Results 281 to 290 of about 461,223 (386)

Astrocyte-intrinsic signaling of chitinase-like protein CHI3L1 drives inflammation and amplifies demyelination in neuromyelitis optica. [PDF]

J Clin Invest
Xu H, Jiang W, Xu L, Li H, Yang X, Zhu F, He P, Song Y, Li Y, Huang YA, Qiu W, Tang C.   +11 more
europepmc   +1 more source

Changes in the nuclei of astrocytes following portacaval shunting and portacaval transposition in the rat.

, 1978
Daniel Doyle, C. J. Ryan, I S Benjamin, Leslie H. Blumgart   +3 more
openalex   +1 more source

Targeting G3BP1 Condensate Topology Promotes Stress Granule Assembly via m6A‐IGF2BP1 for Ischemic Stroke Rescue

Advanced Science, EarlyView.
Our research reveals that small‐molecule icariin (ICA) directly binds Ras‐GTPase‐activating protein SH3 domain‐binding protein 1 (G3BP1), inducing conformational change and oligomerization. This interaction confers neuroprotection by recruiting insulin‐like growth factor 2 mRNA‐binding protein 1 (IGF2BP1) and modulating N6‐methyladenosine (m6A ...
Ling Li, Yong‐Dong Guo, Xiao‐Wen Zhang, Zhi‐Yong Du, Yu‐Qi Wang, Zhuo Yang, Qian‐Wei Luo, Fang‐Fang Zhuo, Tian‐Tian Wei, Zheng‐Ping Liu, Bo Han, Wei Yu, Pei‐Pei Zhang, Wei Zhou, Zhi‐Yuan Lu, Peng‐Fei Tu, Chun‐Hong Zheng, Ke‐Wu Zeng   +17 more
wiley   +1 more source

Chronic Stress and Astrocyte Dysfunction in Depression: Molecular Mechanisms and Gene Expression Changes. [PDF]

Antioxidants (Basel)
Bochenska N, Tomczak J, Lisek M.
europepmc   +1 more source

Update: Data on the responses of neurons and astrocytes to oxidative injury in the presence of insulin-like growth factor I

, 2014
Laura Genı́s, David Dávila, Silvia Fernández, Andrea Pozo-Rodrigálvarez, Ricardo Martı́nez-Murillo, Ignacio Torres‐Alemán   +5 more
openalex   +1 more source

Label‐Free Molecular Characterization of Protein Aggregates in Differentiated Astrocytes

Advanced Science, EarlyView.
Mid‐infrared photothermal microscopy enables label‐free structural, molecular, and functional imaging of protein aggregates in astrocyte cells. The processes of astrocytes differentiated on a nanomaterial interface are characterized by α‐helical signatures combined with enhanced interfacial thermal resistance properties, while the cell soma of non ...
Panagis D. Samolis, Chiara Lazzarini, Rahmetullah Durgun, Barbara Barile, Giorgia Conte, Tamara Posati, Marco Caprini, Grazia Paola Nicchia, Valentina Benfenati, Michelle Y. Sander   +9 more
wiley   +1 more source

Role of Reactive Astrocytes and Microglia: Wnt/β-Catenin Signaling in Neuroprotection and Repair in Parkinson's Disease. [PDF]

Int J Mol Sci
Grasso M, Mascali C, L'Episcopo F.
europepmc   +1 more source

Author response: PTBP1 Depletion in Mature Astrocytes Reveals Distinct Splicing Alterations Without Neuronal Features

Min Zhang, Naoto Kubota, David Nikom, Ayden Arient, Sika Zheng   +4 more
openalex   +1 more source

A Blood‐Brain Barrier‐Penetrant Ag(III) Corrole Compound Rescues Alzheimer's Disease Pathology by Targeting Aβ42‐Induced Oxidative Stress

Advanced Science, EarlyView.
The newly designed metallo‐corrole (Mor‐Cor)Ag(III) with a morpholino group exhibited promising therapeutic potential for Alzheimer's disease. It significantly reduces reactive oxygen species (ROS), decreases GFAP expression, increases neurite length, and decreases cell death compared to other similar metallo‐corroles. Abstract Alzheimer's disease (AD)
Arup Tarai, Tuhina Mitra, Tanmoy Pain, Jyotiprakash Mallick, Rwiddhi Chakraborty, Kallam Tejaswi, Swagata Ghatak, Sanjib Kar   +7 more
wiley   +1 more source

Astrocytic and microglial cell functions in neuroinflammatory diseases and their animal models. [PDF]

Front Cell Neurosci
Hashimoto K, Gotoh M, Ikeshima-Kataoka H.   +2 more
europepmc   +1 more source