Results 51 to 60 of about 186,086 (280)

Nonrandom Distribution of Azole Resistance across the Global Population of Aspergillus fumigatus

mBio, 2019
Azole drug resistance in the human-pathogenic fungus Aspergillus fumigatus continues to emerge, potentially leading to untreatable aspergillosis in immunosuppressed hosts.
Thomas R. Sewell, Jianing Zhu, J. Rhodes, F. Hagen, J. Meis, M. Fisher, T. Jombart   +6 more
semanticscholar   +1 more source

Mutations in hmg1, Challenging the Paradigm of Clinical Triazole Resistance in Aspergillus fumigatus

mBio, 2019
Aspergillus fumigatus is the predominant pathogen of invasive aspergillosis, a disease state credited with over 200,000 life-threatening infections annually.
J. Rybak, Wenbo Ge, N. Wiederhold, J. Parker, S. Kelly, P. Rogers, J. Fortwendel   +6 more
semanticscholar   +1 more source

Degradation of melanin by Aspergillus fumigatus [PDF]

Applied and Environmental Microbiology, 1980
A strain of Aspergillus fumigatus from composted coffee and garden wastes utilized natural deproteinized insect, banana, hair, octopus, and synthetic tyrosine and dopa melanins as sole sources of carbon. With a sucrose supplement, degradation was essentially complete after 50 days in Czapek medium pH 6.5 at 30 degrees C. The catabolic rate differed for
H Lipke, J P Luther
openaire   +2 more sources

Structural, Mechanical, and Genetic Insights into Heat‐Pressed Fomes Fomentarius Mycelium from Solid‐State and Liquid Cultivations

Advanced Sustainable Systems, EarlyView.
Fungal mycelium‐based materials are an upcoming class of sustainable materials. Heat ‐pressing is a promising post‐processing technique to produce fungal mycelium‐based particle boards or leather substitutes. However, little is known about the mechanism involved.
Huaiyou Chen, Sophie Klemm, Ernesto Scoppola, Bertram Schmidt, Yunpeng Wu, Claudia Fleck, Aleksander Gurlo, Vera Meyer, Carsten Freidank‐Pohl, Ulla Simon   +9 more
wiley   +1 more source

Profile and functional analysis of small RNAs derived from Aspergillus fumigatus infected with double-stranded RNA mycoviruses

BMC Genomics, 2017
Background Mycoviruses are viruses that naturally infect and replicate in fungi. Aspergillus fumigatus, an opportunistic pathogen causing fungal lung diseases in humans and animals, was recently shown to harbour several different types of mycoviruses.
Selin Özkan, Irina Mohorianu, Ping Xu, Tamas Dalmay, Robert H. A. Coutts   +4 more
doaj   +1 more source

In-situ detection of Aspergillus fumigatus [PDF]

Journal of Medical Microbiology, 2000
An in-situ hybridisation (ISH) technique to detect Aspergillus fumigatus in infected tissues was developed in which 568-bp, 333-bp and 154-bp PCR products of the alkaline proteinase gene were employed. Dot-blot hybridisation with the 568-bp probe on a membrane containing genomic DNA from several different fungi including A. flavus, A.
Somay Yamagata Murayama, Hideyo Yamaguchi, Ryo Hanazawa   +2 more
openaire   +2 more sources

Homeostasis of Gut Microbiota Protects against Susceptibility to Fungal Pneumonia

Advanced Science, EarlyView.
Fungal pneumonia induces inflammation, shown by heightened IL‐6, IL‐1β, TNF‐α levels and a growth in Staphylococcus in the alveolar flora. The gut microbiota, acting through the gut‐lung axis via blood, impacts fungal pneumonia susceptibility by altering lung metabolism and inflammatory responses.
Jian Ji, Yongli Ye, Jiadi Sun, Lina Sheng, Jinyou Li, Jin Yang, Bing Wu, Yuting Wang, Xingxing Gao, Liang Luo, Jianfeng Ping, Yinzhi Zhang, Xiulan Sun   +12 more
wiley   +1 more source

Correlation between serum galactomannano level and Aspergillus fumigatus specific antibody in patients with allergic bronchopulmonary aspergillus recurrence [PDF]

Jichu yixue yu linchuang
Objective To explore the relationship between serum galactomannano (GM) level and specific antibody level of Aspergillus fumigatus in patients with allergic bronchopulmonary aspergillus (ABPA) recurrence.
WANG Wentao, TAN Wei
doaj   +1 more source

Molecular Chain Elongation Mechanism for n‐Caproate Biosynthesis by Megasphaera Hexanoica

Advanced Science, EarlyView.
The medium‐chain carboxylate‐producing microbe Megasphaera hexanoica is analyzed through genomics, transcriptomics, and metabolic engineering. The n‐caproate biosynthetic pathway is reconstructed in Escherichia coli, highlighting MhTHL as a key β‐ketothiolase. Structural analysis and mutagenesis reveal that MhTHL has a distinct substrate‐binding pocket,
Byoung Seung Jeon, Eun‐Jung Kim, Hogyun Seo, Hyunjin Kim, Seungjin Shin, Caroline Schlaiß, Largus T. Angenent, Kyung‐Jin Kim, Byoung‐In Sang   +8 more
wiley   +1 more source

Characterization of Aspergillus fumigatus Extracellular Vesicles and Their Effects on Macrophages and Neutrophils Functions

Frontiers in Microbiology, 2019
Extracellular vesicles (EVs) has been considered an alternative process for intercellular communication. EVs release by filamentous fungi and the role of vesicular secretion during fungus-host cells interaction remain unknown.
Jéssica A M Souza, Ludmila M. Baltazar, V. M. Carregal, Ludmila Gouveia-Eufrásio, A. G. de Oliveira, W. Dias, Marina Campos Rocha, Kildare Rocha de Miranda, I. Malavazi, D. A. Santos, F. Frézard, D. G. D. de Souza, M. Teixeira, F. Soriani   +13 more
semanticscholar   +1 more source