Spinal astrocyte-derived interleukin-17A promotes pain hypersensitivity in bone cancer mice
Spinal microglia and astrocytes are both involved in neuropathic and inflammatory pain, which may display sexual dimorphism. Here, we demonstrate that the sustained activation of spinal astrocytes and astrocyte-derived interleukin (IL)-17A promotes the ...
Huizhu Liu+6 more
doaj
Rethinking Sensory Information Processing: The Essential Role of Astrocytes. [PDF]
Rosa JM, Aguilar J.
europepmc +1 more source
A wireless‐charging sustained oxygen release from conductive microgels (SOCO) served as an antenna and an on‐demand O2 release for nerve regeneration is developed. Introducing “electromagnetic messenger”, using external alternating magnetic field (AMF) to enhance catalytic oxygen release and electrical stimulation to promote the reconstruction of blood
Hoi Man Iao+15 more
wiley +1 more source
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force initiated the TASK3 working group to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Eleonora Aronica+6 more
wiley +1 more source
Research progress on the role of exercise-regulated reactive astrocytes in the prevention and treatment of Parkinson's disease. [PDF]
Yang Q, Zhuang C.
europepmc +1 more source
Effects of transforming growth factor-beta on murine astrocyte glutamine synthetase activity. Implications in neuronal injury. [PDF]
C C Chao+6 more
openalex +1 more source
β‐Mangostin alleviates intervertebral disc degeneration through dual modulation of macrophage polarization and the TET2‐Prkcg axis in nucleus pulposus cells. Abstract Intervertebral disc degeneration (IDD) induced lower back pain is a main cause of disability, resulting in a substantial workforce loss worldwide and placing a substantial burden on the ...
Xiangzhen Kong+15 more
wiley +1 more source
Usp18 Mediates D-Dopachrome Tautomerase-Induced Astrocytic Inflammation After Spinal Cord Injury. [PDF]
Zhang X+11 more
europepmc +1 more source
An Amygdala‐hippocampus Circuit for Endocannabinoid Modulation of Anxiety Avoidance
This study employs three synapse‐specific endocannabinoids (eCB) probes to monitor dynamic eCB release, activate CB1Rs and knockdown 2‐AG biosynthesis enzymes in glutamatergic anterior basolateral amygdala ‐ ventral hippocampus (aBLA–vHPC) circuit. At aBLA–vHPC circuits, activation of CB1Rs reduce anxiety avoidance, and knockdown of eCB biosynthesis ...
Bao Xue+9 more
wiley +1 more source
Potential for flexible lactate shuttling between astrocytes and neurons to mitigate against diving-induced hypoxia. [PDF]
Ciccone C+7 more
europepmc +1 more source