Results 251 to 260 of about 88,633 (281)
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Future Cardiology, 2005
“The clinical impact of aspirin resistance with cardiovascular events is now becoming evident, with aspirin nonresponders having nearly a threefold increased risk of cardiovascular death” Aspirin resistance is an increasingly recognized phenomenon denoting a diminished platelet inhibitory effect of aspirin.
Sasidhar, Guthikonda, Neal S, Kleiman
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“The clinical impact of aspirin resistance with cardiovascular events is now becoming evident, with aspirin nonresponders having nearly a threefold increased risk of cardiovascular death” Aspirin resistance is an increasingly recognized phenomenon denoting a diminished platelet inhibitory effect of aspirin.
Sasidhar, Guthikonda, Neal S, Kleiman
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Aspirin resistance in atherosclerosis
Current Atherosclerosis Reports, 2008Clinically, aspirin resistance is defined as the failure of aspirin therapy to prevent an acute vascular thrombotic event despite regular intake of appropriate doses. In the laboratory, aspirin resistance encompasses the drug's failure to attain a particular level of platelet inhibition. From a clinical standpoint, the inability of aspirin to prevent a
Price, Blair, Jane E, Freedman
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Aspirin resistance and other aspirin-related concerns
Neurological Sciences, 2015Aspirin is a widely used medication and has become a cornerstone for treating cardiovascular disease. Aspirin can significantly reduce the incidence of cardiovascular ischemic events, recurrence and mortality, thereby improving the long-term prognosis of patients.
Gaoyu, Cai +5 more
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Aspirin and aspirin resistance in coronary artery disease
Current Opinion in Pharmacology, 2013Aspirin is still the mainstay of antiplatelet therapy in the secondary prevention of coronary artery disease. However certain patients do not benefit from the antithrombotic effects of aspirin. The phenomenon of so-called aspirin resistance can be considered from the clinical and laboratory perspective.
Charalampos, Kasmeridis +2 more
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Aspirin resistance in stroke: 2004 [PDF]
Journal of the Neurological Sciences, 2005 Aspirin is a well-established medication in the treatment of atherothrombotic vascular disease. However, despite aspirin treatment a substantial number of patients experience recurring ischaemic episodes. Aspirin resistance denotes those situations when it is unable to protect individuals from thrombotic complications, or when it fails to produce an ...
Sztriha László Krisztián +2 more
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Aspirin Resistance: Does It Exist?
Seminars in Thrombosis and Hemostasis, 2007Aspirin irreversibly inhibits platelet cyclooxygenase-1 (COX-1). Aspirin sensitivity can be measured easily by its inhibition of arachidonic acid (AA) -induced platelet aggregation. Aspirin resistance has to be defined by its inability to inhibit COX-1. By using this definition, aspirin resistance very likely does not exist. A specific rapid laboratory
Rao, Gundu H.R., Michiels, Jan J.
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Pharmacological reports : PR, 2010
Aspirin protects many though not all patients from acute cardiovascular events. It is generally accepted that such prophylactic effect depends mainly on the antithrombotic action involving inhibition of thromboxane A(2) production and platelet aggregation.
Andrzej, Szczeklik +4 more
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Aspirin protects many though not all patients from acute cardiovascular events. It is generally accepted that such prophylactic effect depends mainly on the antithrombotic action involving inhibition of thromboxane A(2) production and platelet aggregation.
Andrzej, Szczeklik +4 more
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Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2004
Aspirin is an effective antithrombotic agent for many patients. However, patients taking aspirin might exhibit variable responses to in vitro tests for platelet aggregation and might experience breakthrough thromboembolic events. Although this phenomenon has been called aspirin resistance, the lack of an uniform definition or agreement on diagnostic ...
Mehmet Birhan, Yilmaz +2 more
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Aspirin is an effective antithrombotic agent for many patients. However, patients taking aspirin might exhibit variable responses to in vitro tests for platelet aggregation and might experience breakthrough thromboembolic events. Although this phenomenon has been called aspirin resistance, the lack of an uniform definition or agreement on diagnostic ...
Mehmet Birhan, Yilmaz +2 more
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Diagnostics for Aspirin Resistance
Molecular Diagnosis & Therapy, 2008Paul A, Gurbel +2 more
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Pharmacogenetics of aspirin resistance: a comprehensive systematic review
British Journal of Clinical Pharmacology, 2008Albert Ferro
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