Results 191 to 200 of about 5,130,397 (333)

Shifting the Substrate Scope of an Ene/Yne‐Reductase by Loop Engineering

open access: yesChemCatChem, EarlyView.
A flexible active‐site loop that is involved in shaping the substrate and product cleft as well as the active‐site pocket was identified for the MDR‐related ene/yne‐reductase CaeEnR1 from Cyclocybe aegerita. Double mutations of this loop showed an up to 20‐fold increase in conversion rates toward cinnamaldehyde‐like substrates and a 2‐fold increase in ...
Dominik Karrer   +7 more
wiley   +1 more source

Synergistic Effect of Bio‐Inspired Microenvironment Modulation and Catalytic Site Design Enhances the Oxygen Evolution Performance of Copper‐Phenanthroline Catalysts

open access: yesCarbon Energy, EarlyView.
Bio‐inspired by natural Cu‐His active centres, His‐functionalized CDs was used to support copper catalysts, which enable high catalytic TOFs of (2.80 ± 0.12) × 103 and (4.11 ± 0.24) × 104 s−1, respectively, exceeding the activity of natural photosystem II.
Mu‐Han Zhou   +9 more
wiley   +1 more source

Conserved Phosphorylation of the Myosin1e TH1 Domain Impacts Membrane Association and Function in Yeast and Worms

open access: yesCytoskeleton, EarlyView.
ABSTRACT Cells have an intrinsic ability to rapidly respond to environmental change to regulate cell cycle progression and membrane organisation, thereby affecting cell growth and division. The actin cytoskeleton is a highly dynamic complex of proteins that can rapidly reorganise to change the growth pattern of a cell.
Holly R. Brooker   +7 more
wiley   +1 more source

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