Results 51 to 60 of about 1,879,088 (284)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Frontiers in Aging NeuroscienceIntroductionThe finding that familiarity can support associative memory by unitizing the to -be-learned items into a novel representation has been widely accepted, but its effects on overall performance of associative memory and recollection are still ...
Zejun Liu +5 more
doaj +1 more source
Frontiers in Psychology, 2015 The present study combines behavioral observations of memory (deferred imitation after a brief delay of 30 minutes and after a long delay of 2-3 weeks) and electrophysiological (Event-Related Potentials, ERP) measures of associative memory as well as ...
Emelie eNordqvist +5 more
doaj +1 more source
Generalizations of the Hamming Associative Memory [PDF]
Neural Processing Letters, 2001 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Hassoun, Mohamad H., Watta, Paul
openaire +3 more sources
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
What associative learning in insects tells us about the evolution of learning and fixed behavior [PDF]
, 2015 Contemporary models for the evolution of learning suggest that environmental predictability plays a critical role in whether learning is expected to evolve in a particular species, a claim originally made over 50 years ago.
Hollis, Karen, Guillette, Lauren
core +3 more sources
Frontiers in Aging Neuroscience, 2020 Associative memory is one of the first cognitive functions negatively affected by healthy and pathological aging processes. Non-invasive brain stimulation (NIBS) techniques are easily administrable tools to support memory.
Katharina Klink +3 more
doaj +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Altered development of hippocampus-dependent associative learning following early-life adversity
Developmental Cognitive Neuroscience, 2019 Little is known about how childhood adversity influences the development of learning and memory and underlying neural circuits. We examined whether violence exposure in childhood influenced hippocampus-dependent associative learning and whether ...
Hilary K. Lambert +5 more
doaj +1 more source