Results 241 to 250 of about 4,614,031 (312)

Integrating artificial intelligence and manual curation to enhance bioassay annotations in ChEMBL. [PDF]

J Cheminform
Smit I, Adasme MF, Manners E, Corbett S, Bosc N, Do HM, Leach AR, O'Boyle NM, Zdrazil B.   +8 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Guidelines and Diagnostic Assays for <i>Mycoplasma genitalium</i>. [PDF]

Open Forum Infect Dis
Ardizzone CM, Jordan SJ.
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Lack of harmonisation in immunological data: challenges in synthesising data during the COVID-19 pandemic. [PDF]

EBioMedicine
Shaver N, Colijn C, Heffernan J, Asamoah GD, Piggott T, Cooper C, Bagheri S, Crawley AM, Kagina BM, Bowdish DME, Langlois MA, Little J.   +11 more
europepmc   +1 more source

One-Tube RPA-CRISPR/Cas12a Assays for Rapid and Visual Detection of <i>Pseudomonas fluorescens</i> and <i>Bacillus cereus</i>. [PDF]

Foods
Yang C, Wang G, Zhou X, Song J, Luo X, Liu H, Zeng H, Wu W, Zhao X, Wang J.   +9 more
europepmc   +1 more source

A DNA-Based Binding Assay for the m⁶A-RNA Reader Proteins. [PDF]

Chembiochem
Bedi RK, Caflisch A.
europepmc   +1 more source

IL40: A Newly Described Cytokine With Conflicting Measurements and Detection Variability-Are There Different Forms? [PDF]

Scand J Immunol
Euler N, Huang W, Hemmingsson P, Juto A, Hellbacher E, Klareskog L, Malmström V, Gunnarsson I, Baecklund E, Grönwall C.   +9 more
europepmc   +1 more source