Results 1 to 10 of about 5,031 (95)

The role of lysosomal peptidases in glioma immune escape: underlying mechanisms and therapeutic strategies

Frontiers in Immunology, 2023
Glioblastoma is the most common primary malignant tumor of the central nervous system, which has the characteristics of strong invasion, frequent recurrence, and rapid progression.
Hao Liu, Hao Liu, Jie Peng, Jie Peng, Linzhen Huang, Dong Ruan, Yuguang Li, Fan Yuan, Zewei Tu, Zewei Tu, Zewei Tu, Zewei Tu, Kai Huang, Kai Huang, Kai Huang, Kai Huang, Xingen Zhu, Xingen Zhu, Xingen Zhu, Xingen Zhu   +19 more
doaj   +1 more source

Histidine and Aspartic Acid Residues Important for Immunoglobulin G Endopeptidase Activity of the Group AStreptococcusOpsonophagocytosis-Inhibiting Mac Protein [PDF]

Infection and Immunity, 2003
ABSTRACTThe secreted Mac protein made by serotype M1 group AStreptococcus(GAS) (designated Mac5005) inhibits opsonophagocytosis and killing of GAS by human polymorphonuclear neutrophils. This protein also has cysteine endopeptidase activity against human immunoglobulin G (IgG).
Benfang, Lei, Mengyao, Liu, Elishia G, Meyers, Heather M, Manning, Michael J, Nagiec, James M, Musser   +5 more
openaire   +2 more sources

Phosphorylated acidic serine–aspartate-rich MEPE-associated motif peptide from matrix extracellular phosphoglycoprotein inhibits phosphate regulating gene with homologies to endopeptidases on the X-chromosome enzyme activity [PDF]

Journal of Endocrinology, 2007
Inactivating PHEX (phosphate regulating gene with homologies to endopeptidases on the X chromosome) mutations cause X-linked hypophosphatemia in humans and mice (Hyp) through overproduction of fibroblast growth factor 23 (FGF23) a phosphaturic factor, by osteocytes.
Shiguang, Liu, Peter S N, Rowe, Luke, Vierthaler, Jianping, Zhou, L Darryl, Quarles   +4 more
openaire   +2 more sources

Cathepsin E (EC 3.4.23.34) — a review

Folia Histochemica et Cytobiologica, 2012
Cathepsin E belongs to the third class of enzymes — hydrolases, a subclass of peptide bond hydrolases and a sub-subclass of endopeptidases with aspartic catalytic sites. Cathepsin E is an endopeptidase with substrate specificity similar to that
Anna Worowska, Marek Gacko, Michał Chlabicz, Radosław Łapiński   +3 more
doaj   +1 more source

Purification and characterization of an aspartic protease from the Rhizopus oryzae protease extract, Peptidase R

Electronic Journal of Biotechnology, 2014
Background: Aspartic proteases are a subfamily of endopeptidases that are useful in a variety of applications, especially in the food processing industry.
Nai-Wan Hsiao, Yeh Chen, Yi-Chia Kuan, Yen-Chung Lee, Shuo-Kang Lee, Hsin-Hua Chan, Chao-Hung Kao   +6 more
doaj   +1 more source

The Role of Microbial Aspartic Protease Enzyme in Food and Beverage Industries

Journal of Food Quality, 2018
Proteases represent one of the three largest groups of industrial enzymes and account for about 60% of the total global enzymes sale. According to the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology, proteases are ...
Jermen Mamo, Fassil Assefa
doaj   +1 more source

Conformational Dynamics of Plasmepsin X during Inhibitor Binding. [PDF]

J Phys Chem B
Karubiu W, Kullmann R, Krummhaar M, Roth C, Weikl TR.   +4 more
europepmc   +1 more source

Microbial proteases and endothelial barrier disruption in sepsis: A neglected nexus. [PDF]

Virulence
Rao SS, Shenoy M S, Gutti RK, Prabhu V, Joshi M, Nayak UY, Bharath Prasad AS.   +6 more
europepmc   +1 more source

Unlocking Bioactive, Peptide-Rich Extracts from Tomato Seeds Using Enzymatic-Assisted Extraction. [PDF]

Foods
Benati G, Ferri M, Barbieri T, Tassoni A.   +3 more
europepmc   +1 more source

Phytochemical profiling of Vitex negundo seeds via UHPLC-QTOF-MS/MS analyses with antimicrobial evaluation and in silico targeting of DNA Gyrase B and Secreted Aspartic Proteinase 2 (SAP2). [PDF]

PLoS One
Mustafa J, Ashraf T, Ali B, Kousar S, Mahmood A, Ullah S, Imran M, Ali B, Rahim U, Yunis M.   +9 more
europepmc   +1 more source