Results 71 to 80 of about 5,130,397 (333)

Asymmetric Strategies for the Synthesis of Enantiopure α‐/β‐/γ‐Thio‐Carboxylic Acids Bearing a Stereocentre at CS Bond

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
Enantioenriched α‐/β‐/γ‐thiocarboxylic acids featuring C–S chirality are valuable targets in organic synthesis. This review outlines recent progress in their asymmetric synthesis, including chiral pool approaches, metal‐ /organo‐catalysis, and emerging biocatalytic strategies. Enantiomerically pure α‐/β‐/γ‐thiocarboxylic acids bearing a stereocentre at
Jingyue Wu, Daniele Castagnolo
wiley   +1 more source

Thermal Synthesis of Polypeptides from N-Butyloxycarbonyl Oligopeptides Containing Aspartyl Residue at C-Terminus

open access: yesInternational Journal of Polymer Science, 2017
The thermal reactions of amino acids have been investigated for pure organic synthesis, materials preparation in industry, and prebiotic chemistry. N-t-Butyloxycarbonyl aspartic acid (Boc-Asp) releases 2-butene and carbon dioxide upon heating without ...
Toratane Munegumi, Takafumi Yamada
doaj   +1 more source

Aspartic Acid Decarboxylase in Bacteria.

open access: yesExperimental Biology and Medicine, 1950
SummaryOf 16 strains of microorganisms studied, 7 exhibited positive aspartic acid decarboxylase activity. employing Rh. trijolii this enzyme was found to be stable to vacuum drying, and active cell-free juices could be prepared.
Walter E. David, Herman C. Lichstein
openaire   +2 more sources

LincNEAT1 Encoded‐NEAT1‐31 Promotes Phagocytosis by Directly Activating the Aurora‐A–PI3K–AKT Pathway

open access: yesAdvanced Science, EarlyView.
LincNEAT1 Encoded‐NEAT1‐31 micropeptide directly binds with Aurora‐A and enhanced AKT pathways to pormotes phagocytosis against multi cancer cells. Abstract Macrophages play vital roles in innate and adaptive immunity, and their essential functions are mediated by phagocytosis and antigen presentation.
Jie Li   +8 more
wiley   +1 more source

The Equilibrium between l-Aspartic Acid, Fumaric Acid and Ammonia in Presence of Resting Bacteria.

open access: yesBiochemical Journal
IT is an old observation that when fumaric acid, maleic acid or malic acid is heated in the presence of ammonia in a sealed tube to 2000 a conversion to aspartic acid occurs.
J. H. Quastel, Barnet Woolf
semanticscholar   +1 more source

Piezoelectric Biomaterials for Bone Regeneration: Roadmap from Dipole to Osteogenesis

open access: yesAdvanced Science, EarlyView.
Piezoelectric biomaterials convert mechanical forces into electrical signals, offering novel strategies to restore and modulate bone microenvironments for tissue engineering. This review examines molecular dipole origins, spatial arrangements, and pseudo‐piezoelectric mechanisms and highlights dipole‐engineering techniques for osteogenesis regulation ...
Xiyao Ni   +7 more
wiley   +1 more source

Phosphorylation‐Dependent Stabilization of Collaborator of ARF (CARF) Suppresses Lymphoma Cell Proliferation

open access: yesAdvanced Science, EarlyView.
This study revealed that oncogene Collaborator of ARF (CARF) is closely related to B‐cell lymphoma tumorigenesis, and shares a conserved mechanism regulating protein stability with Arabidopsis Kip‐Related Protein6 (KRP6) through casein kinase 1‐mediated phosphorylation. Reduced phosphorylation led to the enhanced protein stability of CARF, resulting in
Li Qu   +7 more
wiley   +1 more source

ON APPLICATION OF ACETYLAMINOSICCINE ACID IN NEUROPEDIATRICS

open access: yesВопросы современной педиатрии, 2008
The article focuses on theoretical and practical aspects of using acetylaminosuccinic acid (cogitum) in neuropediatrics. General properties of amino acid drugs were discussed.
V.M. Studenikin   +2 more
doaj   +2 more sources

PEPTIDE SOLUBILITY, STRUCTURE AND CHARGE POSITION EFFECT ON ADSORPTION BY ALUMINIUM HYDROXIDE

open access: yesRevista Colombiana de Química, 2008
Solubility, structure and position of charges in a peptide antigen sequence can be mentioned as being amongst the basic features of adsorption. In order to study their effect on adsorption, seven analogue series were synthesized from a MSP-1 peptide ...
Mary Trujillo   +2 more
doaj  

Dysfunctional Decidual CD4+T Cells Induce Recurrent Pregnancy Loss via Palmitoylation‐Dependent Tim‐3 Lysosomal Sorting and Degradation

open access: yesAdvanced Science, EarlyView.
Dysfunctional decidual CD4+T cells induce recurrent pregnancy loss via palmitoylation‐dependent Tim‐3 lysosomal sorting and degradation. The integrated bioinformatics, proteomic, functional and model studies elucidate that Tim‐3 is palmitoylated by ZDHHC3 at Cys9. Sortilin bound to and directed palmitoylated Tim‐3 toward lysosome degradation, resulting
Liyuan Cui   +6 more
wiley   +1 more source

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