu Guo, Liwei Zhang, Minlong Wang, Yanjin Du, Tianyu Zhang, Hao Chen, Jiazeng Sun, Yang Yu, Zude He, Jie An, Xiaoxu Zhang, Weilin Lin, Fazheng Ren, Pengjie Wang, Ping Liu   +14 more
wiley   +1 more source

Renal metabolism of hyperpolarized [1-13C]aspartate

Aspartic acid is involved in several central metabolic pathways, including gluconeogenesis, the urea cycle, de novo nucleotide synthesis, the malate-aspartate shuttle, and via transmination the TCA cycle.
Yoshihara, Hikari A. I., Schwitter, Juerg   +1 more
core  

Oncolytic virus hijacks GOT1 and pyrimidinosomes to fuel pyrimidine synthesis for replication in tumor cells. [PDF]

Tumour Virus Res
Tang N, Gong Y, Zhao C, Niu Y, Tan L, Song C, Qiu X, Liao Y, Yu S, Ding C, Lin S, Sun Y.   +11 more
europepmc   +1 more source

L-Aspartate and Microproteinuria [PDF]

Nephron, 2008
L, Odum, G, Hansen-Nord, C A, Nielsen
openaire   +2 more sources

Sodium Ascorbate‐Accelerated Gelling Hydrogels With Rapid Self‐Mineralized Capacity for Chronic Wounds

Advanced Science, EarlyView.
An immunoregulatory hydrogel based on sodium ascorbate (SA)‐accelerated gelation and in situ self‐mineralization is prepared here. Such a hydrogel is constructed by mixing benzaldehyde‐ and cyanoacetate‐functionalized dextran with silver nitrate (AgNO3) and SA, enabling the ultrafast solidification and in situ self‐mineralization of silver ...
Xiaoya Ding, Wei Yang, Wenzhao Li, Guifang Xu, Yuanjin Zhao   +4 more
wiley   +1 more source

Aspartate aminotransferase is required for <i>Salmonella</i> expansion in the inflamed gut via TCA anaplerosis. [PDF]

Infect Immun
Shealy NG, Baltagulov M, Avalos HF, Olivas J, Jones KM, Byndloss MX.   +5 more
europepmc   +1 more source

Glutamic Aspartic Transaminase

Journal of Biological Chemistry, 1957
W. Terry Jenkins, Irwin W. Sizer
openaire   +1 more source