Results 181 to 190 of about 138,442 (297)

Metabolic profiling reveals channeled de novo pyrimidine and purine biosynthesis fueled by mitochondrially generated aspartic acid in cancer cells. [PDF]

Nat Commun
Pareek V, Benkovic S.
europepmc   +1 more source

Levodopa-induced dyskinesia: interplay between the N-methyl-D-aspartic acid receptor and neuroinflammation. [PDF]

Front Immunol, 2023
Zhang F, Liu M, Tuo J, Zhang L, Zhang J, Yu C, Xu Z.   +6 more
europepmc   +1 more source

Interplay of Ser273 Phosphorylation and K268 and K293 Acetylation in PPARγ: Implications for PPARγ Activation

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Post‐translational modifications (PTMs) play a critical role in regulating the transcriptional activity of PPARγ, a nuclear receptor central to glucose and lipid homeostasis. Among these, lysine acetylation at K268 and K293 and phosphorylation at S273 are particularly relevant to insulin sensitivity.
Caique Camargo Malospirito, Marieli Mariano Gonçalves Dias, Gabriel Ernesto Jara, Thayná Mendonça Avelino, Giovanna Blazutti Elias, Paulo Sergio Lopes de Oliveira, Ana Carolina Migliorini Figueira   +6 more
wiley   +1 more source

Tuning the Swelling Behavior of Superabsorbent Hydrogels with a Branched Poly(aspartic acid) Crosslinker. [PDF]

Gels
Shin S, Kim S, Hong S, Kim N, Kang J, Jeong J.   +5 more
europepmc   +1 more source

Analysis of glutamine synthetase target‐site mutations and their role in endowing glufosinate‐ammonium resistance

Pest Management Science, EarlyView.
GS2.2 G255D mutation conferred enzyme‐level glufosinate insensitivity but no whole‐plant resistance, showing trade‐offs between catalytic function and herbicide binding and providing a baseline for future studies on target‐site glufosinate resistance.
Aimone Porri, Susee Sudhakar, Matheus M Noguera, Michael Betz, Jens Lerchl, Franck E Dayan, Ingo Meiners, Tino Caldarelli, Jason Norsworthy   +8 more
wiley   +1 more source

M13 phages engineered with chlamydia phage φCPG1 protein IN5 and arginine-glycine-aspartic acid inhibits Chlamydia trachomatis intracellular growth. [PDF]

Virus Res
You C, Wang M, Wang J, Lian T, Liu Q.
europepmc   +1 more source

Flavonoids in Nasal Therapeutics: Biological Activities, Delivery Challenges, and Formulation Strategies–A Systematic Review

Phytotherapy Research, EarlyView.
Overview of the therapeutic potential of flavonoids in nasal delivery systems, highlighting their benefits to the human nasal cavity, and applications in the treatment of respiratory and brain‐related diseases. ABSTRACT Flavonoids represent a significant group of secondary metabolites.
Jeniffer Viviana Ramirez Hernández, Sara Elis Bianchi, Flávia Nathiely Silveira Fachel, Elizandra Braganhol, Sheila Porto de Matos, Valquíria Linck Bassani   +5 more
wiley   +1 more source

Atomic scale insight into the adsorption mechanism of aspartic acid on Ti-6Al-4V dental implants: a combination of DFT and AIMD. [PDF]

BMC Oral Health
Yang Y, Wang JN, Hu LX, Qasim Q, Liu XC, Xu W.   +5 more
europepmc   +1 more source

Preclinical Evaluation of Berry Extracts as a Nutritional Intervention to Alleviate Myocardial Ischemia–Reperfusion Injury and Atherosclerosis Development

Phytotherapy Research, EarlyView.
Schematic representation of the experimental design and the proposed mechanisms underlying the cardioprotective and anti‐atherosclerotic effects of Greek‐derived berry extracts. C57BL/6 mice with WD–induced MS and ApoE−/− mice with atherosclerosis received chronic supplementation with WMex or BBex.
Lydia Symeonidi, Panagiota‐Efstathia Nikolaou, Panagiotis Stathopoulos, Andriana Christodoulou, Alexandra Svouraki, Panagiotis Efentakis, Christina Chania, Angeliki Choustoulaki, Maria Xenaki, Anna Agapaki, Maria Tsoumani, Nikolaos Kostomitsopoulos, Ioulia Tseti, Gemma Vilahur, Alexios‐Leandros Skaltsounis, Ioanna Andreadou   +15 more
wiley   +1 more source

Aspartic acid residues in BBE-like enzymes from <i>Morus alba</i> promote a function shift from oxidative cyclization to dehydrogenation. [PDF]

Proc Natl Acad Sci U S A
Guo N, Gu J, Zhou Q, Liu F, Dong H, Ding Q, Wang Q, Wu D, Yang J, Fan J, Gao L, Houk KN, Lei X.   +12 more
europepmc   +1 more source