Results 51 to 60 of about 482,608 (393)

Decreased sensitivity to aspirin is associated with altered polyamine metabolism in human prostate cancer cells [PDF]

, 2015
Acknowledgments We thank NHS Grampian for financial support of this work.Peer reviewedPublisher ...
Cameron, Gary A., Li, Jun, Wallace, Heather M.   +2 more
core   +1 more source

Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly

New England Journal of Medicine, 2018
BACKGROUND Aspirin is a well‐established therapy for the secondary prevention of cardiovascular events. However, its role in the primary prevention of cardiovascular disease is unclear, especially in older persons, who have an increased risk.
J. McNeil, R. Wolfe, R. Woods, A. Tonkin, G. Donnan, Mark R. Nelson, C. Reid, J. Lockery, B. Kirpach, E. Storey, R. Shah, J. Williamson, K. Margolis, M. Ernst, W. Abhayaratna, N. Stocks, S. Fitzgerald, S. Orchard, R. Trevaks, L. Beilin, C. Johnston, J. Ryan, B. Radziszewska, M. Jelinek, M. Malik, C. Eaton, D. Brauer, G. Cloud, E. Wood, S. Mahady, S. Satterfield, R. Grimm, A. Murray   +32 more
semanticscholar   +1 more source

Lower mortality rate in elderly patients with community-onset pneumonia on treatment with aspirin [PDF]

, 2015
BACKGROUND: Pneumonia is complicated by high rate of mortality and cardiovascular events (CVEs). The potential benefit of aspirin, which lowers platelet aggregation by inhibition of thromboxane A2 production, is still unclear. The aim of the study was to
Barilla', Francesco, Bertazzoni, Giuliano, Calvieri, Camilla, Cangemi, Roberto, Falcone, Marco, Farcomeni, Alessio, Palange, Paolo, Russo, Alessandro, Scarpellini, Maria Gabriella, Taliani, Gloria, Venditti, Mario, Violi, Francesco   +11 more
core   +1 more source

Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and Meta-analysis

Journal of the American Medical Association (JAMA), 2019
Importance The role for aspirin in cardiovascular primary prevention remains controversial, with potential benefits limited by an increased bleeding risk.
Sean Zheng, A. Roddick
semanticscholar   +1 more source

Aspirin Use Is Associated With Decreased Mechanical Ventilation, Intensive Care Unit Admission, and In-Hospital Mortality in Hospitalized Patients With Coronavirus Disease 2019

Anesthesia and Analgesia, 2020
BACKGROUND: Coronavirus disease-2019 (COVID-19) is associated with hypercoagulability and increased thrombotic risk in critically ill patients. To our knowledge, no studies have evaluated whether aspirin use is associated with reduced risk of mechanical ...
J. Chow, A. Khanna, S. Kethireddy, D. Yamane, A. Levine, Amanda M. Jackson, M. McCurdy, A. Tabatabai, G. Kumar, P. Park, I. Benjenk, Jay Menaker, Nayab Ahmed, Evan Glidewell, Elizabeth Presutto, Shannon Cain, Naeha Haridasa, Wesley Field, Jacob G. Fowler, D. Trinh, Kathleen N. Johnson, Amanjyot Kaur, A. Lee, Kyle Sebastian, Allison Ulrich, S. Peña, R. Carpenter, S. Sudhakar, Pushpinder Uppal, Benjamin T. Fedeles, Aaron Sachs, Layth Dahbour, W. Teeter, Kenichi A. Tanaka, Samuel M. Galvagno, D. Herr, T. Scalea, Michael A. Mazzeffi   +37 more
semanticscholar   +1 more source

Aspirin “Allergy”-Induced Thrombocytopenia: A Case Report

Journal of Asthma and Allergy, 2021
Wei Fu, Shanshan Xu, Xiang Dong, Qing Xie, Yadong Gao Department of Allergology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, People’s Republic of ChinaCorrespondence: Yadong Gao; Wei FuDepartment of Allergology, Zhongnan Hospital of Wuhan ...
Fu W, Xu S, Dong X, Xie Q, Gao Y
doaj  

Thrombosis and Aspirin: Clinical Aspect, Aspirin in Cardiology, Aspirin in Neurology, and Pharmacology of Aspirin [PDF]

Thrombosis, 2012
Acetyl salicylic acid or aspirin is one of the most famous drugs in the world. Aspirin has been increasingly used for prevention of cardiovascular events and is, particularly in recent decades, the most used nonsteroidal anti-inflammatory drug. Thus, it was necessary to have several contributions to precise the interest and the side effects of ...
openaire   +3 more sources

Effect of Aspirin on All‐Cause Mortality in the Healthy Elderly

New England Journal of Medicine, 2018
BACKGROUND In the primary analysis of the Aspirin in Reducing Events in the Elderly (ASPREE) trial, now published in the Journal, we report that the daily use of aspirin did not provide a benefit with regard to the primary end point of disability‐free ...
J. McNeil, M. Nelson, R. Woods, J. Lockery, R. Wolfe, C. Reid, B. Kirpach, R. Shah, D. Ives, E. Storey, J. Ryan, A. Tonkin, A. Newman, J. Williamson, K. Margolis, M. Ernst, W. Abhayaratna, N. Stocks, S. Fitzgerald, S. Orchard, R. Trevaks, L. Beilin, G. Donnan, P. Gibbs, C. Johnston, B. Radziszewska, R. Grimm, A. Murray   +27 more
semanticscholar   +1 more source

Low-dose aspirin for the prevention of preterm delivery in nulliparous women with a singleton pregnancy (ASPIRIN): a randomised, double-blind, placebo-controlled trial

The Lancet, 2020
BACKGROUND Preterm birth remains a common cause of neonatal mortality, with a disproportionately high burden in low-income and middle-income countries. Meta-analyses of low-dose aspirin to prevent pre-eclampsia suggest that the incidence of preterm birth
M. Hoffman, S. Goudar, B. Kodkany, M. Metgud, M. Somannavar, J. Okitawutshu, A. Lokangaka, A. Tshefu, C. Bose, A. Mwapule, Musaku Mwenechanya, E. Chomba, W. Carlo, J. Chicuy, L. Figueroa, A. Garcés, N. Krebs, S. Jessani, F. Zehra, S. Saleem, R. Goldenberg, K. Kurhe, P. Das, Archana B Patel, P. Hibberd, Emmah Achieng, P. Nyongesa, F. Esamai, E. Liechty, N. Goco, J. Hemingway-Foday, Janet L Moore, T. Nolen, E. Mcclure, M. Koso-thomas, M. Miodovnik, R. Silver, R. Derman, M. Bauserman, C. Bose, S. Bucher, W. Carlo, U. Charantimath, R. Derman, M. Ganachari, Noman Goco, Robert Goldenberg, S. Goudar, P. Hibberd, M. Hoffman, Narayan V. Honnungar, A. Kavi, B. Kodkany, N. Krebs, Y. K. Shashikanth, E. Liechty, Emily R Macguire, Ashalata A. Mallapur, E. Mcclure, Farnaz Naqvi, S. Naqvi, R. Nathan, T. Nolen, Suchita Parepalli, U. Ramadurg, R. Silver, Z. Soomro, Sunil S. Vernekar, Dennis D Wallace   +68 more
semanticscholar   +1 more source

'Aspirin resistance' or treatment non-compliance: Which is to blame for cardiovascular complications?

Journal of Translational Medicine, 2008
Aspirin is one of the 'cornerstone' drugs in our current management of cardiovascular disorders. However, despite the prescription of aspirin recurrent vascular events still occur in 10–20% of patients.
Shantsila Eduard, Lip Gregory YH
doaj   +1 more source