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Journal of AsthmaObjective: The obese-asthma phenotype has gradually increased in the last few years. We aimed to assess the differences between obese and non-obese patients with asthma. Methods: This research is a subanalysis of the Turkish Adult Asthma Registry (TAAR).
Ayse Feyza Aslan +2 more
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Asthma phenotypes and endotypes
Minerva Medica, 2021Asthma is a complex disorder characterized by expiratory airflow limitation, wheeze, shortness of breath, chest tightness and cough, which can vary over time and in intensity. Being highly heterogeneous, asthma was characterized and classified in several asthma phenotypes and endotypes from 1947 until today.
Fabio Lm, Ricciardolo +3 more
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Phenotypes and Endotypes in Asthma
2023Asthma is a broadly encompassing diagnosis of airway inflammation with significant variability in presentation and response. Advances in molecular techniques and imaging have unraveled the delicate mechanistic tapestry responsible for the underlying inflammatory pathways in asthma. The elucidation of biomarkers and cellular components specific to these
Amanda P, McIntyre, Ravi K, Viswanathan
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Current Opinion in Internal Medicine, 2007
Asthma is a heterogeneous disorder presenting with many phenotypes. Precise phenotypic definition has eluded the medical research community for years, despite recognition of different disease subtypes. Improved phenotypic characterization and knowledge of underlying pathobiology is necessary for linkage of specific genotypes with clinical disease ...
James, Kiley +2 more
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Asthma is a heterogeneous disorder presenting with many phenotypes. Precise phenotypic definition has eluded the medical research community for years, despite recognition of different disease subtypes. Improved phenotypic characterization and knowledge of underlying pathobiology is necessary for linkage of specific genotypes with clinical disease ...
James, Kiley +2 more
openaire +2 more sources
Asthma phenotypes and endotypes
Current Opinion in Pulmonary Medicine, 2013It is increasingly clear that asthma is not a single disease, but a disorder with vast heterogeneity in pathogenesis, severity, and treatment response. In this review, we discuss the present understanding of different asthma phenotypes and endotypes, and the prospects of personalized medicine for asthma.The recognition of diverse biological backgrounds
Ting-Yu, Lin +2 more
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Current Opinion in Pediatrics, 2012
There is currently limited ability to identify which infants and young children with recurrent wheezing will ultimately develop persistent asthma. In addition, it is not clear how risk factors influence the development of asthma in later childhood and adulthood.
Kelly, Cowan, Theresa W, Guilbert
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There is currently limited ability to identify which infants and young children with recurrent wheezing will ultimately develop persistent asthma. In addition, it is not clear how risk factors influence the development of asthma in later childhood and adulthood.
Kelly, Cowan, Theresa W, Guilbert
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The investigation of asthma phenotypes
Current Opinion in Allergy & Clinical Immunology, 2011Asthma is a heterogeneous disease constituted by overlapping separate syndromes. This review discusses recent published data relevant to asthma and severe asthma classification, resting either on the 'candidate' approach based on criteria chosen by experts or on the 'exploratory' approach based on unsupervised statistical methods.Following the ...
Siroux, Valérie +1 more
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Investigating the asthma phenotype
Clinical & Experimental Allergy, 1998W. O. C. Cookson and L.
Cookson, W., Palmer, L.
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The Journal of Allergy and Clinical Immunology: In Practice, 2014
Allergic asthma is the most common asthma phenotype. It usually is defined by the presence of sensitization to environmental allergens, although a clinical correlation between exposure and symptoms further supports the diagnosis. The average age of onset of allergic asthma is younger than that of nonallergic asthma.
Michael, Schatz, Lanny, Rosenwasser
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Allergic asthma is the most common asthma phenotype. It usually is defined by the presence of sensitization to environmental allergens, although a clinical correlation between exposure and symptoms further supports the diagnosis. The average age of onset of allergic asthma is younger than that of nonallergic asthma.
Michael, Schatz, Lanny, Rosenwasser
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Paediatric Respiratory Reviews, 2010
The phenotype is the result of the observable characteristics of a subject resulting from the interactions between a genotype and its environment. Phenotyping asthmatic patients is a current search to better capture the heterogeneity of this disease with potential overlaps with other chronic bronchial disease such as COPD.
Pascal, Chanez +2 more
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The phenotype is the result of the observable characteristics of a subject resulting from the interactions between a genotype and its environment. Phenotyping asthmatic patients is a current search to better capture the heterogeneity of this disease with potential overlaps with other chronic bronchial disease such as COPD.
Pascal, Chanez +2 more
openaire +3 more sources