Results 21 to 30 of about 51,805 (174)
Partial Characterization of Two Cathepsin D Family Aspartic Peptidases of Clonorchis sinensis
Cathepsin D (CatD, EC 3.4.23.5) is a member belonging to the subfamily of aspartic endopeptidases, which are classified into the MEROPS clan AA, family A1. Helminth parasites express a large set of different peptidases that play pivotal roles in parasite
Jung-Mi Kang +6 more
semanticscholar +1 more source
Exploring the mialome of ticks: An annotated catalogue of midgut transcripts from the hard tick, Dermacentor variabilis (Acari: Ixodidae) [PDF]
Background Ticks are obligate blood feeders. The midgut is the first major region of the body where blood and microbes ingested with the blood meal come in contact with the tick's internal tissues.
Daniel E Sonenshine +2 more
core +4 more sources
Recombinant expression and functional analysis of proteases from Streptococcus pneumoniae, Bacillus anthracis, and Yersinia pestis [PDF]
Background Uncharacterized proteases naturally expressed by bacterial pathogens represents important topic in infectious disease research, because these enzymes may have critical roles in pathogenicity and cell physiology.
Keehwan Kwon +7 more
core +1 more source
Yeast Ortholog of Peptidase Family M49: the Role of Invariant Glu(461) and Tyr(327) [PDF]
Metallopeptidase family M49 is characterized by five conserved sequence regions and the unique motif HEXXGH with two histidines - ligands of the active-site zinc ion. The crystal structure of the yeast ortholog represents a prototype for the whole family.
Abramić, Marija +2 more
core +2 more sources
Proteases of haematophagous arthropod vectors are involved in blood-feeding, yolk formation and immunity : a review [PDF]
Ticks, triatomines, mosquitoes and sand flies comprise a large number of haematophagous arthropods considered vectors of human infectious diseases. While consuming blood to obtain the nutrients necessary to carry on life functions, these insects can ...
A Ali +173 more
core +2 more sources
Aspartic Acid in Health and Disease
Aspartic acid exists in L- and D-isoforms (L-Asp and D-Asp). Most L-Asp is synthesized by mitochondrial aspartate aminotransferase from oxaloacetate and glutamate acquired by glutamine deamidation, particularly in the liver and tumor cells, and ...
M. Holeček
semanticscholar +1 more source
THE CONCISE GUIDE TO PHARMACOLOGY 2017/18:Enzymes [PDF]
The Concise Guide to PHARMACOLOGY 2017/18 provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to an open access knowledgebase of drug targets and ...
, +11 more
core +15 more sources
Salinity is the primary environmental stress that adversely affects plants’ growth and productivity in many areas of the world. Published research validated the role of aspartic acid in improving plant tolerance against salinity stress. Therefore, in the
M. S. Sadak +8 more
semanticscholar +1 more source
Agriculture is facing a great number of different pressures due to the increase in population and the greater amount of food it demands, the environmental impact due to the excessive use of conventional fertilizers, and climate change, which subjects the
M. Alfosea-Simón +7 more
semanticscholar +1 more source
A biotechnology perspective of fungal proteases [PDF]
Proteases hydrolyze the peptide bonds of proteins into peptides and amino acids, being found in all living organisms, and are essential for cell growth and differentiation.
Almeida, Renata Paula Coppini de +9 more
core +1 more source

