Results 41 to 50 of about 495,297 (403)

Aspirin with or without Clopidogrel after Transcatheter Aortic-Valve Implantation.

New England Journal of Medicine, 2020
BACKGROUND The effect of single as compared with dual antiplatelet treatment on bleeding and thromboembolic events after transcatheter aortic-valve implantation (TAVI) in patients who do not have an indication for long-term anticoagulation has not been ...
J. Brouwer, V. Nijenhuis, R. Delewi, R. Hermanides, W. Holvoet, C. Dubois, P. Frambach, B. de Bruyne, G. V. van Houwelingen, J. van der Heyden, P. Toušek, F. van der Kley, I. Buysschaert, C. Schotborgh, B. Ferdinande, P. van der Harst, J. Roosen, J. Peper, Frederick W F Thielen, L. Veenstra, D. R. Chan Pin Yin, M. Swaans, B. Rensing, A. W. van ’t Hof, L. Timmers, J. Kelder, P. Stella, J. Baan, J. T. ten Berg   +28 more
semanticscholar   +1 more source

Aspirin-dependent effects on purinergic P2Y1 receptor express [PDF]

, 2019
Chronic treatment with aspirin in healthy volunteers (HVs) is associated with recovery of adenosine diphosphate (ADP)-induced platelet activation. The purinergic P2Y1 receptor exerts its effects via a Gq-protein, which is the same biochemical pathway ...
Alemanno, Laura, Angiolillo, Dominick J, Ceccacci, Andrea, Frati, Luigi, Guarino, Maria Luisa, Guerriero, Raffaella, Mancone, Massimo, Massimi, Isabella, Pulcinelli, Fabio M   +8 more
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Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus

New England Journal of Medicine, 2018
BACKGROUND Diabetes mellitus is associated with an increased risk of cardiovascular events. Aspirin use reduces the risk of occlusive vascular events but increases the risk of bleeding; the balance of benefits and hazards for the prevention of first ...
L. Bowman, M. Mafham, K. Wallendszus, W. Stevens, G. Buck, J. Barton, K. Murphy, Theingi Aung, R. Haynes, J. Cox, A. Murawska, A. Young, M. Lay, Fang Chen, E. Sammons, Emma Waters, A. Adler, J. Bodansky, A. Farmer, R. Mcpherson, A. Neil, D. Simpson, R. Peto, C. Baigent, R. Collins, S. Parish, J. Armitage   +26 more
semanticscholar   +1 more source

Lower mortality rate in elderly patients with community-onset pneumonia on treatment with aspirin [PDF]

, 2015
BACKGROUND: Pneumonia is complicated by high rate of mortality and cardiovascular events (CVEs). The potential benefit of aspirin, which lowers platelet aggregation by inhibition of thromboxane A2 production, is still unclear. The aim of the study was to
Barilla', Francesco, Bertazzoni, Giuliano, Calvieri, Camilla, Cangemi, Roberto, Falcone, Marco, Farcomeni, Alessio, Palange, Paolo, Russo, Alessandro, Scarpellini, Maria Gabriella, Taliani, Gloria, Venditti, Mario, Violi, Francesco   +11 more
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Thrombosis and Aspirin: Clinical Aspect, Aspirin in Cardiology, Aspirin in Neurology, and Pharmacology of Aspirin [PDF]

Thrombosis, 2012
Acetyl salicylic acid or aspirin is one of the most famous drugs in the world. Aspirin has been increasingly used for prevention of cardiovascular events and is, particularly in recent decades, the most used nonsteroidal anti-inflammatory drug. Thus, it was necessary to have several contributions to precise the interest and the side effects of ...
openaire   +2 more sources

Association of Aspirin with Hepatocellular Carcinoma and Liver-Related Mortality.

New England Journal of Medicine, 2020
BACKGROUND More information is needed about the long-term effects of low-dose aspirin (≤160 mg) on incident hepatocellular carcinoma, liver-related mortality, and gastrointestinal bleeding in persons with chronic hepatitis B or hepatitis C virus ...
Tracey G. Simon, Ann-Sofi Duberg, S. Aleman, R. Chung, A. Chan, J. Ludvigsson   +5 more
semanticscholar   +1 more source

Aspirin resistance in patients with acute coronary syndrome. Part 2

Кардиоваскулярная терапия и профилактика, 2011
Aim. In patients with acute coronary syndrome (ACS), to investigate the prevalence of aspirin resistance, its clinical features, prognostic effects, and potential correction. Material and methods.
N. S. Frolova, R. M. Shakhnovich, E. M. Kaznacheeva, O. V. Sirotkina, A. B. Dobrovolskyi   +4 more
doaj   +1 more source

Apixaban Enhances Endogenous Fibrinolysis in Patients with Atrial Fibrillation [PDF]

, 2019
© The Author(s) 2019. Published by Oxford University Press on behalf of the European Society of Cardiology.AIMS: Approximately 20% of ischaemic stroke patients exhibit spontaneous arterial recanalization, attributable to endogenous fibrinolysis, which ...
Arachchillage, Deepa RJ, Farag, Mohamed, Gorog, Diana, Gue, Ying X., Lip, Gregory Y H, Spinthakis, Nikolaos, Srinivasan, Manivannan, Wellsted, David   +7 more
core   +3 more sources

Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly

New England Journal of Medicine, 2018
BACKGROUND Aspirin is a well‐established therapy for the secondary prevention of cardiovascular events. However, its role in the primary prevention of cardiovascular disease is unclear, especially in older persons, who have an increased risk.
J. McNeil, R. Wolfe, R. Woods, A. Tonkin, G. Donnan, Mark R. Nelson, C. Reid, J. Lockery, B. Kirpach, E. Storey, R. Shah, J. Williamson, K. Margolis, M. Ernst, W. Abhayaratna, N. Stocks, S. Fitzgerald, S. Orchard, R. Trevaks, L. Beilin, C. Johnston, J. Ryan, B. Radziszewska, M. Jelinek, M. Malik, C. Eaton, D. Brauer, G. Cloud, E. Wood, S. Mahady, S. Satterfield, R. Grimm, A. Murray   +32 more
semanticscholar   +1 more source

Low-dose aspirin for the prevention of preterm delivery in nulliparous women with a singleton pregnancy (ASPIRIN): a randomised, double-blind, placebo-controlled trial

The Lancet, 2020
BACKGROUND Preterm birth remains a common cause of neonatal mortality, with a disproportionately high burden in low-income and middle-income countries. Meta-analyses of low-dose aspirin to prevent pre-eclampsia suggest that the incidence of preterm birth
M. Hoffman, S. Goudar, B. Kodkany, M. Metgud, M. Somannavar, J. Okitawutshu, A. Lokangaka, A. Tshefu, C. Bose, A. Mwapule, Musaku Mwenechanya, E. Chomba, W. Carlo, J. Chicuy, L. Figueroa, A. Garcés, N. Krebs, S. Jessani, F. Zehra, S. Saleem, R. Goldenberg, K. Kurhe, P. Das, Archana B Patel, P. Hibberd, Emmah Achieng, P. Nyongesa, F. Esamai, E. Liechty, N. Goco, J. Hemingway-Foday, Janet L Moore, T. Nolen, E. Mcclure, M. Koso-thomas, M. Miodovnik, R. Silver, R. Derman, M. Bauserman, C. Bose, S. Bucher, W. Carlo, U. Charantimath, R. Derman, M. Ganachari, Noman Goco, Robert Goldenberg, S. Goudar, P. Hibberd, M. Hoffman, Narayan V. Honnungar, A. Kavi, B. Kodkany, N. Krebs, Y. K. Shashikanth, E. Liechty, Emily R Macguire, Ashalata A. Mallapur, E. Mcclure, Farnaz Naqvi, S. Naqvi, R. Nathan, T. Nolen, Suchita Parepalli, U. Ramadurg, R. Silver, Zahid Soomro, Sunil S. Vernekar, Dennis D Wallace   +68 more
semanticscholar   +1 more source