Results 21 to 30 of about 182,862 (296)

Screening of proteases produced by Aspergillus micromycetes active against proteins of the hemostasis system [PDF]

Current Medical Mycology, 2023
Background and Purpose: The primary cause of death is cardiovascular disease, hence accurate diagnosis and treatment are urgently required. For these intents, proteases are regarded as perspective agents.
Daria Surkova, Viktoria Lavrenova, Sergey Klyagin, Anna Shestakova, Alexander Osmolovskiy   +4 more
doaj   +1 more source

The Glycosylphosphatidylinositol-Anchored DFG Family Is Essential for the Insertion of Galactomannan into the β-(1,3)-Glucan–Chitin Core of the Cell Wall of Aspergillus fumigatus

mSphere, 2019
The fungal cell wall is a complex and dynamic entity essential for the development of fungi. It is composed mainly of polysaccharides that are synthetized by protein complexes.
Laetitia Muszkieta, Thierry Fontaine, Rémi Beau, Isabelle Mouyna, Marian Samuel Vogt, Jonathan Trow, Brendan P. Cormack, Lars-Oliver Essen, Gregory Jouvion, Jean-Paul Latgé   +9 more
doaj   +1 more source

Host Soluble Mediators: Defying the Immunological Inertness of Aspergillus fumigatus Conidia

Journal of Fungi, 2017
Aspergillus fumigatus produce airborne spores (conidia), which are inhaled in abundant quantity. In an immunocompromised population, the host immune system fails to clear the inhaled conidia, which then germinate and invade, leading to pulmonary ...
Sarah Sze Wah Wong, Vishukumar Aimanianda   +1 more
doaj   +1 more source

Vaccine-Induced Protection in Two Murine Models of Invasive Pulmonary Aspergillosis

Frontiers in Immunology, 2021
Life-threatening, invasive fungal infections (IFIs) cause over 1.5 million deaths worldwide and are a major public health concern with high mortality rates even with medical treatment.
Emily Rayens, Emily Rayens, Whitney Rabacal, S. Earl Kang, Brandi N. Celia, Michelle Momany, Karen A. Norris, Karen A. Norris   +7 more
doaj   +1 more source

Disseminated invasive aspergillosis caused by Aspergillus felis in a cat

Journal of Veterinary Internal Medicine, 2021
A 2‐year‐old male desexed Ragdoll cat with a 1‐year history of sneezing and nasal discharge presented with a large subcutaneous cervical mass, identified as the right medial retropharyngeal lymph node on computed tomography (CT).
Catherine A. Cormack, Shannon L. Donahoe, Jessica J. Talbot, Julia A. Beatty, Vanessa R. Barrs   +4 more
doaj   +1 more source

Definition of the Anti-inflammatory Oligosaccharides Derived From the Galactosaminogalactan (GAG) From Aspergillus fumigatus

Frontiers in Cellular and Infection Microbiology, 2019
Galactosaminogalactan (GAG) is an insoluble aminosugar polymer produced by Aspergillus fumigatus and has anti-inflammatory properties. Here, the minimum glycosidic sequences required for the induction of IL-1Ra by peripheral blood mononuclear cells ...
Markus Gressler, Christoph Heddergott, Inés C. N'Go, Giorgia Renga, Vasilis Oikonomou, Silvia Moretti, Bernadette Coddeville, Joana Gaifem, Joana Gaifem, Ricardo Silvestre, Ricardo Silvestre, Luigina Romani, Jean-Paul Latgé, Thierry Fontaine   +13 more
doaj   +1 more source

Metagenomic next-generation sequencing for the diagnosis of pulmonary aspergillosis in non-neutropenic patients: a retrospective study

Frontiers in Cellular and Infection Microbiology, 2022
This study aimed to obtain further in-depth information on the value of metagenomic next-generation sequencing (mNGS) for diagnosing pulmonary aspergillosis in non-neutropenic patients.
Shujun Bao, Huihui Song, Yang Chen, Caiming Zhong, Hao Tang   +4 more
doaj   +1 more source

Role of Hydrophobins in Aspergillus fumigatus

Journal of Fungi, 2017
Resistance of Aspergillus fumigatus conidia to desiccation and their capacity to reach the alveoli are partly due to the presence of a hydrophobic layer composed of a protein from the hydrophobin family, called RodA, which covers the conidial surface. In
Isabel Valsecchi, Vincent Dupres, Emmanuel Stephen-Victor, J. Iñaki Guijarro, John Gibbons, Rémi Beau, Jagadeesh Bayry, Jean-Yves Coppee, Frank Lafont, Jean-Paul Latgé, Anne Beauvais   +10 more
doaj   +1 more source

Glycosylphosphatidylinositol Anchors from Galactomannan and GPI-Anchored Protein Are Synthesized by Distinct Pathways in Aspergillus fumigatus

Journal of Fungi, 2018
Glycosylphosphatidylinositols (GPIs) are lipid anchors allowing the exposure of proteins at the outer layer of the plasma membrane. In fungi, a number of GPI-anchored proteins (GPI-APs) are involved in the remodeling of the cell wall polymers.
Jizhou Li, Isabelle Mouyna, Christine Henry, Frédérique Moyrand, Christian Malosse, Julia Chamot-Rooke, Guilhem Janbon, Jean-Paul Latgé, Thierry Fontaine   +8 more
doaj   +1 more source

Live imaging and quantitative analysis of Aspergillus fumigatus growth and morphology during inter-microbial interaction with Pseudomonas aeruginosa

Virulence, 2020
Pseudomonas aeruginosa (PA) and Aspergillus fumigatus (AF) chronically colonize the airways of patients with cystic fibrosis or chronic immunosuppression and mutually affect each other’s pathogenesis.
Sebastian Wurster, Gabriele Sass, Nathaniel D. Albert, Hasan Nazik, Eric Déziel, David A. Stevens, Dimitrios P. Kontoyiannis   +6 more
doaj   +1 more source