Results 51 to 60 of about 312,145 (352)

Effect of aspirin in "aspirin sensitive" patients. [PDF]

BMJ, 1984
Eighteen patients with a history of urticaria or asthma, or both, induced by aspirin were studied before and after provocation of symptoms with aspirin. The plasma prostaglandin F2 alpha concentration, which was characteristically raised before challenge, fell significantly at the time of adverse reactions.
A W Frankland, L. J. F. Youlten, S. I. Asad, D. M. Kemeny, Maurice Lessof   +4 more
openaire   +3 more sources

Is Long-Term Low-Dose Aspirin Therapy Associated with Renal Dysfunction in Patients with Type 2 Diabetes? JPAD2 Cohort Study. [PDF]

PLoS ONE, 2016
BACKGROUND:Low-dose aspirin is widely recommended for patients at high risk for cardiovascular disease (CVD); however, it remains uncertain whether long-term treatment adversely affects renal function in patients with diabetes.
Sadanori Okada, Takeshi Morimoto, Hisao Ogawa, Mio Sakuma, Hirofumi Soejima, Masafumi Nakayama, Hideaki Jinnouchi, Masako Waki, Yasuhiro Akai, Hitoshi Ishii, Yoshihiko Saito, Investigators for the Japanese Primary Prevention of Atherosclerosis with Aspirin for Diabetes trial   +11 more
doaj   +1 more source

Effect of Aspirin on Disability‐free Survival in the Healthy Elderly

New England Journal of Medicine, 2018
BACKGROUND Information on the use of aspirin to increase healthy independent life span in older persons is limited. Whether 5 years of daily low‐dose aspirin therapy would extend disability‐free life in healthy seniors is unclear.
J. McNeil, R. Woods, M. Nelson, C. Reid, B. Kirpach, R. Wolfe, E. Storey, R. Shah, J. Lockery, A. Tonkin, A. Newman, J. Williamson, K. Margolis, M. Ernst, W. Abhayaratna, N. Stocks, S. Fitzgerald, S. Orchard, R. Trevaks, L. Beilin, G. Donnan, P. Gibbs, C. Johnston, J. Ryan, B. Radziszewska, R. Grimm, A. Murray   +26 more
semanticscholar   +1 more source

Clinical Effectiveness and Safety of Aspirin for Venous Thromboembolism Prophylaxis After Total Hip and Knee Replacement: A Systematic Review and Meta-analysis of Randomized Clinical Trials.

JAMA Internal Medicine, 2020
Importance Patients undergoing total hip replacement (THR) and total knee replacement (TKR) receive venous thromboembolism (VTE) pharmacoprophylaxis. It is unclear which anticoagulant is preferable.
G. Matharu, S. Kunutsor, A. Judge, A. Blom, M. Whitehouse   +4 more
semanticscholar   +1 more source

Preoperative aspirin use and acute kidney injury after cardiac surgery: A propensity-score matched observational study. [PDF]

PLoS ONE, 2017
BACKGROUND:The association between preoperative aspirin use and postoperative acute kidney injury (AKI) in cardiovascular surgery is unclear. We sought to evaluate the effect of preoperative aspirin use on postoperative AKI in cardiac surgery.
Min Hur, Chang-Hoon Koo, Hyung-Chul Lee, Sun-Kyung Park, Minkyung Kim, Won Ho Kim, Jin-Tae Kim, Jae-Hyon Bahk   +7 more
doaj   +1 more source

Polypill with or without Aspirin in Persons without Cardiovascular Disease.

New England Journal of Medicine, 2020
BACKGROUND A polypill comprising statins, multiple blood-pressure-lowering drugs, and aspirin has been proposed to reduce the risk of cardiovascular disease.
S. Yusuf, P. Joseph, A. Dans, P. Gao, K. Teo, D. Xavier, P. López-Jaramillo, K. Yusoff, A. Santoso, H. Gamra, S. Talukder, Courtney Christou, P. Girish, K. Yeates, F. Xavier, G. Dagenais, Catalina Rocha, T. McCready, J. Tyrwhitt, J. Bosch, P. Pais   +20 more
semanticscholar   +1 more source

Aspirin and Stroke

Archives of Neurology, 1990
In our recent article, 1 we reviewed the available evidence on aspirin and other antiplatelet agents in the secondary and primary prevention of cardiovascular disease. We concluded that low-dose aspirin should be a possible adjunct, not an alternative, to coronary risk factor management and, in view of its possible side effects, should be prescribed ...
Buring, J, Hennekens, C, Sandercock, P, Collins, R, Peto, R   +4 more
openaire   +3 more sources

occumb: An R package for site occupancy modeling of eDNA metabarcoding data

Population Ecology, EarlyView.
This study introduces a new R package, occumb, for the convenient application of site occupancy modeling using environmental DNA (eDNA) metabarcoding data. We outline a data analysis workflow, including data setup, model fitting, model assessment, and comparison of potential study settings based on model predictions, all of which can be performed using
Keiichi Fukaya, Yuta Hasebe
wiley   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Aspirin: yesterday, today, and tomorrow

Pediatria i Medycyna Rodzinna, 2014
Clinical utility of aspirin (acetylsalicylic acid, ASA) is one of the more important issues in the primary and secondary prevention of cardiovascular disease.
Marina Nikołajewna Dołżenko
doaj   +1 more source