Results 31 to 40 of about 372,006 (379)
Background/Purpose: Antiplatelet therapy is the cornerstone for acute ischemic stroke or transient ischemic attack (TIA). The purpose of this study was to conduct a meta-analysis to assess the efficacy and safety of P2Y12 receptor inhibitor plus aspirin ...
Wen-Yi Huang, Bruce Ovbiagele, Meng Lee
doaj
Anti-cancer effects and mechanism of actions of aspirin analogues in the treatment of glioma cancer [PDF]
INTRODUCTION: In the past 25 years only modest advancements in glioma treatment have been made, with patient prognosis and median survival time following diagnosis only increasing from 3 to 7 months.
A. A. Hill+312 more
core +1 more source
Essential thrombocythemia (ET) and polycythemia vera (PV) are myeloproliferative neoplasms (MPN) with an increased risk of arterial and venous thrombosis.
Andréas Perrier-Cornet+5 more
doaj +1 more source
Clinically, three phenotypes of intolerance to aspirin and other nonsteroidal anti-inflammatory drugs are distinguished: bronchospastic phenotype, urticaria/oedema and chronic hyperplastic eosinophilic sinusitis.
Iwona Grzelewska-Rzymowska+1 more
doaj +1 more source
The targets of aspirin in bladder cancer: bioinformatics analysis
Background The anti-carcinogenic properties of aspirin have been observed in some solid tumors. However, the molecular mechanism of therapeutic effects of aspirin on bladder cancer is still indistinct. We introduced a bioinformatics analysis approach, to
Xiao Li+10 more
doaj +1 more source
Background Studies have indicated that individuals taking aspirin have a reduced risk of cancers and have also established chemo-preventive benefit of aspirin in colorectal cancer. However, research on the association between aspirin use and the survival
Min-Chun Chuang+6 more
doaj +1 more source
Application of low dose aspirin in pre-eclampsia
Aspirin is widely used in the primary and secondary prevention of cardiovascular and cerebrovascular diseases. Low-dose aspirin is also widely used to prevent pre-eclampsia and fetal growth retardation in utero.
Yu Ren+4 more
doaj +1 more source
Background Our previous publication showed that 9% of patients with a history of myocardial infarction MI. could be labeled as aspirin resistant; all of these patients were aspirin resistant because of non-compliance.
Reeves Mathew+4 more
doaj +1 more source
In Silico screening of nonsteroidal anti-inflammatory drugs and their combined action on Prostaglandin H Synthase-1 [PDF]
The detailed kinetic model of Prostaglandin H Synthase-1 (PGHS-1) was applied to in silico screening of dose-dependencies for the different types of nonsteroidal anti-inflammatory drugs (NSAIDs), such as: reversible/irreversible, nonselective/selective ...
Demin, Oleg+5 more
core +4 more sources
Major bleeding is linked to poorer outcomes following cardiac surgery. Current guidelines recommend continuation of aspirin prior to coronary artery by‐pass graft (CABG) but the effect of continuing aspirin in patients with prior indication for aspirin ...
Christopher Little+5 more
doaj +1 more source