Results 121 to 130 of about 192,345 (324)

Toxicological evaluation of the effect of phenol-contaminated water on the liver of albino rats

open access: yesCHRISMED Journal of Health and Research, 2015
Phenol is a constituent of coal tar and is formed during the natural decomposition of organic materials. The effect of phenol-contaminated water on the liver of rats was investigated.
Aanuoluwa James Salemcity   +3 more
doaj   +1 more source

Potent and Long‐Lasting Immunogenicity Generated by LNP‐mRNA gE Antigen Against Varicella Zoster Virus via an AI‐Assisted Pipeline

open access: yesAdvanced Science, EarlyView.
This study designs a novel mRNA‐LNP vaccine targeting VZV glycoprotein E (gE) for herpes zoster via an AI‐assisted pipeline. Validated in mice and rhesus macaques, the mRNA‐LNP vaccine shows strong humoral and cellular immune responses, with CD4+ T‐cell responses more effective and durable than Shingrix, offering a promising prophylactic option ...
Kai Dong   +6 more
wiley   +1 more source

Novel Vascularized Human Liver Organoids for Modeling Alcohol‐Induced Liver Injury and Developing Hepatoprotective Therapy

open access: yesAdvanced Science, EarlyView.
This study successfully engineered vascularized liver organoids (3HLOs) by co‐culturing human reprogrammed hepatocyte‐like cells (hrHLs) with human umbilical vein endothelial cells (HUVECs) and human umbilical mesenchymal stem cells (HUMSCs). Upon implantation, the 3HLOs established functional vascular anastomosis with the host circulation and ...
Kangdi Yang   +13 more
wiley   +1 more source

Seasonal Variations of some Hematological and Biochemical Parameters of the Carpathian Romanian Buffaloes. I. The Winter Period

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
Aim of this study was to investigate the blood parameters in Carpathian Romanian Buffaloes in order to establish their physiological ranges. Eight buffaloes from Şercaia-Braşov area were screened for hematological and biochemical profile during the ...
Maria Serdaru   +4 more
doaj  

A note on the prothrombin time abnormality in the patients with amebic liver abscess [PDF]

open access: yes, 2006
Amebic liver abscess is reported worldwide and can present with a a wide spectrum of clinical manifetations. Similar to the other liver diseases, the prothrombin time abnormality can be seen in the patients with amebic liver abscess.
Suwansaksri, Jamsai   +2 more
core   +1 more source

Long-term safety of siltuximab in patients with idiopathic multicentric Castleman disease: a prespecified, open-label, extension analysis of two trials. [PDF]

open access: yes, 2020
BACKGROUND:Siltuximab is recommended by international consensus as a first-line treatment for idiopathic multicentric Castleman disease on the basis of durable efficacy and safety data.
Casper, Corey   +6 more
core  

Nuclear Factor I‐B Delays Liver Fibrosis by Inhibiting Chemokine Ligand 5 Transcription

open access: yesAdvanced Science, EarlyView.
This study identifies the transcription factor Nuclear Factor I‐B (NFIB) as a key suppressor of liver fibrosis. NFIB expression declines during hepatic stellate cell activation, and its overexpression reduces fibrosis in mice models. The mechanism involves NFIB directly repressing chemokine C─C motif ligand 5 (CCL5), thereby alleviating oxidative ...
Qianqian Chen   +14 more
wiley   +1 more source

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