Results 111 to 120 of about 8,331,370 (291)
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
General Assembly open meetings law
, 2004 Title from caption of PDF document (viewed Jan. 26, 2006).; "This ... Brief is an update of an earlier Brief on this subject dated November 8, 2002 (Volume 124 Issue 11)."; "October 4, 2004."; Harvested from the web on 1/27/06This brief explains how ...
Goshay, Pamela.
core
Decision on the “Convening of Mid-Year Sessions of the Assembly of the African Union (July Sessions)” Doc. Assembly/Au/17(Xv)Add.11 [PDF]
, 2005 Decision Assembly/AU/Dec.63(IV) on the Framework for The Organization of Future Summits adopted at its Fourth Ordinary Session held in Abuja, Nigeria, in January ...
The Assembly
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Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
, 1996 This book contains reports from the national officers and program directors of The Links, Inc., about the activities of the national level of the organization from 1994-1996. It was presented to the 30th National Assembly.
Links, Inc. National Assembly.
core
Jixie chuandong, 2021 In order to determine the assembly quality of a certain type of gearbox， the common assembly faults of gearbox are briefly introduced based on the internal structure of gearbox， the characteristics frequencies of common faults of each gear and bearing in
Zheng Zou +5 more
doaj
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Application of Vision Language Models in the Shoe Industry
Engineering ProceedingsThe confluence of computer vision and natural language processing has yielded powerful vision language models (VLMs) capable of multimodal understanding. We applied state-of-the-art VLMs for quality monitoring of the shoe assembly industry. By leveraging
Hsin-Ming Tseng, Hsueh-Ting Chu
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source