Results 231 to 240 of about 88,625 (333)
Angewandte Chemie International Edition, EarlyView.We present a nanodroplet array platform that integrates solid‐phase synthesis, MALDI‐MS analysis, and cell‐based screening. Using nanoliter droplets, we synthesized and tested 325 potential MEK inhibitors and identified 46 active compounds. This miniaturized approach combines chemistry and biology on a single chip, reducing time, cost, and material use
Maximilian Seifermann +10 more
wiley +1 more source
The frequency of aspirin resistance by a modified thrombelastography method and its relationship with clinical and laboratory parameters in patients with stable coronary artery disease [PDF]
, 2012 Durmuş Yıldıray Şahin
openalex +1 more source
Archaeology in Oceania, EarlyView.ABSTRACT Raw materials are used to characterise the early settlement of Aotearoa Te Wai Pounamu New Zealand by Māori. Current models suggest change in raw material use over time occurred in response to changing social organisation and reduced resource availability. However, few studies have examined spatial variation in raw material use.
Rebecca Phillipps +3 more
wiley +1 more source
Dual antiplatelet therapy in patients with aspirin resistance following coronary artery bypass grafting: study protocol for a randomized controlled trial [NCT01159639] [PDF]
, 2012 Hrvoje Gašparović +5 more
openalex +1 more source
Arthritis &Rheumatology, EarlyView.Objective Tumornecrosis factor inhibitors (TNFi) have significantly improved rheumatoid arthritis (RA) management, yet variability in patient response remains a substantial challenge, with approximately 40% of patients discontinuing TNFi due to nonresponse or adverse effects.
Chuan Fu Yap +12 more
wiley +1 more source
Antiphospholipid Syndrome: An Antibody‐Mediated Disease With Emerging Therapeutic Opportunities
Arthritis &Rheumatology, EarlyView.Antiphospholipid syndrome (APS) is an autoimmune thromboinflammatory disease characterized by vascular thrombosis, pregnancy morbidity, and other manifestations driven by antiphospholipid autoantibodies. In this review, we present a clinical case that illustrates some diagnostic and therapeutic challenges in managing severe, relapsing APS ...
Thalia G. Newman, Jason S. Knight
wiley +1 more source
GENDER DIFFERENCES OF ASPIRIN RESISTANCE IN PATIENTS WITH CORONARY ARTERY DISEASE [PDF]
, 2012 Zhili Jiang, Yanfang Li
openalex +1 more source
Arthritis &Rheumatology, Accepted Article.Objective International criteria for antiphospholipid syndrome (APS) include lupus anticoagulant (LA), anticardiolipin (aCL) immunoglobulin (Ig) G and IgM, and anti‐β2‐glycoprotein I (β2GPI) IgG and IgM. However, evidence supporting their prognostic value or treatment efficacy in improving live birth rates is limited.
Megumi Nonobe +8 more
wiley +1 more source
Association of Aspirin Resistance with Increased Mortality in Ischemic Stroke. [PDF]
J Nutr Health Aging, 2019 Jing Y, Yue X, Yang S, Li S.
europepmc +1 more source
Incidence of Aspirin Resistance in the Patient Group of a University Hospital in Korea
, 2008 Young Kyung Lee +3 more
openalex +2 more sources