Results 241 to 250 of about 572,945 (313)

Effects of SGLT-2 inhibitors and GLP-1 receptor agonists on liver function in patients with non-alcoholic fatty liver disease and type 2 diabetes. [PDF]

Front Endocrinol (Lausanne)
Guo W, Li W, Li X, Shi W, Yan Y, Yan T, Zhou J, Huang Y.   +7 more
europepmc   +1 more source

Neuron‐Targeted Exosomal Delivery of siRNA Against RIPK3 Slows Neurodegenerative Progression in Alzheimer's Disease

Advanced Science, EarlyView.
Engineered exosomal siRNA delivery platform enables systemic, neuron‐targeted RNA transport across the blood–brain barrier. Surface functionalization with rabies virus glycoprotein‐derived peptide facilitates receptor‐mediated transcytosis, achieving efficient cytosolic delivery and robust gene silencing. Targeting RIPK3 suppresses necroptosis, reduces
Chi Zhang, Jiaqi Zhang, Yuzhi Wang, Yaodong Wang, Peng Lin, Yanling Wang, Zixuan Tang, Jintai Yu, Qin Zhou, Feiyun Cui   +9 more
wiley   +1 more source

A Cross-Sectional Observational Study of Non-alcoholic Fatty Liver Disease Assessed by Fibrosis Index in Patients With Type 2 Diabetes Mellitus Presenting to a Tertiary Care Centre in Southwestern Maharashtra. [PDF]

Cureus
Patil PU, Patange AP, Aundhakar S, Patil UV.   +3 more
europepmc   +1 more source

Follow-up of jaundice-free biliary atresia survivors using M2BPGi and APRI in a local hospital. [PDF]

World J Pediatr Surg
Shirai T, Okuya S.
europepmc   +1 more source

Evaluation of the APRI score and blood-count-derived inflammatory markers in patients with preeclampsia. [PDF]

BMC Pregnancy Childbirth
Taş BÖ, Soysal C, Bıyık İ, Ulaş Ö, Taşçı Y.   +4 more
europepmc   +1 more source

Conformational Dynamics of Plasmepsin X during Inhibitor Binding. [PDF]

J Phys Chem B
Karubiu W, Kullmann R, Krummhaar M, Roth C, Weikl TR.   +4 more
europepmc   +1 more source

Functional profiling of 2,193 ASS1 missense variants: Insights into variant pathogenicity and epistatic interactions in citrullinemia type I. [PDF]

PLoS Genet
Lo RS, Cromie GA, Tang M, Sirr A, Caldovic L, Morizono H, Ah Mew N, Gropman A, Dudley AM.   +8 more
europepmc   +1 more source

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Metabolic engineering of Escherichia coli for production of L-aspartate and its derivative β-alanine with high stoichiometric yield

Metabolic Engineering, 2019
L-aspartate is an important 4-carbon platform compound that can be used as the precursor of numerous chemical products. The bioproduction of L-aspartate directly from biomass resources is expected to provide a more cost-competitive technique route.
Yong Tao, Baixue Lin, Lei Wang
exaly   +2 more sources

Insulin Aspart

Drugs, 1999
Insulin aspart is a recombinant analogue of human insulin. Following subcutaneous insulin injection (0.15 to 0.2 U/kg), significantly higher serum insulin concentrations are achieved in a shorter time with insulin aspart than with human insulin. The subsequent decline in serum insulin concentrations is also more rapid with insulin aspart.
K L, Simpson, C M, Spencer
openaire   +2 more sources