Results 91 to 100 of about 8,331,370 (291)

Research on Crucial Assembly Feature Recognition of Mechanical Assembly Process Based on Complex Network and TOPSIS-GRA

IEEE Access
As the last link of product manufacturing, assembly determines the quality of mutual cooperation between parts, which is directly related to the quality of the product.
Dongyue Qu, Chaoyun Gu, Guangyu Zhou, Wenchao Liang, Yuting Zhang   +4 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Quality Matters overview

, 2016
The presentation provides overview of the Quality Matters services and best practices.We do not provide public access to this presentation.
Quality Matters
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Defect prediction model for wrapping machines assembly [PDF]

, 2020
Purpose – Development of a defect prediction model for the assembly of wrapping machines. Design/methodology/approach – The assembly process of wrapping machines is firstly decomposed into several steps, called workstations, each one potentially ...
genta gianfranco, franceschini fiorenzo, galetto maurizio, verna elisa   +3 more
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Analysis of reconfigurable assembly system framing systems in automotive industry

MATEC Web of Conferences, 2017
Current trend in automotive industry shows increasing demand for multiple models with lean production. Prior to that, automotive manufacturing systems evolved from mass production to flexible automation.
Md Zain Mohamad Zamri, Abdul Rani Ahmad Majdi, Abd Majid Mohd Amin   +2 more
doaj   +1 more source

Regional sequence expansion or collapse in heterozygous genome assemblies.

PLoS Computational Biology, 2020
High levels of heterozygosity present a unique genome assembly challenge and can adversely impact downstream analyses, yet is common in sequencing datasets obtained from non-model organisms.
Kathryn C Asalone, Kara M Ryan, Maryam Yamadi, Annastelle L Cohen, William G Farmer, Deborah J George, Claudia Joppert, Kaitlyn Kim, Madeeha Froze Mughal, Rana Said, Metin Toksoz-Exley, Evgeny Bisk, John R Bracht   +12 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Oregon DEQ air quality monitoring ... annual report

, 1998
Covers OCLC #42360784, OCLC #1024315364, OCLC #12281291921998-Title from cover.Mode of access: Internet from the Oregon Government Publications Collection.This archived document is maintained by the Oregon State Library as part of the Oregon Documents ...

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