Results 41 to 50 of about 124,711 (254)

Encoded Cell‐Material Interactions to Reroute Cytokine Signaling for Regenerative Medicine

open access: yesAdvanced Healthcare Materials, EarlyView.
We present native MATRIX (Material Activated To Regulate Inducible gene eXpression), a co‐engineered material‐cell platform. Surfaces functionalized with antibodies for endogenous soluble ligands (e.g., IL‐1β or IL‐6) capture and immobilize ligands for presentation to a cognate, engineered synthetic Notch receptor, releasing a transcription factor (TF)
Zachary M. Eidman   +7 more
wiley   +1 more source

Aspartate kinase and the synthesis of aspartate-derived amino acids in wheat

open access: yesPlanta, 1978
Aspartate kinase (EC 2.7.2.4.) has been purified from 7 day etiolated wheat (Triticum aestivum L. var. Maris Freeman) seedlings and from embryos imbibed for 8 h. The enzyme was 50% inhibited by 0.25 mM lysine. In this study wheat aspartate kinase was not inhibited by threonine alone or cooperatively with lysine; these results contrast with those ...
Bright, S. W. J.   +2 more
openaire   +2 more sources

Positively Charged Polymer‐Brush MOFs for Large‐Area, Pressure‐Resistant Gas Separation Membranes

open access: yesAdvanced Materials, EarlyView.
A universal POPA strategy enables positively charged polymer‐brush MOFs with self‐adaptive interfacial interlocking to resist aggregation under fast processing. This design ensures seamless dispersion within large‐area selective layers, achieving 1 m‐wide roll‐to‐roll fabrication of pressure‐resistant MMCMs with tunable CO2 separation performance ...
Yi Yang   +11 more
wiley   +1 more source

Aberrant amino acid metabolism promotes neurovascular reactivity in rosacea

open access: yesJCI Insight, 2022
Rosacea is a chronic skin disorder characterized by abnormal neurovascular and inflammatory conditions on the central face. Despite increasing evidence suggesting that rosacea is associated with metabolic disorders, the role of metabolism in rosacea ...
Tangxiele Liu   +10 more
doaj   +1 more source

A Chemical Framework for Engineering Extracellular Vesicles’ Biointerface to Advance Precision Therapeutics

open access: yesAdvanced Materials, EarlyView.
Extracellular vesicles (EVs) are cell‐derived nanoparticles that mediate intercellular communication through their dynamic biointerfaces. Owing to their intrinsic biological functions, EVs have emerged as promising platforms for biomedical applications.
Leila Pourtalebi Jahromi   +3 more
wiley   +1 more source

Regulation of Calcium Absorption in Caco-2 Cells by Aspartic Acid, Glutamic Acid and Their Glycine Dipeptides

open access: yesShipin gongye ke-ji
In order to investigate the mechanism of aspartic acid, glutamic acid and their glycine dipeptides on calcium ion uptake, the isothermal titration calorimetry technique, electrochemistry, and Caco-2 cell model combined with quantum mechanical calculation
Jiachen LIU   +3 more
doaj   +1 more source

NH2-terminal amino acids of the serum lipoproteins of normal and hypercholesterolemic rabbits*

open access: yesJournal of Lipid Research, 1960
Aspartic acid is the major and glutamic acid and serine are minor NH2-terminal amino acids of the lipoproteins of rabbit serum. No NH2-terminal amino acids other than these are found after prolonged cholesterol feeding.
B. Shore, V. Shore
doaj   +1 more source

Multifunctional Wound Dressings: Melt Electrowritten Scaffolds Combined With Phytotherapeutic Composite Hydrogels

open access: yesAdvanced Materials Interfaces, EarlyView.
ABSTRACT The increasing prevalence of impaired wounds, caused mainly by diabetes or aging, alongside the growing number of bacterial infections, indicates the need for alternative tissue engineering solutions. In this study, we developed novel melt electrowritten (MEW) polycaprolactone (PCL) scaffolds incorporated with an alginate (Alg)–gelatin (Gel ...
Andrada‐Ioana Damian‐Buda   +2 more
wiley   +1 more source

Effect of chemical compounds on amino acid content of some Fusarium species and its significance to fungal chemotaxonomy

open access: yesJournal of Saudi Chemical Society, 2011
The cellular amino acid profiles of nine species of Fusarium; namely, Fusarium anthophilum, Fusarium avenaceum, Fusarium cerealis, Fusarium graminearum, Fusarium graminum, Fusarium oxysporum f. sp.
M.E. Zain   +2 more
doaj   +1 more source

Identification of a Tumor Specific, Active-Site Mutation in Casein Kinase 1α by Chemical Proteomics. [PDF]

open access: yesPLoS ONE, 2016
We describe the identification of a novel, tumor-specific missense mutation in the active site of casein kinase 1α (CSNK1A1) using activity-based proteomics.
Eric S Okerberg   +10 more
doaj   +1 more source

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