Results 221 to 230 of about 303,608 (351)

Functional characteristics, intercellular interactions and pathophysiological associations of astrocytes in Parkinson's disease. [PDF]

PeerJ
Li Z, Cao M, Yin Z, Li X, Wang Q, Dong P, Zhou C.   +6 more
europepmc   +1 more source

Igfbp2 Downregulation in PVT‐CeA Glutamatergic Circuits Drives Neonatal Anesthesia‐Induced Fear Memory Deficits

Advanced Science, EarlyView.
Repeated neonatal sevoflurane exposure impairs adolescent fear memory through Igfbp2 downregulation in paraventricular thalamus‐central amygdala glutamatergic projections. Restoring Igfbp2 or activating this circuit rescues memory deficits, neuronal excitability, and spine density, identifying a precise molecular target for preventing anesthesia ...
Weiming Zhao, Ke Peng, Baojian Zhao, Xiaowen Meng, Gang Wang, Hanbing Xu, Li Deng, Xisheng Shan, Yichan Wang, Qiya Xu, Yanan Gao, Ruixia Weng, Hong Liu, Jin Tao, Huayue Liu, Shaoyong Song, Fuhai Ji   +16 more
wiley   +1 more source

Immunocytochemical detection of astrocyte GABAA receptors in cat visual cortex. [PDF]

, 1993
A. M. Rosier, Lut Arckens, Guy A. Orban, Frans Vandesande   +3 more
openalex   +1 more source

The mGluR5 agonist CHPG enhances human oligodendrocyte differentiation. [PDF]

Acta Neuropathol Commun
Huang Y, Geywitz C, Bandaru A, Glass IA, Birth Defects Research Laboratory, Schirmer L, Nobuta H, Dreyfus CF.   +7 more
europepmc   +1 more source

SURF: A Self‐Supervised Deep Learning Method for Reference‐Free Deconvolution in Spatial Transcriptomics

Advanced Science, EarlyView.
SURF is a robust reference‐free deconvolution tool that integrates high‐dimensional spatial transcriptomics gene expression analysis with self‐supervised deep learning, enabling effective modeling of non‐linear gene interactions and spot relationships.
Shuyu Liang, Zixia Zhou, Peng Huang, Junhu Fu, Jing Jiao, Yunxia Huang, Shichong Zhou, Guanlin Wang, Yuanyuan Wang, Yi Guo   +9 more
wiley   +1 more source

Sigma-1 receptor counteracts non-cell-autonomous poly-PR-induced astrocytic oxidative stress in C9orf72 ALS. [PDF]

Redox Biol
Wu HC, Huang TW, Weng EF, Lin CY, Su TP, Wu HE, Wang SM.   +6 more
europepmc   +1 more source

NADPH Oxidase Inhibition Promotes Brain Resilience by Attenuating Tauopathy and Neuroinflammation in Alzheimer's Disease

Advanced Science, EarlyView.
CRB‐2131, as a novel Nox inhibitor, suppresses brain oxidation, tauopathy, and neuro‐inflammation, thereby preventing death of mature neurons and promoting regeneration of immature neurons. Ultimately, this fosters a resilient brain and protects cognition.
Jihyeon Lee, Seunghwan Sim, Yinglan Jin, Hyejun Park, Eun Young Byeon, Su Jin Kim, Sujin Yun, Hye Eun Lee, Da Un Jeong, Jung Min Suh, In Hye Lee, Ho‐Young Lee, Yongseok Choi, Yun Soo Bae   +13 more
wiley   +1 more source

Characterization of a novel binding site for the human immunodeficiency virus type 1 envelope protein gp120 on human fetal astrocytes [PDF]

, 1994
Meihui Ma, Jonathan D. Geiger, Avindra Nath   +2 more
openalex   +1 more source

NRC31 limits the imprinting of astrocyte epigenetic inflammatory memory early in life. [PDF]

Nat Commun
Lee HG, Quintana FJ.
europepmc   +1 more source

Elevated Apolipoprotein E Expression in Hippocampal Microglia Drives Temporal Lobe Epilepsy Progression

Advanced Science, EarlyView.
In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi, Zesheng Li, Xin Sun, Yanfeng Yang, Yumin Luo, Ziang Song, Hengxin Dong, Lei Jin, Jing Xie, Yongzhi Shan, Guoguang Zhao   +10 more
wiley   +1 more source