Results 281 to 290 of about 123,114 (319)
A head start: The relationship of placental factors to craniofacial and brain development
Developmental Dynamics, EarlyView.Abstract In recent years, the importance of placental function for fetal neurodevelopment has become increasingly studied. This field, known as neuroplacentology, has greatly expanded possible etiologies of neurodevelopmental disorders by exploring the influence of placental function on brain development.
Annemarie Jenna Carver +2 more
wiley +1 more source
Dynamic expression of lamin B1 during adult neurogenesis in the vertebrate brain
Developmental Dynamics, EarlyView.Abstract Background In mammals, specific brain regions such as the dentate gyrus (DG) of the hippocampus and the subventricular zone (SVZ) of the lateral ventricles harbor adult neural stem/progenitor cells (ANSPCs) that give rise to new neurons and contribute to structural and functional brain plasticity.
Diana Zhilina +12 more
wiley +1 more source
International Journal of Eating Disorders, EarlyView.ABSTRACT Objective Anorexia nervosa (AN) is associated with hyperactivity, amenorrhea, and brain atrophy. Weight rehabilitation reversed these symptoms, although the underlying pathophysiological mechanisms are mostly unknown. Serum neurofilament light chain (NfL) levels are widely used as a biomarker of neurodegeneration. Based on neuroimaging studies
Annelie Zimmermann +16 more
wiley +1 more source
Epileptic Disorders, EarlyView.Abstract Objective Temporal lobe epilepsy (TLE) is the most prevalent form of epilepsy. Prior research has indicated the involvement of the nucleus accumbens shell (NAcSh) in the process of epileptogenesis, thereby implying its potential as a therapeutic target for TLE.
Shuaishuai Xue +10 more
wiley +1 more source
Exploring biomarkers of neurodegeneration in epilepsy: Critical insights
Epileptic Disorders, EarlyView.Abstract The advent of biofluid biomarkers for neurodegenerative disorders has precipitated a surge in recent evidence regarding their role in epilepsy. In this literature review, we examine the diagnostic, prognostic, and therapeutic potential of several biomarkers, including amyloid‐beta (Aβ) protein, total (t‐tau), phosphorylated tau (p‐tau) protein,
Rida Farhan +7 more
wiley +1 more source
New insights into epileptic spasm generation and treatment from the TTX animal model
Epilepsia Open, EarlyView.Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann +2 more
wiley +1 more source
Tau‐targeting nanoparticles for treatment of Alzheimer's disease
Exploration, EarlyView.Through review of comprehensive literature and research studies, it is found that tau‐targeting nanoparticles may posit beneficial applications to AD therapy. By targeting a key molecular mechanism known to propagate AD pathogenesis, tau‐targeting nanoparticles have the potential to facilitate tau tangle clearance, promote synaptic integrity, and ...
Shreya Pawar +3 more
wiley +1 more source
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Current Biology, 2021
Philip Hasel and Shane Liddelow introduce astrocytes - glial cells that help to maintain the homeostasis of the central nervous system during development, normal physiology, and aging.
Philip, Hasel, Shane A, Liddelow
openaire +2 more sources
Philip Hasel and Shane Liddelow introduce astrocytes - glial cells that help to maintain the homeostasis of the central nervous system during development, normal physiology, and aging.
Philip, Hasel, Shane A, Liddelow
openaire +2 more sources