Results 201 to 210 of about 194,703 (370)
FABP4 as a Mediator of Lipid Metabolism and Pregnant Uterine Dysfunction in Obesity
Advanced Science, EarlyView.Obesity during late pregnancy contributes to uterine smooth muscle dysfunction, but the underlying mechanisms are unclear. This study identifies fatty acid binding protein 4 (FABP4) as a key player in the process, mediating excessive fatty acid uptake, lipid accumulation, and mitochondrial dysfunction in myometrial cells. FABP4 could be a novel uterine
Xuan Li +11 more
wiley +1 more source
Brain and Behavior, Volume 12, Issue 12, December 2022., 2022 Abstract Objective This study sought to evaluate the feasibility of multifunctional gastrodin (GAS)‐containing nano‐drug carrier system against cerebral ischemia–reperfusion injury (CIRI). Methods The drug‐loaded nanocomposite (Au‐G5.NHAc‐PS/GAS) with certain encapsulation efficiency (EE) was prepared by physical adsorption method using different ...
Wenqiang Huang +8 more
wiley +1 more source
Neurobiology of Disease, 2010 Astrocyte dysfunction may contribute to epileptogenesis and other neurological deficits in Tuberous Sclerosis Complex (TSC). In particular, decreased expression and function of astrocyte glutamate transporters have been implicated in causing elevated ...
Ling-Hui Zeng +4 more
doaj
Firing rate model for brain rhythms controlled by astrocytes [PDF]
arXivWe propose a new mean-field model of brain rhythms governed by astrocytes. This theoretical framework describes how astrocytes can regulate neuronal activity and contribute to the generation of brain rhythms. The model describes at the population level the interactions between two large groups of excitatory and inhibitory neurons.
arxiv
Heparan sulfate proteoglycan and laminin immunoreactivity on cultured astrocytes: relationship to differentiation and neurite growth [PDF]
, 1988 MD Ard, RP Bunge
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HDAC6 and USP9X Control Glutamine Metabolism by Stabilizing GS to Promote Glioblastoma Tumorigenesis
Advanced Science, EarlyView.Glioblastoma (GBM) growth relies on glutamine synthetase (GS), which is stabilized by histone deacetylase 6 (HDAC6) and deubiquitinated by ubiquitin‐specific peptidase 9, X‐linked (USP9X). HDAC6 promotes GS deacetylation, while USP9X removes its K48‐linked polyubiquitination, enhancing GS stability.
Go Woon Kim +9 more
wiley +1 more source
HISTOPATHOLOGICAL STUDY ON ASTROCYTE IN VARIOUS LIVER DISEASES PART I
, 1979 Hideki Kida, Shigemi Anraku
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Astrocyte membrane structure: changes after circulatory arrest. [PDF]
, 1981 Dennis M.D. Landis, Thomas S. Reese
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Advanced Science, EarlyView.A novel “prof” cocktail therapy is designed. It screens antigens, selects personalized antigen panels, engineers optimized CAR‐Vδ1 T cells, and tests in patient‐derived GBM organoids, offering hope for effective CAR‐T drugs against heterogeneous solid tumors. Abstract Various challenges, including tumor heterogeneity and inadequate T cell infiltration,
Guidong Zhu +12 more
wiley +1 more source