Results 211 to 220 of about 572,945 (313)

AGC1/2, the mitochondrial aspartate-glutamate carriers.

Biochimica et Biophysica Acta, 2016
N. Amoedo, N. Amoedo, G. Punzi, G. Punzi, É. Obre, Didier Lacombe, A. D. Grassi, C. Pierri, Rodrigue Rossignol   +8 more
semanticscholar   +1 more source

Mucoadhesive Peptide‐Catalase Self‐Assembled Nano‐Formulation for Effective Treatment of Mucosal Inflammatory Diseases

Advanced Science, EarlyView.
CR8L10 is self‐assembled with catalase (CAT) to form CR8L10@CAT nanocomplexes, which can anchor to mucosal surfaces via thiol‐disulfide exchange with mucin, thereby enhancing their mucosal retention. The efficient reactive oxygen species (ROS) scavenging at inflamed sites would then result in successful treatment in both the intravesical IC/BPS model ...
Xinzhu Li, Yuxuan Ma, Di He, Yingying Huang, Yutong Jiang, He Zhao, Shengjie Ge, Ruirui Zhao, Hejia Yuan, Wendi Jiang, Wenjun Zhu, Kai Liu, Han Zhang, Zhuang Liu   +13 more
wiley   +1 more source

Assessment of fibrosis in chronic hepatitis B using APRI, FIB-4, FIB-5, FIB-6, and S-Index: Comparison with histology. [PDF]

Medicine (Baltimore)
Kahramanoğlu Aksoy E, Ayte MR, Çobanoğlu H, Korlaelçi F, Aktaş B, Özgül S, Kaplan Yilmaz MB, Albayrak HC, Arabaci S, İzmirlioğlu K, Uzman M.   +10 more
europepmc   +1 more source

Gene Correction Enhances Dopaminergic Cell Therapy in a Nonhuman Primate Model of Parkinson's Disease

Advanced Science, EarlyView.
LRRK2‐mutant induced pluripotent stem cells (iPSCs) were derived from a patient with Parkinson's disease (PD). Using CRISPR/Cas9–mediated gene editing, the pathogenic LRRK2 mutations were precisely corrected, and isogenic dopaminergic neural progenitor cells (DA‐NPCs) were subsequently generated.
Qing Yan, Chongchong Xu, Jiangmei Gao, Pu Wang, Qingling Wu, Ying Jin, Binyan Lu, Mu Li, Mingting Shao, Bihai Li, Zhenghui Su, Yijng Zhang, Jianhuan Chen, Haojie An, Mengyao Huang, Xiaoji Zhuang, Yuhui Shen, Fenglin Wang, Nana Xu, Yiyan Liu, Lei Tang, Xiuling Zhong, Minyan Zhong, Jiecong Chen, Zhenhuang Wang, Xingrong Luo, Sheng Liu, RuiFeng Liu, Ling Zhang, Junhua Rao   +29 more
wiley   +1 more source

When 'Liver Enzymes' Are Not Hepatic: Late-Onset Pompe Disease. [PDF]

Med J Aust
Madigan S, England G, Rankin W.
europepmc   +1 more source

Glutamic-Aspartic Transaminase

Journal of Biological Chemistry, 1961
openaire   +1 more source

Liver Endothelia Orchestrate MASH‐Associated Macrophage Zonation Through FSTL1‐ITGA4 Axis

Advanced Science, EarlyView.
Liver inflammation in MASH fundamentally hinges on the newly defined Kit/STAT2/FSTL1/ITGA4 axis. Declining endothelial Kit collapses normal hepatic zonation, driving an aberrant FSTL1 gradient that recruits pathogenic macrophages. Strikingly, targeting FSTL1‐ITGA4 with anti‐VLA4 restores spatial immune homeostasis and halts disease progression ...
Lin Sun, Zhensheng Yue, Zhiqiang Fang, Hao Xu, Wei Du, Yuwei Ling, Jingjing Liu, Ping Song, Fei He, Juanli Duan, Lin Wang   +10 more
wiley   +1 more source

The outcome of Infliximab induction in patients with severe ulcerative colitis may be related to intestinal microbiota. [PDF]

Front Microbiol
Chen J, Zhou Q, Cao X, Jin S, Wu Y, Ren T, Xu C, Chen H, Zhang H, Zhang Y, Liu J.   +10 more
europepmc   +1 more source

Psychological Stress Associated Bile Acid Reprogramming Promotes Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
Depression is increasingly recognized as a risk factor for chronic diseases, yet its biological impact on cancer remains unclear. Using data from more than 490 000 participants across three international cohorts, we show that depression significantly increases the risk of liver cancer.
Ruijiang Zeng, Mengmeng Wang, Kang Wang, Zhuo Xing, Yulong Hong, Tongtong Li, Geng Zong, Chong Yang, Dan Zhang, Zhangling Chen, Xin Jin   +10 more
wiley   +1 more source

Serum matrix metalloproteinase-7 as a diagnostic and prognostic biomarker in primary biliary cholangitis. [PDF]

Front Med (Lausanne)
Chen J, Shang X, Peng C, Wang L, Zhang N, Lu W, Liu M.   +6 more
europepmc   +1 more source