Results 21 to 30 of about 5,031 (95)
Proteolytic remodelling of the extracellular matrix by pericytes
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard +4 more
wiley +1 more source
Racemisation of Amino Acids: From Synthetic Challenge to Biological Significance
Racemisation, once considered an undesirable synthetic side reaction, also occurs naturally in amino acids and influences biological processes. Evidence links stereochemical conversion to ageing, protein turnover, and cellular development. This review examines mechanisms, control strategies in synthesis, applications and implications in physiology ...
Othman Al Musaimi
wiley +1 more source
Despite their evolutionary relatedness to malaria parasites that infect humans, wildlife Plasmodium—particularly those that infect birds and lizards—are understudied, leaving their vast genetic diversity to be explored. By assembling parasite transcriptomes from Plasmodium‐infected lizard blood, we provide the first evidence that lizard‐infective ...
Sarah J. Pangburn +4 more
wiley +1 more source
ProteAX‐assisted hydrolysis of cricket (Acheta domesticus) protein enhanced its techno‐functional and sensory properties. Optimal hydrolysis at a 1.5% enzyme concentration for 5 h produced a hydrolysate with a 67.71% degree of hydrolysis, 69.51% protein content, high solubility, improved water and oil absorption capacities, low bitterness, and a strong
Fetriyuna Fetriyuna +4 more
wiley +1 more source
Integrative Genomics Identifies Candidate Genes Underlying Trypanotolerance in Hybrid African Cattle
ABSTRACT Integrative genomics combines data from different omics sources to link genotypes and phenotypes with the aim of unravelling biological networks and pathways that undergird complex traits, particularly with respect to disease. In this respect, integrative genomics, leveraging population and functional genomic data, can be employed to ...
Gillian P. McHugo +10 more
wiley +1 more source
How to Reduce Wheat Allergens and FODMAPs in Foods: A Critical Review of Patents
ABSTRACT Background and Objectives Supported by scientific evidence, this critical review of the patent literature examined methods to reduce wheat allergens and FODMAPs in foods, which may trigger digestive disorders and other health problems. The following topics were covered: proteolytic enzymes, proteolytic bacteria and yeasts, separation, plant ...
Pierre Gélinas, Jérémie Théolier
wiley +1 more source
Abstract Legumain is a lysosomal cysteine protease that plays a central role in antigen processing for MHC class II presentation. Beyond its canonical proteolytic activity, legumain can also function as a peptide ligase or transpeptidase. This non‐canonical activity becomes particularly relevant under pathophysiological conditions such as cancer and ...
Rupert Klaushofer +3 more
wiley +1 more source
Processing and release of endogenous immunogenic peptide signals
SUMMARY In both animals and plants, small secreted peptides known as cytokines and phytocytokines mediate local and systemic communication during immune and stress responses. These signaling molecules are typically synthesized as inactive precursors that require proteolytic processing to become active.
Maurice Koenig +3 more
wiley +1 more source
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley +1 more source
Specific role of two NlpC/P60 endopeptidases in cell division and membrane vesicle formation in <i>Deinococcus radiodurans</i>. [PDF]
Kamara T +6 more
europepmc +1 more source

