Results 261 to 270 of about 5,130,397 (333)

19F NMR Relaxometry and Diffusometry for Measuring Cargo Molecule Dynamics in GelMA Hydrogels

Macromolecular Materials and Engineering, EarlyView.
In this research, fluorine drug dynamics in GelMA hydrogels are measured through fluorine‐19 nuclear magnetic resonance (19F NMR) relaxometry and diffusometry. By combining the Solomon–Bloembergen equations and the Stokes–Einstein–Debye relationship, the microscopic dynamic information includes in situ interaction between drugs and polymer networks ...
Chun‐Wei Chang, Bronwin L. Dargaville, Konstantin I. Momot, Dietmar W. Hutmacher   +3 more
wiley   +1 more source

Characterization of ADA‐GEL Based Hydrogels Combined with Mesoporous Bioactive Glass Nanoparticles (MBGNs) and Human Platelet Lysate (HPL) for 3D (Bio)Printing

Macromolecular Materials and Engineering, EarlyView.
Alginate dialdehyde (ADA)‐gelatin (GEL) hydrogels are supplemented with mesoporous bioactive glass nanoparticles (MBGNs) and human platelet lysate (HPL) to enhance the biological performance of 3D printed scaffolds. Improved printability and higher shape fidelity are observed by incorporating 0.1% (w/v) MBGNs.
Yijun Zhao, Faina Bider, Aldo R. Boccaccini   +2 more
wiley   +1 more source

Effect of Photoinitiation Process on Photo‐Crosslinking of Gelatin Methacryloyl Hydrogel Networks

Macromolecular Rapid Communications, EarlyView.
A systematic comparison of three widely used photoinitiator systems, Eosin Y, LAP, and Ruthenium/SPS, reveals how their distinct radical‐generation mechanisms influence the stiffness, degradation, swelling, and cytocompatibility of GelMA hydrogels. This study uncovers initiator‐specific thresholds and network features critical for optimizing visible ...
Doğukan Duymaz, İsmail Can Karaoğlu, Seda Kizilel   +2 more
wiley   +1 more source

Self‐Immolative Polyion Complexes

Macromolecular Rapid Communications, EarlyView.
Polyion complexes (PICs) prepared by combining self‐immolative polymers (SIPs) with complementary charges are described. The polyanionic SIP is depolymerized at mildly acidic pH, while the polycationic SIP can be depolymerized upon irradiation with light.
Xueli Mei, Elizabeth R. Gillies
wiley   +1 more source

Glucose-6-phosphate dehydrogenase alleviates epileptic seizures by repressing reactive oxygen species production to promote signal transducer and activator of transcription 1-mediated N-methyl-d-aspartic acid receptors inhibition. [PDF]

Redox Biol
Hu L, Liu Y, Yuan Z, Guo H, Duan R, Ke P, Meng Y, Tian X, Xiao F.   +8 more
europepmc   +1 more source

Origin and characterization of cyclodepsipeptides: Comprehensive structural approaches with focus on mass spectrometry analysis of alkali‐cationized molecular species

Mass Spectrometry Reviews, EarlyView.
Abstract Cyclodepsipeptides (CDPs) represent a huge family of chemically and structurally diverse molecules with a wide ability for molecular interactions. CDPs are cyclic peptide‐related natural products made up of both proteinogenic and nonproteinogenic amino acids linked by amide and ester bonds.
Sophie Liuu, Annelaure Damont, Alain Perret, Olivier Firmesse, François Becher, Gwenaëlle Lavison‐Bompard, Amandine Hueber, Amina S. Woods, Ekaterina Darii, François Fenaille, Jean‐Claude Tabet   +10 more
wiley   +1 more source

Recent Advancements in the Characterization of D‐Amino Acid and Isoaspartate Post‐Translational Modifications

Mass Spectrometry Reviews, EarlyView.
ABSTRACT One of the great triumphs of mass spectrometry‐based peptide and protein characterization is the characterization of their modifications as most modifications have a characteristic mass shift. What happens when the modification does not change the mass of the peptide?
Samuel Okyem, Jonathan V. Sweedler
wiley   +1 more source

Practical Applications of Secondary/Extractive Electrospray Ionization (SESI): A Versatile Tool for Real‐Time Chemical Analysis

Mass Spectrometry Reviews, EarlyView.
ABSTRACT In the 1980s, researchers discovered the remarkable ability of electrospray plumes to effectively ionize gas‐phase molecules via secondary ionization. Around 20 years later—coinciding with the ambient mass spectrometry revolution—secondary electrospray ionization (SESI) and extractive electrospray ionization (EESI) coupled to mass spectrometry
Xin Luo, Huiling Wang, Xiaolan Hu, Sasho Gligorovski, Xue Li, Pablo Sinues   +5 more
wiley   +1 more source

Targeting Histone H3K9 Methyltransferase G9a as a Potential Therapeutic Strategy for Neuropsychiatric Disorders

Medicinal Research Reviews, EarlyView.
ABSTRACT Neuropsychiatric disorders present a multifaceted challenge, characterized by cognitive, social, and motor impairments with manifold underlying mechanisms. Recent attention has turned to epigenetic mechanisms, particularly histone lysine methyltransferases (HKMTs), such as G9a, in understanding fundamental pathogenesis.
Malak Hajar, Tobias Werner, Mihajlo Gajic, Holger Stark, Bassem Sadek   +4 more
wiley   +1 more source

Partially Biobased Self‐Repairing Poly(Aspartic Ester Polyurea) Coatings

Polymer Engineering &Science, EarlyView.
Sustainable self‐healing PAEU coatings, containing various amounts of disulfide derived from poly(aspartic esters) and biobased polyisocyanates, were created. ABSTRACT Poly(aspartic ester polyurea) (PAEU) coating systems, which feature an uncatalyzed and solventless reaction, have attracted attention as a more environmentally friendly, nonreactive ...
Sevilay Dural, Sebnem Camadanlı, Nilhan Kayaman Apohan   +2 more
wiley   +1 more source