Berberine chloride hydrate impairs Streptococcus mutans biofilm formation via inhibiting sortase A activity. [PDF]
NPJ Biofilms MicrobiomesZhou Y, Huang F, Lin H.
europepmc +1 more source
Investigation of the active ingredients and mechanism of Shuangling extract in dextran sulfate sodium salt induced ulcerative colitis mice based on network pharmacology and experimental verification. [PDF]
J Tradit Chin MedMengzhen C +5 more
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Bioavailability Enhancement of Astilbin in Rats through Zein–Caseinate Nanoparticles
Journal of Agricultural and Food Chemistry, 2019 Astilbin-encapsulated zein-caseinate nanoparticles were fabricated through the antisolvent method. The encapsulation and loading efficiency of astilbin in the nanoparticles were determined by high-performance liquid chromatography. The nanoparticles were characterized by particle size, ζ potential, redispersibility, scanning electron microscopy, X-ray ...
Qing-Feng Zhang
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Metabolism, Excretion, and Tissue Distribution of Astilbin–Zein Nanoparticles in Rats
Journal of Agricultural and Food Chemistry, 2019 The excretion, tissue distribution, and metabolic profile of astilbin in rat were studied by HPLC and UPLC-QTOF-MS. Astilbin underwent isomerization in the small intestine, and its four isomers were found in feces. Besides, taxifolin, the aglycone of astilbin, and its further metabolites by gut microbes through hydrogenation, dehydration, and ring ...
Qing-Feng Zhang
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Aqueous Stability of Astilbin: Effects of pH, Temperature, and Solvent
Journal of Agricultural and Food Chemistry, 2013The influence of temperature, pH value, and solvent on the degradation behavior of astilbin was studied by HPLC. Results showed that the degradation of astilbin was pH and temperature dependent, and the isomerization of astilbin to its three stereoisomers was found.
Qing-Feng Zhang
exaly +3 more sources
Astilbin decreases proliferation and improves differentiation in HaCaT keratinocytes
Biomedicine and Pharmacotherapy, 2017 Psoriasis is a common chronic dermatosis characterized by keratinocyte hyperproliferation accompanied by inflammatory reactions. Pathological changes upset the balance between keratinocyte proliferation, differentiation, and death in psoriatic lesions, suggesting that molecules with topical anti-inflammatory, anti-proliferation and anti-angiogenesis ...
Qingqing Xu +2 more
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Pest Management Science, 2002 Astilbin was isolated in high yield from Dimorphandra mollis, and its insecticidal and growth inhibiting activity by stomach ingestion were evaluated against Anticarsia gemmatalis and Spodoptera frugiperda.
Osmar Malaspina +2 more
exaly +2 more sources
Comparative study of the interaction mechanism of astilbin, isoastilbin, and neoastilbin with CYP3A4
Luminescence, 2023AbstractThe interactions of human CYP3A4 with three selected isomer flavonoids, such as astilbin, isoastilbin and neoastilbin, were clarified using spectral analysis, molecular docking, and molecular dynamics simulation. During binding with the three flavonoids, the intrinsic fluorescence of CYP3A4 was statically quenched in static mode with ...
Yanzhou Tao +7 more
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Astilbin from Engelhardtia chrysolepis enhances intestinal barrier functions in Caco-2 cell monolayers [PDF]
European Journal of Pharmacology, 2017 Astilbin, which is one of polyphenolic compounds isolated from the leaves of Engelhardtia chrysolepis HANCE (Chinese name, huang-qui), is available as the effective component in food and cosmetics because of its anti-oxidant and anti-inflammatory effects.
Masaru Yoshida, Shin Nishiumi
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The natural source, physicochemical properties, biological activities and metabolism of astilbin
Critical Reviews in Food Science and Nutrition, 2022Astilbin is a dihydroflavanol found in many plants and processed foods. Astilbin possesses multiple health-beneficial bioactivities and has received great attention. Hence, the natural source, physicochemical properties, biological activities and metabolism of astilbin are summarized in the present article. Engelhardia roxburghiana Wall.
Dan, Yang, Qing-Feng, Zhang
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