Results 171 to 180 of about 789,460 (209)
Some of the next articles are maybe not open access.
Adiponectin in Asthma: Implications for Phenotyping
Current Protein & Peptide Science, 2015Asthma is a heterogeneous inflammatory airway disease, which exhibits multiple phenotypes, mainly defined by a combination of different clinical features. Asthma phenotypes include age at onset, smoking status, exacerbations frequency, and co-existence of obesity. Links between specific biological pathways and phenotypes are emerging.
Nigro E +7 more
openaire +3 more sources
What is an “eosinophilic phenotype” of asthma?
Journal of Allergy and Clinical Immunology, 2013present and activated in the airway lumen and tissue 1 of patients with current asthma, that the cells are increased in number when asthma is uncontrolled or severe 2 and decreased in number when asthma is controlled, 3 and that treatment strategies that aim to control airway eosinophilia are significantly more effective and less expensive in improving
Parameswaran Nair
exaly +3 more sources
Phenotyping, Precision Medicine, and Asthma
Seminars in Respiratory and Critical Care Medicine, 2022AbstractThe traditional one-size-fits all approach based on asthma severity is archaic. Asthma is a heterogenous syndrome rather than a single disease entity. Studies evaluating observable characteristics called phenotypes have elucidated this heterogeneity.
Arjun, Mohan, Njira L, Lugogo
openaire +2 more sources
Introduction to Asthma and Phenotyping
2013Asthma is an inflammatory disorder characterized by airway obstruction, airway hyperresponsiveness, and airway inflammation, all of which are variable among patients and variable in time within any specific patient. Understanding the mechanism that underlies this observed variability, and using that understanding to advance the science of asthma and ...
Regina A, Pillai, William J, Calhoun
openaire +2 more sources
How to Diagnose and Phenotype Asthma
Clinics in Chest Medicine, 2012Asthma has been described as a chronic disease of the airways characterized by variable airflow obstruction, airway hyperresponsiveness, and airway inflammation. This review discusses the diagnosis and phenotyping of asthma, with a special emphasis on phenotyping based on the nature of cellular inflammation and radiological imaging and how this could ...
Nair, P +3 more
openaire +3 more sources
Current Opinion in Pulmonary Medicine, 2004
Asthma is a phenotypically heterogeneous disorder and, over the years, many different clinical subtypes of asthma have been described. A precise definition of asthma phenotypes is now becoming more and more important, not only for a better understanding of pathophysiologic mechanisms, but in particular to ascertain the specific genes associated with ...
openaire +2 more sources
Asthma is a phenotypically heterogeneous disorder and, over the years, many different clinical subtypes of asthma have been described. A precise definition of asthma phenotypes is now becoming more and more important, not only for a better understanding of pathophysiologic mechanisms, but in particular to ascertain the specific genes associated with ...
openaire +2 more sources
Asthma Phenotypes: Nonallergic (Intrinsic) Asthma
The Journal of Allergy and Clinical Immunology: In Practice, 2014The definition of nonallergic asthma includes that subset of subjects with asthma and with whom allergic sensitization cannot be demonstrated. These individuals should have negative skin prick test or in vitro specific-IgE test to a panel of seasonal and perennial allergens.
openaire +2 more sources
Phenotypes of asthma in mothers have an influence on asthma phenotypes in children
7.2 Paediatric Asthma and Allergy, 2016Background. Children born from mothers with bronchial asthma are the most vulnerable group for development of allergic diseases including asthma. Aim. We want to explore asthma phenotypes in children from mothers with various asthma phenotypes. Materials. We have examined 123 pregnant women with bronchial asthma and their newburns.
Liudmila Zhelenina +5 more
openaire +1 more source
Obesity and asthma disease phenotypes
Current Opinion in Allergy & Clinical Immunology, 2012The increasing prevalence of both asthma and obesity is associated with substantial morbidity and healthcare utilization. Herein, we review recent data suggesting that the obese asthmatic may represent a distinct clinical phenotype.Obesity is a major risk factor for asthma, and asthma in obese patients appears to be more difficult to control, with ...
Amanda R, Stream, E Rand, Sutherland
openaire +2 more sources
Age is associated with asthma phenotypes
Respirology, 2017ABSTRACTBackground and objectiveThe relationship between age and asthma phenotypes is important as population is ageing, asthma is becoming common in older ages and recently developed treatments for asthma are guided by phenotypes. The aim of this study is to evaluate whether age is associated with specific asthma phenotypes.MethodsThis is a cross ...
Ponte, Eduardo V. +7 more
openaire +2 more sources