Results 51 to 60 of about 1,631,483 (261)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

FIQWS Fall 2018: Phase 2 Assignment Prompt The Exploratory Essay [PDF]

open access: yes, 2018
This phase two writing assignment prompt for FIQWS 10003 - HA1 WCGI History & Culture and FIQWS 10103 - HA1 Composition for WCGI History & Culture (fall 2018) provides guidelines for writing an Exploratory Essay in which students will consider the ideas ...
Pringle, Sabina, Watson, Missy
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Integrating Course Material and Application: A Progressive Writing Assignment Applied to an Astrochemistry Tutorial

open access: yesPrompt, 2018
A major challenge in teaching is helping students integrate course concepts to understand the big picture of a field and apply those concepts in new situations.
Olivia H. Wilkins, Camillus F. Buzard
doaj   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Writing for Nonprofits in a Professionally-Oriented Institution: Using Rhetorical Genre Studies to Teach Flexibility

open access: yesPrompt, 2019
Teaching rhetorical flexibility within a nonprofit environment to professionally-oriented students can be challenging because the seemingly transactional genres of nonprofit communication, such as grant applications, do not appear to invite improvisation.
Kathryn J. Gindlesparger
doaj   +1 more source

Analyzing a memoir of disability: Utilizing a group writing assignment to increase applicability and comprehension of course material

open access: yesPrompt, 2020
"Analyzing a Memoir of Disability" is a semester-long project that promotes learning about disability and culture through group reading and writing about a single memoir. Students in an Introduction to Rehabilitation and Human Services course completed a
Meghan Owenz
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Composing Comes Alive: Dramatic Presentations in the Writing Classroom

open access: yesPrompt, 2019
In creating and presenting a collaborative dramatic presentation of a literary text, composition students bring "The Yellow Wallpaper" to life through close reading, literary analysis and synthesis, recursive multi-modal writing, and group performance ...
Ann E. Wallace
doaj   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

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