Results 281 to 290 of about 303,608 (351)

NR3C1-mediated epigenetic regulation suppresses astrocytic immune responses in mice. [PDF]

open access: yesNat Commun
Park S   +9 more
europepmc   +1 more source

Computational Fluid Dynamic Model Prediction of Enhanced Glymphatic Clearance in Response to Focused Ultrasound‐Mediated Blood‐Brain Barrier Opening

open access: yesAdvanced Science, EarlyView.
Focused ultrasound‐mediated blood‐brain barrier opening (FUS BBBO) for enhanced drug delivery also augments glymphatic clearance. A computational model of an arteriole‐venule pair in the brain offers insight into the underlying biotransport mechanisms responsible for this mass clearance effect.
Ryan A. Gladwell   +5 more
wiley   +1 more source

Partial Reprogramming in Senescent Schwann Cells Enhances Peripheral Nerve Regeneration via Restoration of Stress Granule Homeostasis

open access: yesAdvanced Science, EarlyView.
In this study, it is discovered that pathological accumulation of Runx2+ Schwann cell clusters​ during axonal regeneration is a key factor impairing nerve repair in aging. This pathology is associated with ​dysregulation of stress granule homeostasis.
Peilin Wang   +10 more
wiley   +1 more source

Assessing the Nature of Human Brain‐Derived Extracellular Vesicles on Synaptic Activity Via the Development of an Air‐liquid Microfluidic Platform

open access: yesAdvanced Science, EarlyView.
This seminal study highlights the interwoven and tightly regulated functions of brain‐derived extracellular vesicles. Using microfluidics, proteomics, and AI‐based electric signal analyses of cortical brain explants, this work provides a useful resource dataset revealing the composition of human brain‐derived extracellular vesicles obtained from ...
Corentin Bernou   +14 more
wiley   +1 more source

Distinct reduction in relative microglial glucose uptake compared to astrocytes and neurons upon isolation from the brain environment. [PDF]

open access: yesFront Cell Neurosci
Kunte ST   +13 more
europepmc   +1 more source

Ultrafine Molybdenum Wire Braided Neurointerventional Implants: Bridging Biodegradability and Neurovascular Safety for Stroke Treatment

open access: yesAdvanced Science, EarlyView.
Molybdenum (Mo), with its unique strength, uniform corrosion, and radiopacity, enables innovative biodegradable implants for transformative stroke therapy. Abstract Neurovascular implants for stroke intervention face a critical dilemma: permanent devices (e.g., nitinol stents, platinum coils) often trigger chronic inflammation and recurrence, whereas ...
Yunong Shen   +11 more
wiley   +1 more source

Increased Fos immunoreactivity in astrocytes in the raphe pallidus under hypoxia, not hypercapnia. [PDF]

open access: yesHistochem Cell Biol
Kato K   +4 more
europepmc   +1 more source

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