Results 51 to 60 of about 156,392 (346)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

A collaborative action research project to support Mathematics and Science PGCE students with Masters level writing [PDF]

, 2010
Since 2005, Post Graduate Certificate in Education (PGCE) courses in England and Wales have been awarded at Masters level which requires students to be able to write reflectively in an academic style in the discipline of Social Science.
Forsythe, Sue, Tas, Maarten
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Undergraduate science writing performance and perceptions following an online guided writing module

Discover Education
Undergraduate students often struggle with scientific communication, particularly in writing clear and concise lab reports. A retrospective cohort study was conducted in a multi-section Anatomy and Physiology laboratory course to examine patterns in ...
Amanda C. Gunlefinger, Hannah R. Smith, Jeffrey A. Klemens, Nanette J. Tomicek   +3 more
doaj   +1 more source

Impact of basic medical writing workshop on case report writing by post-graduate anaesthesia trainees: A pilot study

Indian Journal of Anaesthesia, 2018
Background and Aims: Research is an integral component of medical education and practice. However, the art of medical writing remains neglected. Case report writing marks foray into the world of publications and presentations.
Anjana S Wajekar, Sweta V Salgaonkar, Indrani H Chincholi, Anita N Shetty   +3 more
doaj   +1 more source

A methodology for enhancing student writing in the discipline through complementary and collaborative working between central and school based writing development provision [PDF]

, 2014
Academic literacies theory argues that academic writing is currently caught up in unequal power relationships which 'problematize the student' (Lea and Street 1998) and thus argues for a change in focus from a 'skills' model to the adoption of a more ...
Johnson, S, Trafford, S
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Entering into dialogue with the taboo: Reflective writing in a social work human sexuality course

Journal of Writing Research, 2012
This paper examines a unique reflective writing assignment used in an undergraduate social work course on human sexuality. We ask what new understandings reflective writing mediates (Vygotsky, 1978) regarding sexual orientation, gender identity, and ...
Heather Killelea McEntarfer, David Skiba & Sarah A. Robert
doaj