Results 31 to 40 of about 312,145 (352)

Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus

New England Journal of Medicine, 2018
BACKGROUND Diabetes mellitus is associated with an increased risk of cardiovascular events. Aspirin use reduces the risk of occlusive vascular events but increases the risk of bleeding; the balance of benefits and hazards for the prevention of first ...
L. Bowman, M. Mafham, K. Wallendszus, W. Stevens, G. Buck, J. Barton, K. Murphy, Theingi Aung, R. Haynes, J. Cox, A. Murawska, A. Young, M. Lay, Fang Chen, E. Sammons, Emma Waters, A. Adler, J. Bodansky, A. Farmer, R. Mcpherson, A. Neil, D. Simpson, R. Peto, C. Baigent, R. Collins, S. Parish, J. Armitage   +26 more
semanticscholar   +1 more source

Aspirin with or without Clopidogrel after Transcatheter Aortic-Valve Implantation.

New England Journal of Medicine, 2020
BACKGROUND The effect of single as compared with dual antiplatelet treatment on bleeding and thromboembolic events after transcatheter aortic-valve implantation (TAVI) in patients who do not have an indication for long-term anticoagulation has not been ...
J. Brouwer, V. Nijenhuis, R. Delewi, R. Hermanides, W. Holvoet, C. Dubois, P. Frambach, B. de Bruyne, G. V. van Houwelingen, J. van der Heyden, P. Toušek, F. van der Kley, I. Buysschaert, C. Schotborgh, B. Ferdinande, P. van der Harst, J. Roosen, J. Peper, Frederick W F Thielen, L. Veenstra, D. R. Chan Pin Yin, M. Swaans, B. Rensing, A. W. van ’t Hof, L. Timmers, J. Kelder, P. Stella, J. Baan, J. T. ten Berg   +28 more
semanticscholar   +1 more source

Identifying and reducing inappropriate aspirin use in primary care

BMJ Open Quality, 2023
Objective Recent studies have called into question the safety of aspirin use for the primary prevention of atherosclerotic cardiovascular disease, particularly in older adults.
Li Li, Christa Brooker, Rebekah Compton, Terri Babineau, Cornelius Afetorli Normeshie, Sarah Rachel Blackstone   +5 more
doaj   +1 more source

Clopidogrel and Aspirin in Acute Ischemic Stroke and High‐Risk TIA

New England Journal of Medicine, 2018
BACKGROUND Combination antiplatelet therapy with clopidogrel and aspirin may reduce the rate of recurrent stroke during the first 3 months after a minor ischemic stroke or transient ischemic attack (TIA).
S. Johnston, D. Easton, M. Farrant, W. Barsan, R. Conwit, C. Johnston, J. Easton, J. Elm, A. Kim, Anne S. Lindbald, Y. Palesch   +10 more
semanticscholar   +1 more source

Association of Aspirin with Hepatocellular Carcinoma and Liver-Related Mortality.

New England Journal of Medicine, 2020
BACKGROUND More information is needed about the long-term effects of low-dose aspirin (≤160 mg) on incident hepatocellular carcinoma, liver-related mortality, and gastrointestinal bleeding in persons with chronic hepatitis B or hepatitis C virus ...
Tracey G. Simon, Ann-Sofi Duberg, S. Aleman, R. Chung, A. Chan, J. Ludvigsson   +5 more
semanticscholar   +1 more source

Aspirin resistance in patients with acute coronary syndrome. Part 2

Кардиоваскулярная терапия и профилактика, 2011
Aim. In patients with acute coronary syndrome (ACS), to investigate the prevalence of aspirin resistance, its clinical features, prognostic effects, and potential correction. Material and methods.
N. S. Frolova, R. M. Shakhnovich, E. M. Kaznacheeva, O. V. Sirotkina, A. B. Dobrovolskyi   +4 more
doaj   +1 more source

Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly

New England Journal of Medicine, 2018
BACKGROUND Aspirin is a well‐established therapy for the secondary prevention of cardiovascular events. However, its role in the primary prevention of cardiovascular disease is unclear, especially in older persons, who have an increased risk.
J. McNeil, R. Wolfe, R. Woods, A. Tonkin, G. Donnan, Mark R. Nelson, C. Reid, J. Lockery, B. Kirpach, E. Storey, R. Shah, J. Williamson, K. Margolis, M. Ernst, W. Abhayaratna, N. Stocks, S. Fitzgerald, S. Orchard, R. Trevaks, L. Beilin, C. Johnston, J. Ryan, B. Radziszewska, M. Jelinek, M. Malik, C. Eaton, D. Brauer, G. Cloud, E. Wood, S. Mahady, S. Satterfield, R. Grimm, A. Murray   +32 more
semanticscholar   +1 more source

Aspirin Use Is Associated With Decreased Mechanical Ventilation, Intensive Care Unit Admission, and In-Hospital Mortality in Hospitalized Patients With Coronavirus Disease 2019

Anesthesia and Analgesia, 2020
BACKGROUND: Coronavirus disease-2019 (COVID-19) is associated with hypercoagulability and increased thrombotic risk in critically ill patients. To our knowledge, no studies have evaluated whether aspirin use is associated with reduced risk of mechanical ...
J. Chow, A. Khanna, S. Kethireddy, D. Yamane, A. Levine, Amanda M. Jackson, M. McCurdy, A. Tabatabai, G. Kumar, P. Park, I. Benjenk, Jay Menaker, Nayab Ahmed, Evan Glidewell, Elizabeth Presutto, Shannon Cain, Naeha Haridasa, Wesley Field, Jacob G. Fowler, D. Trinh, Kathleen N. Johnson, Amanjyot Kaur, A. Lee, Kyle Sebastian, Allison Ulrich, S. Peña, R. Carpenter, S. Sudhakar, Pushpinder Uppal, Benjamin T. Fedeles, Aaron Sachs, Layth Dahbour, W. Teeter, Kenichi A. Tanaka, Samuel M. Galvagno, D. Herr, T. Scalea, Michael A. Mazzeffi   +37 more
semanticscholar   +1 more source

Aspirin “Allergy”-Induced Thrombocytopenia: A Case Report

Journal of Asthma and Allergy, 2021
Wei Fu, Shanshan Xu, Xiang Dong, Qing Xie, Yadong Gao Department of Allergology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, People’s Republic of ChinaCorrespondence: Yadong Gao; Wei FuDepartment of Allergology, Zhongnan Hospital of Wuhan ...
Fu W, Xu S, Dong X, Xie Q, Gao Y
doaj  

'Aspirin resistance' or treatment non-compliance: Which is to blame for cardiovascular complications?

Journal of Translational Medicine, 2008
Aspirin is one of the 'cornerstone' drugs in our current management of cardiovascular disorders. However, despite the prescription of aspirin recurrent vascular events still occur in 10–20% of patients.
Shantsila Eduard, Lip Gregory YH
doaj   +1 more source