Results 61 to 70 of about 2,639,770 (286)
Aberrant amino acid metabolism promotes neurovascular reactivity in rosacea
JCI Insight, 2022 Rosacea is a chronic skin disorder characterized by abnormal neurovascular and inflammatory conditions on the central face. Despite increasing evidence suggesting that rosacea is associated with metabolic disorders, the role of metabolism in rosacea ...
Tangxiele Liu +10 more
doaj +1 more source
Spheroid‐On‐A‐Drop: A Modular Droplet Microfluidics Platform
Advanced Materials Technologies, EarlyView.The proposed Spheroid‐on‐a‐Drop platform represents a reproducible and tunable platform for the fabrication of biocompatible GelMA‐based microgels, able to support controlled 3D tumor spheroid culture. Its precise control over droplet dynamics and cell distribution paves the way for advanced applications in tissue modeling, drug screening, and ...
A. Fergola +8 more
wiley +1 more source
NH2-terminal amino acids of the serum lipoproteins of normal and hypercholesterolemic rabbits*
Journal of Lipid Research, 1960 Aspartic acid is the major and glutamic acid and serine are minor NH2-terminal amino acids of the lipoproteins of rabbit serum. No NH2-terminal amino acids other than these are found after prolonged cholesterol feeding.
B. Shore, V. Shore
doaj +1 more source
Targeting WDR12 Unleashes T‐Cell‐Mediated Antitumor Activity in Melanoma by Destabilizing CD276
Advanced Science, EarlyView.WDR12 cooperates with the chaperonin subunit CCT7 to maintain CD276 stability on tumor cells, suppressing T‐cell activity and promoting immune escape. SU14813, a small‐molecule WDR12 inhibitor, reduces CD276 stability and relieves CD276‐mediated T‐cell suppression.
Jie Pan +10 more
wiley +1 more source
Journal of Saudi Chemical Society, 2011 The cellular amino acid profiles of nine species of Fusarium; namely, Fusarium anthophilum, Fusarium avenaceum, Fusarium cerealis, Fusarium graminearum, Fusarium graminum, Fusarium oxysporum f. sp.
M.E. Zain +2 more
doaj +1 more source
Identification of a Tumor Specific, Active-Site Mutation in Casein Kinase 1α by Chemical Proteomics. [PDF]
PLoS ONE, 2016 We describe the identification of a novel, tumor-specific missense mutation in the active site of casein kinase 1α (CSNK1A1) using activity-based proteomics.
Eric S Okerberg +10 more
doaj +1 more source
Advanced Science, EarlyView.Large‐scale UK Biobank analyses identify clinical and proteomic signatures for early prediction of valvular heart disease and its subtypes. Proteins add predictive value for VHD, AVS, and MVR, with outcome‐specific compact panels showing translational potential. Multi‐layer evidence highlights matrix remodeling, protease regulation, immune inflammation,
Zhihao Jiang +10 more
wiley +1 more source
Scientific Reports, 2022 A large set of nucleobases and amino acids is found in meteorites, implying that several chemical reservoirs are present in the solar system. The “geochemical continuity” hypothesis explores how protometabolic paths developed from so-called “bricks” in ...
Louis M. P. Ter-Ovanessian +2 more
doaj +1 more source
, 2016 Among many hurdles in synthesizing proteoglycan glycopeptides, one challenge is the incorporation of aspartic acid in the peptide backbone and acid sensitive O-sulfated glycan chains. To overcome this, a new strategy was developed utilizing homoserine as
Xuefei Huang (1261959) +4 more
core +1 more source
, 2020 Sem informaçãoA mother crystal formed from a transient molecular structure of (D+L) aspartic acid in solution is reported. Hexagonal structures with a lattice constant of 1.04 nm were crystallized from a solution in which three aspartic acid species ...
Teschke, O., Soares, D. M.
core +1 more source