Results 41 to 50 of about 232,874 (323)

Genome sequencing of evolved aspergilli populations reveals robust genomes, transversions in A. flavus, and sexual aberrancy in non-homologous end-joining mutants [PDF]

, 2019
BACKGROUND: Aspergillus spp. comprises a very diverse group of lower eukaryotes with a high relevance for industrial applications and clinical implications. These multinucleate species are often cultured for many generations in the laboratory, which can
Amirebrahimi, Mojgan, Bok, Jin Woo, Cea Sánchez, Sara, Cánovas López, David, Gutiérrez Pozo, Gabriel, Marcos Rodríguez, Ana Teresa, Na, Hyunsoo, Sasse, Christoph, Álvarez Escribano, Isidro   +8 more
core   +1 more source

Mechanisms of Triazole Resistance in Aspergillus fumigatus.

Environmental Microbiology, 2020
The ubiquitous fungal pathogen Aspergillus fumigatus is the primary cause of opportunistic mold infections in humans. Aspergilli disseminate via asexual conidia passively traveling through air currents to germinate within a broad range of environs ...
Ashley V. Nywening, J. Rybak, P. Rogers, J. Fortwendel   +3 more
semanticscholar   +1 more source

Species-Specific Immunological Reactivities Depend on the Cell-Wall Organization of the Two Aspergillus, Aspergillus fumigatus and A. flavus

Frontiers in Cellular and Infection Microbiology, 2021
Although belong to the same genus, Aspergillus fumigatus is primarily involved in invasive pulmonary infection, whereas Aspergillus flavus is a common cause of superficial infection.
Sarah Sze Wah Wong, Sarah Sze Wah Wong, Lakshmi Prabha Venugopalan, Audrey Beaussart, Anupama Karnam, Mohammed Razeeth Shait Mohammed, Jeya Maheshwari Jayapal, Stéphane Bretagne, Jagadeesh Bayry, Lalitha Prajna, Dharmalingam Kuppamuthu, Jean-Paul Latgé, Vishukumar Aimanianda, Vishukumar Aimanianda   +13 more
doaj   +1 more source

Structural and biochemical characterization of the exopolysaccharide deacetylase Agd3 required for Aspergillus fumigatus biofilm formation

Nature Communications, 2020
The exopolysaccharide galactosaminogalactan (GAG) is an important virulence factor of the fungal pathogen Aspergillus fumigatus. Deletion of a gene encoding a putative deacetylase, Agd3, leads to defects in GAG deacetylation, biofilm formation, and ...
N. C. Bamford, N. C. Bamford, François Le Mauff, Jaime C. Van Loon, Hanna Ostapska, Brendan D. Snarr, Yongzhen Zhang, E. Kitova, John S. Klassen, J. Codée, D. Sheppard, P. Howell   +11 more
semanticscholar   +1 more source

Allergic bronchopulmonary aspergillosis: diagnostic and treatment challenges [PDF]

, 2016
Allergic bronchopulmonary aspergillosis (ABPA) is a pulmonary disorder, occurring mostly in asthmatic and cystic fibrosis patients, caused by an abnormal T-helper 2 lymphocyte response of the host to Aspergillus fumigatus antigens.
CINICOLA, BIANCA LAURA, DUSE, MARZIA, Laitano, Rossella, LEONARDI, LUCIA   +3 more
core   +1 more source

rodletless mutants of Aspergillus fumigatus [PDF]

Infection and Immunity, 1994
Conidia of Aspergillus fumigatus adhere in vitro to host proteins and cells via the outer cell wall layer. The rodA gene of A. fumigatus was cloned by homology with the rodA gene of Aspergillus nidulans, which is involved in the structure of the rodlets characteristic of the surface layer. The A.
N, Thau, M, Monod, B, Crestani, C, Rolland, G, Tronchin, J P, Latgé, S, Paris   +6 more
openaire   +2 more sources

Targeting the Membrane‐Embedded Rhomboid Protease GlpG: A Multimodal Strategy for Inhibitor Discovery and Mechanistic Insight

Angewandte Chemie, EarlyView.
Created in BioRender. Bohg, C. (2026) https://BioRender.Com/ vi9hi4f. Rhomboid proteases are a mechanistically unique and evolutionarily conserved protein family. Despite their pharmacological relevance, the development of selective inhibitors has lagged behind that of soluble proteases.
Claudia Bohg, Yurii Dubanych, Spyridon Kosteletos, Taoran Xiao, Martin Neuenschwander, Tillmann Utesch, Michael Lisurek, Carl Öster, Andreas Oder, Carola Seyffarth, Kathrin Bach, Denise‐Liù Gracias Leone, František Filandr, Marc Wegert, Sascha Lange, Henry Sawczyc, Jens Peter von Kries, Christian P. R. Hackenberger, Edgar Specker, Han Sun, Kvido Stříšovský, Adam Lange   +21 more
wiley   +2 more sources

Metagenomic Next-Generation Sequencing Assists in the Diagnosis of Mediastinal Aspergillus fumigatus Abscess in an Immunocompetent Patient: A Case Report and Literature Review

Infection and Drug Resistance, 2023
Wusheng Deng,1,* Yun Jiang,2,* Jiaoxia Qin,1,* Gang Chen,3,* Yongjie Lv,1 Yanmei Lei,1 Jing Luo,1 Kangkang Hong,1 Bing Huang,1 Luhai Qin,4 Xiujia Tang,1 Liumei Ye,1 Yuhai Dang,1 Chao Wang,1 Feiyang Long,1 Ke Wang,1 Jinliang Kong1 ...
Deng W, Jiang Y, Qin J, Chen G, Lv Y, Lei Y, Luo J, Hong K, Huang B, Qin L, Tang X, Ye L, Dang Y, Wang C, Long F, Wang K, Kong J   +16 more
doaj  

Additivity interactions between fluconazole and citrus essential oils to Aspergillus fumigatus

Journal of Pre-Clinical and Clinical Research, 2021
Introduction Aspergillus fumigatus is the most common pathogen causing allergic bronchopulmonary mycosis. The pathogenic capacity of Aspergillus fumigatus is related to its thermal tolerance and the small size of the ...
Paula Wróblewska-Łuczka, Jarogniew Łuszczki   +1 more
doaj   +1 more source

Aspergillus fumigatus preexposure worsens pathology and improves control of Mycobacterium abscessus pulmonary infection in mice [PDF]

, 2018
Cystic fibrosis (CF) is an autosomal recessive disease caused by mutations in the CF transmembrane conductance regulator (CFTR) gene. Mutations in this chloride channel lead to mucus accumulation, subsequent recurrent pulmonary infections, and ...
Elsegeiny, Waleed, Gopal, Radha, Khader, Shabaana A, Kolls, Jay, McAleer, Jeremy P, Mehta, Shail, Monin, Leticia, Oury, Tim D   +7 more
core   +2 more sources