Results 11 to 20 of about 1,134 (185)
Astilbin Inhibits the Activity of Sortase A from Streptococcus mutans [PDF]
Molecules, 2019 Streptococcus mutans (S. mutans) is the primary etiological agent of dental caries. The S. mutans enzyme sortase A (SrtA) is responsible for anchoring bacterial cell wall surface proteins involved in host cell attachment and biofilm formation. Thus, SrtA
Junxian Wang +5 more
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Brazilian Journal of Pharmaceutical Sciences, 2022 Lysiphyllum strychnifolium (Craib) A. Schmitz. (in Thai name, Ya nang daeng) has been traditionally used to treat fever, alcohol intoxication, cancer, allergies, and blood toxins.
Yupaporn Sampaopan +1 more
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Production of Taxifolin from Astilbin by Fungal Biotransformation
Catalysts, 2022 Taxifolin is known to have multiple biological functions. It has been widely used as a multifunctional food additive, and consequently, the global demand for taxifolin is increasing. The main method for taxifolin production is an extraction from larch wood, but the global resources of larch are limited.
Jianfeng Mei +5 more
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Molecules, 2020 Astilbin and neoastilbin are two flavonoid stereoisomers. In the present study, their solubility, stability, and bioavailability were compared in a rat.
Dan Zheng +3 more
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Astilbin Inhibits High Glucose-Induced Inflammation and Extracellular Matrix Accumulation by Suppressing the TLR4/MyD88/NF-κB Pathway in Rat Glomerular Mesangial Cells [PDF]
Frontiers in Pharmacology, 2018 Diabetic nephropathy (DN) is characterized by inflammatory responses and extracellular matrix (ECM) accumulation. Astilbin is an active natural compound and possesses anti-inflammatory activity. The aim of this study was to evaluate the anti-inflammatory
Fang Chen +3 more
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BMC Complementary Medicine and Therapies, 2023 Introduction Bioactive compounds from traditional medicines are good alternatives to standard diabetes therapies and may lead to new therapeutic discoveries. The stems of Bauhinia strychnifolia Craib.
Komgrit Eawsakul +3 more
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Decrease of Functional Activated T and B Cells and Treatment of Glomerulonephitis in Lupus-Prone Mice Using a Natural Flavonoid Astilbin. [PDF]
PLoS ONE, 2015 Treatment of systemic lupus erythematosus (SLE), a chronic inflammatory disease, involves the long-term use of immunosuppressive agents with significant side effects.
Lele Guo +10 more
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Astilbin Inhibits RANKL-Induced Osteoclasts by Suppressing PI3K/Akt Signaling Pathway
Journal of ChemistryThis study evaluated the in vitro and in vivo antiresorptive effects of astilbin, isolated from Smilax glabra Roxb roots, on RANKL-induced osteoclastogenesis using RAW 264.7 cell culture and a transgenic medaka (Oryzias latipes) fish model of ...
Huyen T. T. Nguyen +7 more
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Inhibition of peroxidase activity and scavenging of reactive oxygen species by astilbin isolated from Dimorphandra mollis (Fabaceae, Caesalpinioideae) [PDF]
Biological Research, 2010 Astilbin (5,7,3’,4’-tetrahydroxy-2,3-dihydroflavonol-3-ß-o-rhamnoside), a flavonoid with a large range of biological activities, was isolated from Dimorphandra mollis, a shrub common to the Brazilian Cerrado.
FERNANDO PETACCI +3 more
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Molecules, 2015 Astilbin, a dihydroflavonol derivative found in many food and medicine plants, exhibited multiple pharmacological functions. In the present study, the ethanol extraction of astilbin from the rhizome of smilax glabra Roxb was optimized by response surface
Chuan-Li Lu +6 more
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