Results 121 to 130 of about 109,064 (360)
The genetic landscape of anaplastic astrocytoma
OncoTarget, 2013 Anaplastic astrocytoma WHO grade III (A3) is a lethal brain tumor that often occurs in middle aged patients. Clinically, it is challenging to distinguish A3 from glioblastoma multiforme (GBM) WHO grade IV.
Patrick J. Killela +11 more
semanticscholar +1 more source
Hypoxic Cell Waves around Necrotic Cores in Glioblastoma: A Biomathematical Model and its Therapeutic Implications [PDF]
arXiv, 2012 Glioblastoma is a rapidly evolving high-grade astrocytoma that is distinguished pathologically from lower grade gliomas by the presence of necrosis and microvascular hiperplasia. Necrotic areas are typically surrounded by hypercellular regions known as "pseudopalisades" originated by local tumor vessel occlusions that induce collective cellular ...
arxiv
Journal of Magnetic Resonance Imaging, EarlyView.ABSTRACT Background Imaging‐based molecular characterization is important for identifying treatment targets in adult‐type diffuse gliomas. Purpose To assess isocitrate dehydrogenase (IDH) mutation and epidermal growth factor receptor (EGFR) amplification status in primary and recurrent gliomas using diffusion and perfusion MRI, addressing spatial and ...
Yun Hwa Roh +9 more
wiley +1 more source
Sulforhodamine 101 selectively labels human astrocytoma cells in an animal model of glioblastoma [PDF]
, 2014 Sulforhodamine 101 (SR101) is a useful tool for immediate staining of astrocytes. We hypothesized that if the selectivity of SR101was maintained in astrocytoma cells, it could prove useful for glioma research.
Anderson, Trent +9 more
core +1 more source
BMC Neurology, 2010 Background Human serum paraoxonase 1 (PON1) plays a major role in the metabolism of several organophosphorus compounds. The enzyme is encoded by the polymorphic gene PON1, located on chromosome 7q21.3. Aiming to identify genetic variations related to the
Martínez Carmen +5 more
doaj +1 more source
Intraventricular dissemination of the pilocytic astrocytomas in an adult
Romanian Neurosurgery, 2020 Pilocytic astrocytoma (PA) is a subset of gliomas characterized by a benign course with an excellent prognosis and rarely metastasizing or spreading along the neuraxis. We report a case of a 56-year female with intraventricular dissemination of pilocytic
Vijay P. Joshi +4 more
doaj +1 more source
Journal of Magnetic Resonance Imaging, EarlyView.ABSTRACT Background Glutamate and glutamine are critical metabolites in gliomas, each serving distinct roles in tumor biology. Separate quantification of these metabolites using in vivo MR spectroscopy (MRS) at clinical field strengths (≤ 3T) is hindered by their molecular similarity, resulting in overlapping, hence indistinguishable, spectral peaks ...
Seyma Alcicek +10 more
wiley +1 more source
Modeling brain dynamics in brain tumor patients using the virtual brain [PDF]
, 2018 Presurgical planning for brain tumor resection aims at delineating eloquent tissue in the vicinity of the lesion to spare during surgery. To this end, noninvasive neuroimaging techniques such as functional MRI and diffusion-weighted imaging fiber ...
Achten, Eric +6 more
core +1 more source
Pathological and molecular advances in pediatric low-grade astrocytoma.
Annual Review of Pathology, 2013 Pediatric low-grade astrocytomas are the most common brain tumors in children. They can have similar microscopic and clinical features, making accurate diagnosis difficult.
F. Rodriguez +3 more
semanticscholar +1 more source
Journal of Magnetic Resonance Imaging, EarlyView.ABSTRACT Background Tumor characterization and treatment efficacy are associated with tissue hypoxia. MR‐derived oxygen extraction fraction (OEF) may offer valuable tumor insights but depends on multiple measurement parameters, often requiring multiple sequence acquisitions.
Fabian Küppers +10 more
wiley +1 more source