Results 61 to 70 of about 8,331,370 (291)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Final recommendations report [PDF]
, 2014 This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF cover (viewed on June 5, 2014)Report in ...
core
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Research on assembly reliability control technology for computer numerical control machine tools
Advances in Mechanical Engineering, 2017 Nowadays, although more and more companies focus on improving the quality of computer numerical control machine tools, its reliability control still remains as an unsolved problem.
Yan Ran, Genbao Zhang, Jihong Pang
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
A comparative evaluation of genome assembly reconciliation tools
Genome Biology, 2017 Background The majority of eukaryotic genomes are unfinished due to the algorithmic challenges of assembling them. A variety of assembly and scaffolding tools are available, but it is not always obvious which tool or parameters to use for a specific ...
Hind Alhakami +2 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
(Re)assembling air quality science: Exploring air quality knowledge production
, 2023 In this thesis I critically examine the production of knowledge about air quality. I do so to explore how air quality knowledge is produced, and critically engage with how we can reconfigure our relations with the air to begin to address air inequalities. I draw upon my direct involvement in three different forms of doing air quality science.
openaire +2 more sources
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Technological Quality Assurance of Assembling
Izvestiya MGTU MAMI, 2008 The paper offers the concept of system examination of product-technology-equipment precision interaction. This concept is intended to develop a general methodology of technological object creation. It includes the sections of precision analysis of output accuracy parameter configuration for assembly and technological process and assembly equipment ...
openaire +1 more source