Results 121 to 130 of about 87,340 (291)

Stroke‐Like Migraine Attacks After Radiation Therapy (SMART) Syndrome: A Case Report and Review of a Rare Delayed Complication of Cranial Irradiation

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT SMART syndrome is a rare, delayed complication of cranial irradiation that can mimic stroke, tumor recurrence, or autoimmune encephalitis. Early recognition based on clinical‐radiologic features is critical to avoid misdiagnosis and unnecessary interventions since conservative management often leads to complete recovery.
Shiv Jha, Yugant Khand, Surabhi Ranjan, Monika Pandit, Eric Mariuma   +4 more
wiley   +1 more source

Metabolic reprogramming of efferocytosis in the tumour microenvironment: From apoptotic‐cell clearance to therapeutic targeting

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
This review systematically deconstructs the pathological efferocytic—metabolic axis in tumours, framing it as a three‐stage, self‐reinforcing cycle: from metabolite‐driven macrophage recruitment, through hijacked surface recognition, to post‐phagocytic metabolic reprogramming that locks in immunosuppression.
Qianlu Yang, Jie Yan, Qianxi Yang
wiley   +1 more source

DNA methylation-based classification of central nervous system tumours. [PDF]

, 2018
Accurate pathological diagnosis is crucial for optimal management of patients with cancer. For the approximately 100 known tumour types of the central nervous system, standardization of the diagnostic process has been shown to be particularly challenging-
Aronica, Eleonora, Becker, Albert, Benner, Axel, Beschorner, Rudi, Bewerunge-Hudler, Melanie, Bjerkvig, Rolf, Braczynski, Anne K, Brehmer, Stefanie, Brück, Wolfgang, Calaminus, Gabriele, Capper, David, Chavez, Lukas, Coras, Roland, Cryan, Jane, Deckert, Martina, Dohmen, Hildegard, Driever, Pablo Hernáiz, Engel, Nils W, Farrell, Michael, Fischer, Roger, Fleischhack, Gudrun, Frank, Stephan, Frühwald, Michael C, Garvalov, Boyan K, Geisenberger, Christoph, Giangaspero, Felice, Gnekow, Astrid, Gottardo, Nicholas G, Haberler, Christine, Hans, Volkmar, Hansford, Jordan R, Harter, Patrick N, Hench, Jürgen, Heppner, Frank, Hewer, Ekkehard, Hofer, Silvia, Hovestadt, Volker, Huang, Kristin, Hänggi, Daniel, Hölsken, Annett, Jones, Chris, Jones, David TW, Jouvet, Anne, Kannan, Kasthuri, Keohane, Catherine, Ketter, Ralf, Khatib, Ziad, Koch, Arend, Koelsche, Christian, Kohlhof, Patricia, Kramm, Christof M, Kratz, Annekathrin, Kristensen, Bjarne W, Kulozik, Andreas, Lechner, Matt, Lindenberg, Kerstin, Lohmann, Dietmar, Lopes, Beatriz, Mawrin, Christian, Milde, Till, Monoranu, Camelia-Maria, Mueller, Wolf, Mühleisen, Helmut, Müller, Hermann L, Olar, Adriana, Pages, Melanie, Pajtler, Kristian W, Perry, Arie, Plate, Karl H, Pohl, Ute, Preusser, Matthias, Prinz, Marco, Reuss, David E, Rodriguez, Fausto J, Rozsnoki, Stephanie, Rushing, Elisabeth, Rutkowski, Stefan, Sahm, Felix, Scheurlen, Wolfram, Schick, Matthias, Schittenhelm, Jens, Schrimpf, Daniel, Schweizer, Leonille, Seiz-Rosenhagen, Marcel, Selt, Florian, Serrano, Jonathan, Sill, Martin, Staszewski, Ori, Stichel, Damian, Sturm, Dominik, Temming, Petra, Tippelt, Stephan, Tsirigos, Aristotelis, Varlet, Pascale, von Hoff, Katja, Wani, Khalida, Wefers, Annika K, Witt, Hendrik, Witt, Olaf, Zapatka, Marc   +99 more
core   +1 more source

Integrative Single‐Cell Analysis Reveals Targetable Vacuole Membrane Protein 1‐Mediated Mechanism of Tumor Angiogenesis in Glioblastoma

MedComm, Volume 7, Issue 2, February 2026.
VMP1 promotes angiogenesis in glioblastoma (GBM) through VEGFA‐VEGFR2 signaling and activation of endothelial cells. The FDA‐approved anti‐VEGFA antibody, bevacizumab (BEV), can counteract VMP1's tumor‐promoting effect in GBM. Targeting VMP1 or its associated pathways could be a new therapeutic strategy, either alone or in combination with BEV.
Lei Jin, Bo Chen, Junbo Liao, Wenlong Guo, Zhiyuan Zhu, Salida Ali, Gilberto Ka‐Kit Leung, Peng Wang, Karrie M. Kiang   +8 more
wiley   +1 more source

T1ρ$$ {}_{1\rho } $$ as a Biomarker for IDH1 Mutation Status in a Glioma Mouse Model

NMR in Biomedicine, Volume 39, Issue 2, February 2026.
Mice bearing IDH1‐mutant and ‐wild‐type glioma underwent quantitative T1ρ$$ {T}_{1\rho } $$ imaging over the course of tumour development. It was found that while IDH1‐wild‐type tumours present similar T1ρ$$ {T}_{1\rho } $$ values as the brain, IDH1‐mutant tumours exhibit significantly higher T1ρ$$ {T}_{1\rho } $$ values compared with the brain. T1ρ$$ {
Hannah J. S. Ehler, Saki Sultana, Christa Davis, Kimberly Brewer, James Rioux   +4 more
wiley   +1 more source

Melanoma of the Choroid and Ciliary Body in Children: Remission of Metastatic Melanoma of the Choroid After Treatment With Chemotherapy and Immune Checkpoint Inhibition

Pediatric Blood &Cancer, Volume 73, Issue 2, February 2026.
ABSTRACT Background Uveal melanoma is the most common malignant primary intraocular tumor in adults, associated with high mortality. Pediatric uveal melanoma generally has a more favorable course. However, when metastasis occurs, therapeutic options are limited.
Pia Tüller, Tobias Kiefer, Leyla Jabbarli, Kyriaki Papaioannou, Kathrin Schramm, Nicole Barwinski, Stefan Schönberger, Ines B. Brecht, Dominik T. Schneider, Elisabeth Livingstone, Lisa Zimmer, Karen Fischhuber, Andreas Junker, Saskia Ting, Cordula Kiewert, Sophia Göricke, Nikolaos Bechrakis, Eva Biewald, Petra Ketteler   +18 more
wiley   +1 more source

Intermediate pilomyxoid astrocytoma and diencephalic syndrome: imaging findings

Einstein (São Paulo), 2012
Pilomyxoid astrocytoma, an entity described as a histological variant of pilocytic astrocytoma, is a rare primary tumor of the central nervous system.
Olavo Kyosen Nakamura, Marco da Cunha Pinho, Vicente Odone Filho, Sergio Rosemberg   +3 more
doaj  

GPNMB immunohistochemistry is a useful ancillary tool for the diagnosis of pulmonary lymphangioleiomyomatosis

Histopathology, Volume 88, Issue 3, Page 698-709, February 2026.
We evaluated the diagnostic utility of GPNMB immunohistochemistry in LAM. GPNMB showed strong expression in LAM cells, while the differential diagnostic mimics showed no or only low expression. Based on its 100% sensitivity and specificity in our cohort, GPNMB is a highly reliable immunohistochemical marker for the diagnosis of LAM.
Fatime Szalai, Judit Pápay, Katalin Dezső, Levente Kuthi, Anna Sebestyén, András Khoór, Ildikó Krencz   +6 more
wiley   +1 more source

Therapeutic targeting of chromatin alterations in leukemia and solid tumors

International Journal of Cancer, Volume 158, Issue 2, Page 382-408, 15 January 2026.
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner, Tobias Berg, Daniel Sasca, Sophie‐Luise Mersiowsky, Jayant Y. Gadrey, Johanna Thomas, Michael W. M. Kühn, Michael Lübbert   +7 more
wiley   +1 more source

Advances in Molecular Pathology, Diagnosis and Treatment of Spinal Cord Astrocytomas

Technology in Cancer Research & Treatment
Spinal cord astrocytoma (SCA) is a rare subtype of astrocytoma, posing challenges in diagnosis and treatment. Low-grade SCA can achieve long-term survival solely through surgery, while high-grade has a disappointing prognosis even with comprehensive ...
Zijun Zhao MD, Zihan Song MD, Zairan Wang MD, Fan Zhang MS, Ze Ding MS, Tao Fan MD   +5 more
doaj   +1 more source